simulated physiological fluids (International Pharmacopoeia)
90
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International Pharmacopoeia
simulated physiological fluids
Simulated Physiological Fluids, supplied by International Pharmacopoeia, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/simulated+physiological+fluids/us+pharmacopeia+simulated+intestinal+fluid+ts++without+pancreatin+/pm23462963-94-0-7
Average 90 stars, based on 1 article reviews
Simulated Physiological Fluids, supplied by International Pharmacopoeia, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/simulated+physiological+fluids/us+pharmacopeia+simulated+intestinal+fluid+ts++without+pancreatin+/pm23462963-94-0-7
Average 90 stars, based on 1 article reviews
simulated physiological fluids - by Bioz Stars,
2026-11
90/100 stars
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Comparison:Article Title: Food-grade titanium dioxide (E171) induces anxiety, adenomas in colon and goblet cells hyperplasia in a regular diet model and microvesicular steatosis in a high fat diet model. Article Snippet: Please cite this article as: Medina-Reyes, E.I., Delgado-Buenrostro, N.L., Díaz-Urbina, D., RodríguezIbarra, C., Déciga-Alcaraz, A., González, M.I., Reyes, J.L., Villamar-Duque, T.E., Flores-Sánchez, M.L., Hernández-Pando, R., Mancilla-Díaz, J.M., Chirino, Y.I., Pedraza-Chaverri, J., Food-grade titanium dioxide (E171) induces anxiety, adenomas in colon and goblet cells hyperplasia in a regular diet model and microvesicular steatosis in a high fat diet model, Food and Chemical Toxicology, https:// doi.org/10.1016/j.fct.2020.111786. Article Title: Formation of celecoxib nanoparticles from volatile microemulsions. Article Snippet: A new composition of a fully water-dilutable microemulsion system stabilized by natural surfactants is presented as a template for preparation of celecoxib nanoparticles.. Nanoparticles are obtained as a dry powder upon rapid conversion of microemulsion droplets with dissolved celecoxib into nanoparticles, followed by evaporation of all the liquid in a spray dryer.. The resultant powder is easily re-dispersible vailable online 18 April 2010 Article Title: Acidic and basic drugs in medicinal chemistry: a perspective. Article Snippet: The acid/base properties of a molecule are among the most fundamental for drug action.. However, they are often overlooked in a prospective design manner unless it has been established that a certain ionization state (e.g., quaternary base or presence of a carboxylic acid) appears to be required for activity.. In medicinal chemistry optimization programs it is relatively common to attenuate basicity to circumvent undesired effects such as lack of biological selectivity or safety risks such as hERG or phospholipidosis. Article Title: Ternary Amorphous Solid Dispersions Containing a High-Viscosity Polymer and Mesoporous Silica Enhance Dissolution Performance†. Article Snippet: The aim of this study was to evaluate the benefits of a ternary amorphous solid dispersion (ASD) that was designed as an immediate-release tablet with a high drug load (e.g., 40% w/w) to produce heightened maintenance of drug supersaturation during dissolution testing, which will be henceforth referred to as the “maintenance ability”.. Ternary ASD granules were produced by hot melt extrusion (HME) and were comprised of itraconazole (ITZ) 50%, hypromellose (HPMC) 20%, and mesoporous silica (XDP) 30%, where amorphous ITZ incorporated into HPMC was efficiently absorbed in XDP pores.. The ternary ASD granules containing a high-viscosity HPMC (AF4M) produced a significantly heightened maintenance ability of drug supersaturation in neutral pH dissolution media in which crystalline ITZ solubility is below 1 μg/mL. In Vitro:Article Title: Food-grade titanium dioxide (E171) induces anxiety, adenomas in colon and goblet cells hyperplasia in a regular diet model and microvesicular steatosis in a high fat diet model. Article Snippet: Please cite this article as: Medina-Reyes, E.I., Delgado-Buenrostro, N.L., Díaz-Urbina, D., RodríguezIbarra, C., Déciga-Alcaraz, A., González, M.I., Reyes, J.L., Villamar-Duque, T.E., Flores-Sánchez, M.L., Hernández-Pando, R., Mancilla-Díaz, J.M., Chirino, Y.I., Pedraza-Chaverri, J., Food-grade titanium dioxide (E171) induces anxiety, adenomas in colon and goblet cells hyperplasia in a regular diet model and microvesicular steatosis in a high fat diet model, Food and Chemical Toxicology, https:// doi.org/10.1016/j.fct.2020.111786. Article Title: Formation of celecoxib nanoparticles from volatile microemulsions. Article Snippet: A new composition of a fully water-dilutable microemulsion system stabilized by natural surfactants is presented as a template for preparation of celecoxib nanoparticles.. Nanoparticles are obtained as a dry powder upon rapid conversion of microemulsion droplets with dissolved celecoxib into nanoparticles, followed by evaporation of all the liquid in a spray dryer.. The resultant powder is easily re-dispersible vailable online 18 April 2010 Article Title: Acidic and basic drugs in medicinal chemistry: a perspective. Article Snippet: The acid/base properties of a molecule are among the most fundamental for drug action.. However, they are often overlooked in a prospective design manner unless it has been established that a certain ionization state (e.g., quaternary base or presence of a carboxylic acid) appears to be required for activity.. In medicinal chemistry optimization programs it is relatively common to attenuate basicity to circumvent undesired effects such as lack of biological selectivity or safety risks such as hERG or phospholipidosis. Article Title: Ternary Amorphous Solid Dispersions Containing a High-Viscosity Polymer and Mesoporous Silica Enhance Dissolution Performance†. Article Snippet: The aim of this study was to evaluate the benefits of a ternary amorphous solid dispersion (ASD) that was designed as an immediate-release tablet with a high drug load (e.g., 40% w/w) to produce heightened maintenance of drug supersaturation during dissolution testing, which will be henceforth referred to as the “maintenance ability”.. Ternary ASD granules were produced by hot melt extrusion (HME) and were comprised of itraconazole (ITZ) 50%, hypromellose (HPMC) 20%, and mesoporous silica (XDP) 30%, where amorphous ITZ incorporated into HPMC was efficiently absorbed in XDP pores.. The ternary ASD granules containing a high-viscosity HPMC (AF4M) produced a significantly heightened maintenance ability of drug supersaturation in neutral pH dissolution media in which crystalline ITZ solubility is below 1 μg/mL. Dissolution:Article Title: Food-grade titanium dioxide (E171) induces anxiety, adenomas in colon and goblet cells hyperplasia in a regular diet model and microvesicular steatosis in a high fat diet model. Article Snippet: Please cite this article as: Medina-Reyes, E.I., Delgado-Buenrostro, N.L., Díaz-Urbina, D., RodríguezIbarra, C., Déciga-Alcaraz, A., González, M.I., Reyes, J.L., Villamar-Duque, T.E., Flores-Sánchez, M.L., Hernández-Pando, R., Mancilla-Díaz, J.M., Chirino, Y.I., Pedraza-Chaverri, J., Food-grade titanium dioxide (E171) induces anxiety, adenomas in colon and goblet cells hyperplasia in a regular diet model and microvesicular steatosis in a high fat diet model, Food and Chemical Toxicology, https:// doi.org/10.1016/j.fct.2020.111786. Article Title: Formation of celecoxib nanoparticles from volatile microemulsions. Article Snippet: A new composition of a fully water-dilutable microemulsion system stabilized by natural surfactants is presented as a template for preparation of celecoxib nanoparticles.. Nanoparticles are obtained as a dry powder upon rapid conversion of microemulsion droplets with dissolved celecoxib into nanoparticles, followed by evaporation of all the liquid in a spray dryer.. The resultant powder is easily re-dispersible vailable online 18 April 2010 Article Title: Acidic and basic drugs in medicinal chemistry: a perspective. Article Snippet: The acid/base properties of a molecule are among the most fundamental for drug action.. However, they are often overlooked in a prospective design manner unless it has been established that a certain ionization state (e.g., quaternary base or presence of a carboxylic acid) appears to be required for activity.. In medicinal chemistry optimization programs it is relatively common to attenuate basicity to circumvent undesired effects such as lack of biological selectivity or safety risks such as hERG or phospholipidosis. Article Title: Ternary Amorphous Solid Dispersions Containing a High-Viscosity Polymer and Mesoporous Silica Enhance Dissolution Performance†. Article Snippet: The aim of this study was to evaluate the benefits of a ternary amorphous solid dispersion (ASD) that was designed as an immediate-release tablet with a high drug load (e.g., 40% w/w) to produce heightened maintenance of drug supersaturation during dissolution testing, which will be henceforth referred to as the “maintenance ability”.. Ternary ASD granules were produced by hot melt extrusion (HME) and were comprised of itraconazole (ITZ) 50%, hypromellose (HPMC) 20%, and mesoporous silica (XDP) 30%, where amorphous ITZ incorporated into HPMC was efficiently absorbed in XDP pores.. The ternary ASD granules containing a high-viscosity HPMC (AF4M) produced a significantly heightened maintenance ability of drug supersaturation in neutral pH dissolution media in which crystalline ITZ solubility is below 1 μg/mL. other:Article Title: Toward Biopredictive Dissolution for Enteric Coated Dosage Forms. Article Snippet: 9 The aim of this work was to develop a phosphate buffer-based dissolution method for 10 enteric-coated formulations with improved biopredictivity for fasted conditions.. Two 11 commercially available enteric-coated aspirin products were used as model formulations 12 (Aspirin Protect® 300 mg, and Walgreens Aspirin®325 mg).. The disintegration performance 13 of these products in a physiological 8 mM pH 6.5 bicarbonate buffer (representing the 14 conditions in the proximal small intestine) was used as a standard to optimize the employed 15 phosphate buffer molarity. |