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smartarray chips  (CapitalBio Corporation)

 
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    CapitalBio Corporation smartarray chips
    The mouse <t>SmartArray</t> chips were hybridized with RNA derived from DAC or PBS treated EL4 cells. (A) Heatmap of some upregulated genes by DAC treatment. Columns represent microarray data obtained from 3 independent biological replicates. (B) RT-PCR was used to validate the up-regulated genes. (C) qRT-PCR was used to quantify up-regulated genes in DAC and PBS treated EL4 cells.
    Smartarray Chips, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/smartarray+chips/pmc03650049-90-0-1?v=CapitalBio+Corporation
    Average 90 stars, based on 1 article reviews
    smartarray chips - by Bioz Stars, 2026-07
    90/100 stars

    Images

    1) Product Images from "Low Dose Decitabine Treatment Induces CD80 Expression in Cancer Cells and Stimulates Tumor Specific Cytotoxic T Lymphocyte Responses"

    Article Title: Low Dose Decitabine Treatment Induces CD80 Expression in Cancer Cells and Stimulates Tumor Specific Cytotoxic T Lymphocyte Responses

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0062924

    The mouse SmartArray chips were hybridized with RNA derived from DAC or PBS treated EL4 cells. (A) Heatmap of some upregulated genes by DAC treatment. Columns represent microarray data obtained from 3 independent biological replicates. (B) RT-PCR was used to validate the up-regulated genes. (C) qRT-PCR was used to quantify up-regulated genes in DAC and PBS treated EL4 cells.
    Figure Legend Snippet: The mouse SmartArray chips were hybridized with RNA derived from DAC or PBS treated EL4 cells. (A) Heatmap of some upregulated genes by DAC treatment. Columns represent microarray data obtained from 3 independent biological replicates. (B) RT-PCR was used to validate the up-regulated genes. (C) qRT-PCR was used to quantify up-regulated genes in DAC and PBS treated EL4 cells.

    Techniques Used: Derivative Assay, Microarray, Reverse Transcription Polymerase Chain Reaction, Quantitative RT-PCR



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    <t>Microarray</t> analysis uncovered an altered and specific transcriptional profile underlying the cell shape change and the suppression of the metastatic potential by Runx3. ( A ) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations assigned different repertoires of differentially expressed genes (DEGs) that were regulated by Runx3 in B16-F10 cells and, in the case of B16-F0 cells vs. B16-F10 cells, to the terms relevant to the actin cytoskeleton and adhesion. Each GO/KEGG annotation term is inscribed as a caption. The number of DEGs within a repertoire is described at x axis. The columns for the downregulated and the upregulated DEGs are shown in different colors as explained at the top of the figure., Down/Up by Runx3 indicates the appearance of DEGs in the case of B16-F10/Runx3 cells vs. mock control B16-F10 cells. Down/Up in B16-F0 indicates the appearance of DEGs in the case of B16-F0 cells vs. B16-F10 cells. Down/Up in common indicates the appearance of same DEGs in both cases. ( B ) Runx3 upregulated the expression of extracellular matrix (ECM) genes. The summary table indicates the gene names and their corresponding fold changes. ( C ) Runx3 regulated the expression of a list of DEGs that were inversely associated with an increase in the metastatic potential of B16-F10 cells compared to B16-F0 cells. The heatmap shows the gene names and their fold changes in the cases of B16-F10/Runx3 cells vs. mock control B16-F10 cells and B16-F0 cells vs. B16-F10 cells, respectively.
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    <t>Microarray</t> analysis uncovered an altered and specific transcriptional profile underlying the cell shape change and the suppression of the metastatic potential by Runx3. ( A ) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations assigned different repertoires of differentially expressed genes (DEGs) that were regulated by Runx3 in B16-F10 cells and, in the case of B16-F0 cells vs. B16-F10 cells, to the terms relevant to the actin cytoskeleton and adhesion. Each GO/KEGG annotation term is inscribed as a caption. The number of DEGs within a repertoire is described at x axis. The columns for the downregulated and the upregulated DEGs are shown in different colors as explained at the top of the figure., Down/Up by Runx3 indicates the appearance of DEGs in the case of B16-F10/Runx3 cells vs. mock control B16-F10 cells. Down/Up in B16-F0 indicates the appearance of DEGs in the case of B16-F0 cells vs. B16-F10 cells. Down/Up in common indicates the appearance of same DEGs in both cases. ( B ) Runx3 upregulated the expression of extracellular matrix (ECM) genes. The summary table indicates the gene names and their corresponding fold changes. ( C ) Runx3 regulated the expression of a list of DEGs that were inversely associated with an increase in the metastatic potential of B16-F10 cells compared to B16-F0 cells. The heatmap shows the gene names and their fold changes in the cases of B16-F10/Runx3 cells vs. mock control B16-F10 cells and B16-F0 cells vs. B16-F10 cells, respectively.
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    The mouse <t>SmartArray</t> chips were hybridized with RNA derived from DAC or PBS treated EL4 cells. (A) Heatmap of some upregulated genes by DAC treatment. Columns represent microarray data obtained from 3 independent biological replicates. (B) RT-PCR was used to validate the up-regulated genes. (C) qRT-PCR was used to quantify up-regulated genes in DAC and PBS treated EL4 cells.
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    Image Search Results


    Microarray analysis uncovered an altered and specific transcriptional profile underlying the cell shape change and the suppression of the metastatic potential by Runx3. ( A ) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations assigned different repertoires of differentially expressed genes (DEGs) that were regulated by Runx3 in B16-F10 cells and, in the case of B16-F0 cells vs. B16-F10 cells, to the terms relevant to the actin cytoskeleton and adhesion. Each GO/KEGG annotation term is inscribed as a caption. The number of DEGs within a repertoire is described at x axis. The columns for the downregulated and the upregulated DEGs are shown in different colors as explained at the top of the figure., Down/Up by Runx3 indicates the appearance of DEGs in the case of B16-F10/Runx3 cells vs. mock control B16-F10 cells. Down/Up in B16-F0 indicates the appearance of DEGs in the case of B16-F0 cells vs. B16-F10 cells. Down/Up in common indicates the appearance of same DEGs in both cases. ( B ) Runx3 upregulated the expression of extracellular matrix (ECM) genes. The summary table indicates the gene names and their corresponding fold changes. ( C ) Runx3 regulated the expression of a list of DEGs that were inversely associated with an increase in the metastatic potential of B16-F10 cells compared to B16-F0 cells. The heatmap shows the gene names and their fold changes in the cases of B16-F10/Runx3 cells vs. mock control B16-F10 cells and B16-F0 cells vs. B16-F10 cells, respectively.

    Journal: International Journal of Molecular Sciences

    Article Title: Runx3 Induces a Cell Shape Change and Suppresses Migration and Metastasis of Melanoma Cells by Altering a Transcriptional Profile

    doi: 10.3390/ijms22042219

    Figure Lengend Snippet: Microarray analysis uncovered an altered and specific transcriptional profile underlying the cell shape change and the suppression of the metastatic potential by Runx3. ( A ) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations assigned different repertoires of differentially expressed genes (DEGs) that were regulated by Runx3 in B16-F10 cells and, in the case of B16-F0 cells vs. B16-F10 cells, to the terms relevant to the actin cytoskeleton and adhesion. Each GO/KEGG annotation term is inscribed as a caption. The number of DEGs within a repertoire is described at x axis. The columns for the downregulated and the upregulated DEGs are shown in different colors as explained at the top of the figure., Down/Up by Runx3 indicates the appearance of DEGs in the case of B16-F10/Runx3 cells vs. mock control B16-F10 cells. Down/Up in B16-F0 indicates the appearance of DEGs in the case of B16-F0 cells vs. B16-F10 cells. Down/Up in common indicates the appearance of same DEGs in both cases. ( B ) Runx3 upregulated the expression of extracellular matrix (ECM) genes. The summary table indicates the gene names and their corresponding fold changes. ( C ) Runx3 regulated the expression of a list of DEGs that were inversely associated with an increase in the metastatic potential of B16-F10 cells compared to B16-F0 cells. The heatmap shows the gene names and their fold changes in the cases of B16-F10/Runx3 cells vs. mock control B16-F10 cells and B16-F0 cells vs. B16-F10 cells, respectively.

    Article Snippet: SmartArray microarray chips (CapitalBio, Beijing, China) were prepared from 32K Mouse Genome Array version 4.0 ( http://www.Operon.com , accessed on 25 April 2011).

    Techniques: Microarray, Control, Expressing

    The mouse SmartArray chips were hybridized with RNA derived from DAC or PBS treated EL4 cells. (A) Heatmap of some upregulated genes by DAC treatment. Columns represent microarray data obtained from 3 independent biological replicates. (B) RT-PCR was used to validate the up-regulated genes. (C) qRT-PCR was used to quantify up-regulated genes in DAC and PBS treated EL4 cells.

    Journal: PLoS ONE

    Article Title: Low Dose Decitabine Treatment Induces CD80 Expression in Cancer Cells and Stimulates Tumor Specific Cytotoxic T Lymphocyte Responses

    doi: 10.1371/journal.pone.0062924

    Figure Lengend Snippet: The mouse SmartArray chips were hybridized with RNA derived from DAC or PBS treated EL4 cells. (A) Heatmap of some upregulated genes by DAC treatment. Columns represent microarray data obtained from 3 independent biological replicates. (B) RT-PCR was used to validate the up-regulated genes. (C) qRT-PCR was used to quantify up-regulated genes in DAC and PBS treated EL4 cells.

    Article Snippet: SmartArray (CapitalBio, Beijing, China) chips containing about 25000 mouse genes were hybridized with labeled cDNA probes on a GeneChip system.

    Techniques: Derivative Assay, Microarray, Reverse Transcription Polymerase Chain Reaction, Quantitative RT-PCR