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smartarray microarray chips capitalbio beijing china  (CapitalBio Corporation)

 
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    CapitalBio Corporation smartarray microarray chips capitalbio beijing china
    <t>Microarray</t> analysis uncovered an altered and specific transcriptional profile underlying the cell shape change and the suppression of the metastatic potential by Runx3. ( A ) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations assigned different repertoires of differentially expressed genes (DEGs) that were regulated by Runx3 in B16-F10 cells and, in the case of B16-F0 cells vs. B16-F10 cells, to the terms relevant to the actin cytoskeleton and adhesion. Each GO/KEGG annotation term is inscribed as a caption. The number of DEGs within a repertoire is described at x axis. The columns for the downregulated and the upregulated DEGs are shown in different colors as explained at the top of the figure., Down/Up by Runx3 indicates the appearance of DEGs in the case of B16-F10/Runx3 cells vs. mock control B16-F10 cells. Down/Up in B16-F0 indicates the appearance of DEGs in the case of B16-F0 cells vs. B16-F10 cells. Down/Up in common indicates the appearance of same DEGs in both cases. ( B ) Runx3 upregulated the expression of extracellular matrix (ECM) genes. The summary table indicates the gene names and their corresponding fold changes. ( C ) Runx3 regulated the expression of a list of DEGs that were inversely associated with an increase in the metastatic potential of B16-F10 cells compared to B16-F0 cells. The heatmap shows the gene names and their fold changes in the cases of B16-F10/Runx3 cells vs. mock control B16-F10 cells and B16-F0 cells vs. B16-F10 cells, respectively.
    Smartarray Microarray Chips Capitalbio Beijing China, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/smartarray+microarrayer/smartarray+microarray+chips+capitalbio+beijing+china/pmc07926509-61-0-3
    Average 90 stars, based on 1 article reviews
    smartarray microarray chips capitalbio beijing china - by Bioz Stars, 2026-11
    90/100 stars

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    1) Product Images from "Runx3 Induces a Cell Shape Change and Suppresses Migration and Metastasis of Melanoma Cells by Altering a Transcriptional Profile"

    Article Title: Runx3 Induces a Cell Shape Change and Suppresses Migration and Metastasis of Melanoma Cells by Altering a Transcriptional Profile

    Journal: International Journal of Molecular Sciences

    doi: 10.3390/ijms22042219

    Microarray analysis uncovered an altered and specific transcriptional profile underlying the cell shape change and the suppression of the metastatic potential by Runx3. ( A ) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations assigned different repertoires of differentially expressed genes (DEGs) that were regulated by Runx3 in B16-F10 cells and, in the case of B16-F0 cells vs. B16-F10 cells, to the terms relevant to the actin cytoskeleton and adhesion. Each GO/KEGG annotation term is inscribed as a caption. The number of DEGs within a repertoire is described at x axis. The columns for the downregulated and the upregulated DEGs are shown in different colors as explained at the top of the figure., Down/Up by Runx3 indicates the appearance of DEGs in the case of B16-F10/Runx3 cells vs. mock control B16-F10 cells. Down/Up in B16-F0 indicates the appearance of DEGs in the case of B16-F0 cells vs. B16-F10 cells. Down/Up in common indicates the appearance of same DEGs in both cases. ( B ) Runx3 upregulated the expression of extracellular matrix (ECM) genes. The summary table indicates the gene names and their corresponding fold changes. ( C ) Runx3 regulated the expression of a list of DEGs that were inversely associated with an increase in the metastatic potential of B16-F10 cells compared to B16-F0 cells. The heatmap shows the gene names and their fold changes in the cases of B16-F10/Runx3 cells vs. mock control B16-F10 cells and B16-F0 cells vs. B16-F10 cells, respectively.
    Figure Legend Snippet: Microarray analysis uncovered an altered and specific transcriptional profile underlying the cell shape change and the suppression of the metastatic potential by Runx3. ( A ) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations assigned different repertoires of differentially expressed genes (DEGs) that were regulated by Runx3 in B16-F10 cells and, in the case of B16-F0 cells vs. B16-F10 cells, to the terms relevant to the actin cytoskeleton and adhesion. Each GO/KEGG annotation term is inscribed as a caption. The number of DEGs within a repertoire is described at x axis. The columns for the downregulated and the upregulated DEGs are shown in different colors as explained at the top of the figure., Down/Up by Runx3 indicates the appearance of DEGs in the case of B16-F10/Runx3 cells vs. mock control B16-F10 cells. Down/Up in B16-F0 indicates the appearance of DEGs in the case of B16-F0 cells vs. B16-F10 cells. Down/Up in common indicates the appearance of same DEGs in both cases. ( B ) Runx3 upregulated the expression of extracellular matrix (ECM) genes. The summary table indicates the gene names and their corresponding fold changes. ( C ) Runx3 regulated the expression of a list of DEGs that were inversely associated with an increase in the metastatic potential of B16-F10 cells compared to B16-F0 cells. The heatmap shows the gene names and their fold changes in the cases of B16-F10/Runx3 cells vs. mock control B16-F10 cells and B16-F0 cells vs. B16-F10 cells, respectively.

    Techniques Used: Microarray, Control, Expressing

    Related Articles

    Microarray:

    Article Title: Runx3 Induces a Cell Shape Change and Suppresses Migration and Metastasis of Melanoma Cells by Altering a Transcriptional Profile
    Article Snippet: .. SmartArray microarray chips (CapitalBio, Beijing, China) were prepared from 32K Mouse Genome Array version 4.0 ( http://www.Operon.com , accessed on 25 April 2011). .. Total RNA was prepared using Trizol reagent (15596026, Invitrogen, ThermoFisher, Waltham, MA, USA) and was purified using the NucleoSpin RNA Clean-up kit (Macherey-Nagel, Düren, Germany). cRNA was amplified and labeled with Cy5- or Cy3-dCTP using the Jingxin cRNA amplification and labeling kit (CapitalBio, Beijing, China) after the synthesis of double-stranded cDNA.



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