il 10 (Boster Bio)
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il 10
Il 10, supplied by Boster Bio, used in various techniques. Bioz Stars score: 97/100, based on 412 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/set/Mouse+IL-10+ELISA+Kit+EZ-Set/pmc13092712-83-2-17
Average 97 stars, based on 412 article reviews
Il 10, supplied by Boster Bio, used in various techniques. Bioz Stars score: 97/100, based on 412 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/set/Mouse+IL-10+ELISA+Kit+EZ-Set/pmc13092712-83-2-17
Average 97 stars, based on 412 article reviews
il 10 - by Bioz Stars,
2026-11
97/100 stars
Images
1) Product Images from "Exploring the role of PD-1 as a marker in drug-refractory epilepsy and its potential indication for valproic acid treatment"
Article Title: Exploring the role of PD-1 as a marker in drug-refractory epilepsy and its potential indication for valproic acid treatment
Journal: Brain, Behavior, & Immunity - Health
doi: 10.1016/j.bbih.2026.101238
Figure Legend Snippet: Elevated PD-1 expression and altered cytokine levels in plasma of IE patients. (A) PD-1 expression on CD4 + CD25 high Tregs is significantly increased in IE patients, particularly in the ISE subgroup, while CD4 + and CD4 + CD25 + T cell percentages are reduced. (B) Plasma concentrations of IL-10 and IL-6 are elevated in IE patients, with IL-10 showing a progressive increase with seizure severity. (C) Correlation analyses reveal associations between immune parameters and clinical characteristics. ∗∗∗P < 0.001, ∗∗ P < 0.01, ∗ P < 0.05; ns indicates not significant.
Techniques Used: Expressing, Clinical Proteomics
Figure Legend Snippet: Central nervous system immune activation in ISE patients. (A) PD-1 + CD4 + CD25 high Treg cell counts are significantly elevated in the CSF of ISE patients compared to controls. (B) Both IL-10 and IL-6 concentrations are increased in the CSF of ISE patients. (C) Age correlates positively with PD-1 + CD4 + CD25 low and CD4 + CD25 high Treg percentages, and negatively with CD4 + T cell percentage in the CSF of ISE patients. ∗∗∗P < 0.001, ∗∗P < 0.01, ∗P < 0.05.
Techniques Used: Activation Assay
Figure Legend Snippet: VPA treatment modulates PD-1 expression and IL-10 levels independently of drug concentration. (A) Plasma PD-1 expression on both CD4 + CD25 high and CD4 + CD25 low Treg subsets decreases significantly after 48 h of VPA treatment. (B) Plasma IL-10 levels decrease significantly after VPA treatment, while IL-6 shows no significant change. (C) Seizure control time correlates with immunological parameters but not with VPA concentrations. (D) VPA concentrations in CSF are significantly lower than in plasma, with no change between d0 and d3, and no correlation with seizure control time. ∗∗∗P < 0.001, ∗∗P < 0.01, ∗P < 0.05; ns indicates not significant.
Techniques Used: Expressing, Concentration Assay, Clinical Proteomics, Control
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