j. biomol. tech (Biomol GmbH)
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J. Biomol. Tech, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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other:Article Title: Ion-to-Image, i2i, a Mass Spectrometry Imaging Data Analysis Platform for Continuous Ionization Techniques. Article Snippet: ■ REFERENCES (1) Caprioli, Article Title: Naked-Eye Detection of LAMP-Produced Nucleic Acids in Saliva Using Chitosan-Capped AuNPs in a Single-Tube Assay. Article Snippet: B.; Lemire, A. L.; Article Title: Visualization of Differential Cardiolipin Profiles in Murine Retinal Cell Layers by High-Resolution MALDI Mass Spectrometry Imaging. Article Snippet: The precise fatty acyl chain configuration of cardiolipin (CL), a tetrameric mitochondrial-specific membrane lipid, exhibits dependence on cell and tissue types.. A powerful method to map CL profiles in tissue sections in a spatially resolved manner is matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI).. To build on and explore this potential, we employed a quadrupole time-of-flight mass spectrometer along with optimized sample preparation protocols. Article Title: Spatiotemporally Resolved Approach for Profiling Ferroptosis-Associated Metabolic Vulnerabilities in Tumors Using Mass Spectrometry Imaging and Stable Isotope Tracing. Article Snippet: Ferroptosis, as an iron-dependent cell death mediated by lipid peroxidation, has sparked great interest in the tumor research community.. Targeting ferroptosis has been proven to be a new therapeutic opportunity for inhibiting tumor growth.. However, it is challenging to precisely characterize the metabolic pattern of ferroptosis in heterogeneous tumors and further identify ferroptosis-associated metabolic vulnerabilities for tumor treatment. Article Title: Enhancing Sensitivity in Nucleic Acid Detection via Collaborative Multiple Catalytic Cores in DNAzyme Nanomachines. Article Snippet: Nucleic acid detection stands as the cornerstone for various applications, from diagnosing infectious diseases to unravelling genetic mysteries.. Quantitative real-time polymerase chain reaction (qPCR) has long been considered as the gold standard for nucleic acid detection, particularly in diagnosing acute infections like COVID-19, by detecting viral RNA.. However, the drawbacks of qPCR, including cost constraints and long waiting times to get results, have underscored the pressing need for alternative, more accessible diagnostic methodologies. Article Title: Addressing Buffer, Size, and Clogging Challenges in LAMP-Coupled Solid-State Nanopores for Point-of-Care Testing. Article Snippet: Loop-mediated isothermal amplification (LAMP) is a promising method for point-of-care nucleic acid testing due to its simplicity, rapidity, and high sensitivity.. Coupling LAMP with solid-state nanopores enables label-free, singlemolecule sensing, enhancing diagnostic accuracy.. However, conventional LAMPcoupled nanopore protocols require high-salt buffers (>1 M) to improve signal strength and translocation frequency, complicating workflows and increasing contamination risks. Article Title: Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq. Article Snippet: [218] T. Whistler, Article Title: Nano-DESI Mass Spectrometry Imaging of Proteoforms in Biological Tissues with High Spatial Resolution. Article Snippet: Mass spectrometry imaging (MSI) is a powerful tool for label-free mapping of the spatial distribution of proteins in biological tissues.. We have previously demonstrated imaging of individual proteoforms in biological tissues using nanospray desorption electrospray ionization (nano-DESI), an ambient liquid extraction-based MSI technique.. Nano-DESI MSI generates multiply charged protein ions, which is advantageous for their identification using top-down proteomics analysis. |

