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Advanced Instruments Inc 3250 single-sample osmometer
3250 Single Sample Osmometer, supplied by Advanced Instruments Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/single-sample+osmometer/3250+single+sample+osmometer/pm40197832-94-8-11
Average 90 stars, based on 1 article reviews
3250 single-sample osmometer - by Bioz Stars, 2026-10
90/100 stars

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Related Articles

Sampling:

Article Title: Development of an HEK293 Suspension Cell Culture Medium, Transient Transfection Optimization Workflow, and Analytics for Batch rAAV Manufacturing.
Article Snippet: Osmolarity of media formulations was measured using a 3250 Single‐Sample Osmometer (Advanced Instruments).

Article Title: Exercise-Induced Hyponatremia: An Assessment of the International Hydration Recommendations Followed During the Gran Trail De Peñalara and Vitoria-Gasteiz Ironman Competitions
Article Snippet: In all GTP finishers, and in a random sampling of 18 VGI finishers pre and post-race analysis of the following additional parameters was also performed: Hb, Hematocrit, leukocytes, serum urea and creatinine (Sysmex Xe-2100 analyzer) Plasma Osmolality (POsm) and Urine Osmolality (UOsm; Advanced Instruments 3300 osmometer), urine electrolytes (Beckman Coulter AU5800 analyzer), serum Copeptin (enzyme immunoassay using Cloud Clone reagents), and serum Pro-BNP (immunoluminescence using a Roche Elecsys E-170).

Article Title: Extracellular fluid viscosity regulates human mesenchymal stem cell lineage and function
Article Snippet: The osmolarity of the adipogenic/osteogenic induction medium at either 0.77 or 8 cP was measured by using a 3205 Single-Sample Osmometer (Advanced Instruments) (fig. S1A).

Article Title: Blood, Sweat, and Tears: Implications for Hydration Testing in Combat Sports-Investigating Body Mass Loss and Biomarker Changes.
Article Snippet: The serum was separated, and osmolality (Advanced 3250 single- sample osmometer; Advanced Instruments) was assessed.

Article Title: Controlling monoclonal antibody aggregation during cell culture using medium additives facilitated by the monitoring of aggregation in cell culture matrix using size exclusion chromatography.
Article Snippet: Controlling monoclonal antibody aggregation at the upstream stage itself can significantly reduce the burden on downstream processing and can improve the process yield.. Hence, we have investigated the use of sugar osmolytes (glucose, mannose, sucrose and maltose) and formulation excipients (mannitol, polysorbate 20 and polysorbate 80) as medium additives to reduce protein aggregation during cell culture.. Aggregate content in cell culture samples was estimated using a high-resolution size-exclusion chromatography technique, which efficiently resolved the antibody monomer and aggregates in the cell culture matrix i.e., without purification.

Article Title: Extracellular fluid viscosity enhances cell migration and cancer dissemination
Article Snippet: Osmolarity was measured using freezing-point depression with a 3205 Single-Sample Osmometer (Advanced Instruments).

Clinical Proteomics:

Article Title: Development of an HEK293 Suspension Cell Culture Medium, Transient Transfection Optimization Workflow, and Analytics for Batch rAAV Manufacturing.
Article Snippet: Osmolarity of media formulations was measured using a 3250 Single‐Sample Osmometer (Advanced Instruments).

Article Title: Exercise-Induced Hyponatremia: An Assessment of the International Hydration Recommendations Followed During the Gran Trail De Peñalara and Vitoria-Gasteiz Ironman Competitions
Article Snippet: In all GTP finishers, and in a random sampling of 18 VGI finishers pre and post-race analysis of the following additional parameters was also performed: Hb, Hematocrit, leukocytes, serum urea and creatinine (Sysmex Xe-2100 analyzer) Plasma Osmolality (POsm) and Urine Osmolality (UOsm; Advanced Instruments 3300 osmometer), urine electrolytes (Beckman Coulter AU5800 analyzer), serum Copeptin (enzyme immunoassay using Cloud Clone reagents), and serum Pro-BNP (immunoluminescence using a Roche Elecsys E-170).

Article Title: Extracellular fluid viscosity regulates human mesenchymal stem cell lineage and function
Article Snippet: The osmolarity of the adipogenic/osteogenic induction medium at either 0.77 or 8 cP was measured by using a 3205 Single-Sample Osmometer (Advanced Instruments) (fig. S1A).

Article Title: Blood, Sweat, and Tears: Implications for Hydration Testing in Combat Sports-Investigating Body Mass Loss and Biomarker Changes.
Article Snippet: The serum was separated, and osmolality (Advanced 3250 single- sample osmometer; Advanced Instruments) was assessed.

Article Title: Controlling monoclonal antibody aggregation during cell culture using medium additives facilitated by the monitoring of aggregation in cell culture matrix using size exclusion chromatography.
Article Snippet: Controlling monoclonal antibody aggregation at the upstream stage itself can significantly reduce the burden on downstream processing and can improve the process yield.. Hence, we have investigated the use of sugar osmolytes (glucose, mannose, sucrose and maltose) and formulation excipients (mannitol, polysorbate 20 and polysorbate 80) as medium additives to reduce protein aggregation during cell culture.. Aggregate content in cell culture samples was estimated using a high-resolution size-exclusion chromatography technique, which efficiently resolved the antibody monomer and aggregates in the cell culture matrix i.e., without purification.

Article Title: Extracellular fluid viscosity enhances cell migration and cancer dissemination
Article Snippet: Osmolarity was measured using freezing-point depression with a 3205 Single-Sample Osmometer (Advanced Instruments).

Enzyme-linked Immunosorbent Assay:

Article Title: Development of an HEK293 Suspension Cell Culture Medium, Transient Transfection Optimization Workflow, and Analytics for Batch rAAV Manufacturing.
Article Snippet: Osmolarity of media formulations was measured using a 3250 Single‐Sample Osmometer (Advanced Instruments).

Article Title: Exercise-Induced Hyponatremia: An Assessment of the International Hydration Recommendations Followed During the Gran Trail De Peñalara and Vitoria-Gasteiz Ironman Competitions
Article Snippet: In all GTP finishers, and in a random sampling of 18 VGI finishers pre and post-race analysis of the following additional parameters was also performed: Hb, Hematocrit, leukocytes, serum urea and creatinine (Sysmex Xe-2100 analyzer) Plasma Osmolality (POsm) and Urine Osmolality (UOsm; Advanced Instruments 3300 osmometer), urine electrolytes (Beckman Coulter AU5800 analyzer), serum Copeptin (enzyme immunoassay using Cloud Clone reagents), and serum Pro-BNP (immunoluminescence using a Roche Elecsys E-170).

Article Title: Extracellular fluid viscosity regulates human mesenchymal stem cell lineage and function
Article Snippet: The osmolarity of the adipogenic/osteogenic induction medium at either 0.77 or 8 cP was measured by using a 3205 Single-Sample Osmometer (Advanced Instruments) (fig. S1A).

Article Title: Blood, Sweat, and Tears: Implications for Hydration Testing in Combat Sports-Investigating Body Mass Loss and Biomarker Changes.
Article Snippet: The serum was separated, and osmolality (Advanced 3250 single- sample osmometer; Advanced Instruments) was assessed.

Article Title: Controlling monoclonal antibody aggregation during cell culture using medium additives facilitated by the monitoring of aggregation in cell culture matrix using size exclusion chromatography.
Article Snippet: Controlling monoclonal antibody aggregation at the upstream stage itself can significantly reduce the burden on downstream processing and can improve the process yield.. Hence, we have investigated the use of sugar osmolytes (glucose, mannose, sucrose and maltose) and formulation excipients (mannitol, polysorbate 20 and polysorbate 80) as medium additives to reduce protein aggregation during cell culture.. Aggregate content in cell culture samples was estimated using a high-resolution size-exclusion chromatography technique, which efficiently resolved the antibody monomer and aggregates in the cell culture matrix i.e., without purification.

Article Title: Extracellular fluid viscosity enhances cell migration and cancer dissemination
Article Snippet: Osmolarity was measured using freezing-point depression with a 3205 Single-Sample Osmometer (Advanced Instruments).

Selection:

Article Title: Development of an HEK293 Suspension Cell Culture Medium, Transient Transfection Optimization Workflow, and Analytics for Batch rAAV Manufacturing.
Article Snippet: Osmolarity of media formulations was measured using a 3250 Single‐Sample Osmometer (Advanced Instruments).

Article Title: Exercise-Induced Hyponatremia: An Assessment of the International Hydration Recommendations Followed During the Gran Trail De Peñalara and Vitoria-Gasteiz Ironman Competitions
Article Snippet: In all GTP finishers, and in a random sampling of 18 VGI finishers pre and post-race analysis of the following additional parameters was also performed: Hb, Hematocrit, leukocytes, serum urea and creatinine (Sysmex Xe-2100 analyzer) Plasma Osmolality (POsm) and Urine Osmolality (UOsm; Advanced Instruments 3300 osmometer), urine electrolytes (Beckman Coulter AU5800 analyzer), serum Copeptin (enzyme immunoassay using Cloud Clone reagents), and serum Pro-BNP (immunoluminescence using a Roche Elecsys E-170).

Article Title: Extracellular fluid viscosity regulates human mesenchymal stem cell lineage and function
Article Snippet: The osmolarity of the adipogenic/osteogenic induction medium at either 0.77 or 8 cP was measured by using a 3205 Single-Sample Osmometer (Advanced Instruments) (fig. S1A).

Article Title: Blood, Sweat, and Tears: Implications for Hydration Testing in Combat Sports-Investigating Body Mass Loss and Biomarker Changes.
Article Snippet: The serum was separated, and osmolality (Advanced 3250 single- sample osmometer; Advanced Instruments) was assessed.

Article Title: Controlling monoclonal antibody aggregation during cell culture using medium additives facilitated by the monitoring of aggregation in cell culture matrix using size exclusion chromatography.
Article Snippet: Controlling monoclonal antibody aggregation at the upstream stage itself can significantly reduce the burden on downstream processing and can improve the process yield.. Hence, we have investigated the use of sugar osmolytes (glucose, mannose, sucrose and maltose) and formulation excipients (mannitol, polysorbate 20 and polysorbate 80) as medium additives to reduce protein aggregation during cell culture.. Aggregate content in cell culture samples was estimated using a high-resolution size-exclusion chromatography technique, which efficiently resolved the antibody monomer and aggregates in the cell culture matrix i.e., without purification.

Article Title: Extracellular fluid viscosity enhances cell migration and cancer dissemination
Article Snippet: Osmolarity was measured using freezing-point depression with a 3205 Single-Sample Osmometer (Advanced Instruments).



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At baseline, R607H KI/KI and L919X KI/KI mice exhibit alkaline urine and decreased urinary ammonium secretion. (A-F) Urinary pH (A), ammonium/creatine ratio (B), <t>osmolality</t> (C), sodium/creatinine ratio (D), chloride/creatinine ratio (E) and potassium/creatinine ratio (F) comparison between WT and L919X KI/KI mice. (G-L) Urinary pH (G), ammonium/creatine ratio (H), osmolality (I), sodium/creatinine ratio (J), chloride/creatinine ratio (K) and potassium/creatinine ratio (L) comparison between WT and R607H KI/KI mice. Error bars correspond to means±s.e.m. ** P <0.01, **** P <0.0001 using unpaired two-tailed Student's t -test or Mann–Whitney test. Note that the large sample size is due to the analysis of baseline urine samples from all experiments, resulting in 34-37 samples for WT and 35-39 samples for KI mice.
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Image Search Results


At baseline, R607H KI/KI and L919X KI/KI mice exhibit alkaline urine and decreased urinary ammonium secretion. (A-F) Urinary pH (A), ammonium/creatine ratio (B), osmolality (C), sodium/creatinine ratio (D), chloride/creatinine ratio (E) and potassium/creatinine ratio (F) comparison between WT and L919X KI/KI mice. (G-L) Urinary pH (G), ammonium/creatine ratio (H), osmolality (I), sodium/creatinine ratio (J), chloride/creatinine ratio (K) and potassium/creatinine ratio (L) comparison between WT and R607H KI/KI mice. Error bars correspond to means±s.e.m. ** P <0.01, **** P <0.0001 using unpaired two-tailed Student's t -test or Mann–Whitney test. Note that the large sample size is due to the analysis of baseline urine samples from all experiments, resulting in 34-37 samples for WT and 35-39 samples for KI mice.

Journal: Disease Models & Mechanisms

Article Title: Urinary sodium wasting and disrupted collecting duct function in mice with distal renal tubular acidosis mutations

doi: 10.1242/dmm.052138

Figure Lengend Snippet: At baseline, R607H KI/KI and L919X KI/KI mice exhibit alkaline urine and decreased urinary ammonium secretion. (A-F) Urinary pH (A), ammonium/creatine ratio (B), osmolality (C), sodium/creatinine ratio (D), chloride/creatinine ratio (E) and potassium/creatinine ratio (F) comparison between WT and L919X KI/KI mice. (G-L) Urinary pH (G), ammonium/creatine ratio (H), osmolality (I), sodium/creatinine ratio (J), chloride/creatinine ratio (K) and potassium/creatinine ratio (L) comparison between WT and R607H KI/KI mice. Error bars correspond to means±s.e.m. ** P <0.01, **** P <0.0001 using unpaired two-tailed Student's t -test or Mann–Whitney test. Note that the large sample size is due to the analysis of baseline urine samples from all experiments, resulting in 34-37 samples for WT and 35-39 samples for KI mice.

Article Snippet: Urine osmolality was measured with the Advanced Instruments Osmo1 Single-Sample Micro-Osmometer (Thermo Fisher Scientific), diluting samples at 1:10 or 1:100 with filtered ddH 2 O. Urine electrolytes were measured by ion chromatography (Dionex Aquion Ion Chromatography System, Thermo Fisher Scientific) with an autosampler.

Techniques: Comparison, Two Tailed Test, MANN-WHITNEY

After a salt-depleted acid diet, R607H KI/KI mice and L919X KI/KI mice are hypernatremic and hyperchloremic. (A,B) Plasma sodium (A) and chloride (B) concentrations from L919X KI/KI mice or WT littermates. (C) Renin gene expression in L919X KI/KI mice or WT littermates. (D,E) Urine osmolality (D) and water consumed (E) by L919X KI/KI mice or WT littermates over the 14-day time course of the diet. BW, body weight. (F,G) Plasma sodium (F) and chloride (G) concentrations from R607H KI/KI mice or WT littermates. (H) Renin gene expression in R607H KI/KI mice or WT littermates. (I,J) Urine osmolality (I) and water consumed (J) by R607H KI/KI mice or WT littermates over the 14-day time course of the diet. Error bars correspond to means±s.e.m. * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001 using unpaired two-tailed Student's t -test or two-way ANOVA with Tukey's multiple comparison test.

Journal: Disease Models & Mechanisms

Article Title: Urinary sodium wasting and disrupted collecting duct function in mice with distal renal tubular acidosis mutations

doi: 10.1242/dmm.052138

Figure Lengend Snippet: After a salt-depleted acid diet, R607H KI/KI mice and L919X KI/KI mice are hypernatremic and hyperchloremic. (A,B) Plasma sodium (A) and chloride (B) concentrations from L919X KI/KI mice or WT littermates. (C) Renin gene expression in L919X KI/KI mice or WT littermates. (D,E) Urine osmolality (D) and water consumed (E) by L919X KI/KI mice or WT littermates over the 14-day time course of the diet. BW, body weight. (F,G) Plasma sodium (F) and chloride (G) concentrations from R607H KI/KI mice or WT littermates. (H) Renin gene expression in R607H KI/KI mice or WT littermates. (I,J) Urine osmolality (I) and water consumed (J) by R607H KI/KI mice or WT littermates over the 14-day time course of the diet. Error bars correspond to means±s.e.m. * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001 using unpaired two-tailed Student's t -test or two-way ANOVA with Tukey's multiple comparison test.

Article Snippet: Urine osmolality was measured with the Advanced Instruments Osmo1 Single-Sample Micro-Osmometer (Thermo Fisher Scientific), diluting samples at 1:10 or 1:100 with filtered ddH 2 O. Urine electrolytes were measured by ion chromatography (Dionex Aquion Ion Chromatography System, Thermo Fisher Scientific) with an autosampler.

Techniques: Clinical Proteomics, Gene Expression, Two Tailed Test, Comparison