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marvinsketch 18.30.0  (ChemAxon LLC)

 
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    Structured Review

    ChemAxon LLC marvinsketch 18.30.0
    Physicochemical properties, blood binding and ADME parameters of BPA.
    Marvinsketch 18.30.0, supplied by ChemAxon LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/simcyp+simulator+v21/pmc10120294-5-25-28?v=ChemAxon+LLC
    Average 90 stars, based on 1 article reviews
    marvinsketch 18.30.0 - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Data on ADME parameters of bisphenol A and its metabolites for use in physiologically based pharmacokinetic modelling"

    Article Title: Data on ADME parameters of bisphenol A and its metabolites for use in physiologically based pharmacokinetic modelling

    Journal: Data in Brief

    doi: 10.1016/j.dib.2023.109101

    Physicochemical properties, blood binding and ADME parameters of BPA.
    Figure Legend Snippet: Physicochemical properties, blood binding and ADME parameters of BPA.

    Techniques Used: Binding Assay, Recombinant

    Physicochemical properties, blood and ADME parameters of BPAG and BPAS.
    Figure Legend Snippet: Physicochemical properties, blood and ADME parameters of BPAG and BPAS.

    Techniques Used: Binding Assay


    Figure Legend Snippet:

    Techniques Used: Mutagenesis, Drug discovery



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    Image Search Results


    Key PBPK modelling steps and components of each clinical study used in model development, refinement, verification and application. BCRP, breast cancer resistance protein; DDI, drug–drug interaction; fu inc , fraction of unbound dersimelagon in in vitro system; K m , Michaelis constant; MAD, multiple ascending dose; OATP, organic anion transporting polypeptide; PBPK, physiologically based pharmacokinetic; PK, pharmacokinetic; QD, once daily; V max , maximum velocity of reaction; V ss , volume of distribution at steady state.

    Journal: British Journal of Clinical Pharmacology

    Article Title: Physiologically based pharmacokinetic modelling to predict potential drug–drug interactions of dersimelagon (MT‐7117)

    doi: 10.1111/bcp.16271

    Figure Lengend Snippet: Key PBPK modelling steps and components of each clinical study used in model development, refinement, verification and application. BCRP, breast cancer resistance protein; DDI, drug–drug interaction; fu inc , fraction of unbound dersimelagon in in vitro system; K m , Michaelis constant; MAD, multiple ascending dose; OATP, organic anion transporting polypeptide; PBPK, physiologically based pharmacokinetic; PK, pharmacokinetic; QD, once daily; V max , maximum velocity of reaction; V ss , volume of distribution at steady state.

    Article Snippet: All simulations were conducted using the Simcyp PBPK Simulator v21 (Certara), which integrates demographic, physiological, genomic and in vitro biochemical data to allow prediction of PK in virtual healthy populations.

    Techniques: In Vitro

    Input parameters of the physiologically based pharmacokinetic model for dersimelagon.

    Journal: British Journal of Clinical Pharmacology

    Article Title: Physiologically based pharmacokinetic modelling to predict potential drug–drug interactions of dersimelagon (MT‐7117)

    doi: 10.1111/bcp.16271

    Figure Lengend Snippet: Input parameters of the physiologically based pharmacokinetic model for dersimelagon.

    Article Snippet: All simulations were conducted using the Simcyp PBPK Simulator v21 (Certara), which integrates demographic, physiological, genomic and in vitro biochemical data to allow prediction of PK in virtual healthy populations.

    Techniques: Binding Assay, Software, Permeability, In Vitro, Inhibition