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dna methylation analysis (gene-targeted) by sequenom massarray epityper platform  (Sequenom)

 
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    Structured Review

    Sequenom dna methylation analysis (gene-targeted) by sequenom massarray epityper platform
    Summary of main projects in the PANINI network
    Dna Methylation Analysis (Gene Targeted) By Sequenom Massarray Epityper Platform, supplied by Sequenom, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sequenom+massarray+methylation+analysis/dna+methylation+analysis/pmc05968062-9-17-16
    Average 90 stars, based on 1 article reviews
    dna methylation analysis (gene-targeted) by sequenom massarray epityper platform - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Physical Activity and Nutrition INfluences In ageing (PANINI): consortium mission statement"

    Article Title: Physical Activity and Nutrition INfluences In ageing (PANINI): consortium mission statement

    Journal: Aging Clinical and Experimental Research

    doi: 10.1007/s40520-017-0823-7

    Summary of main projects in the PANINI network
    Figure Legend Snippet: Summary of main projects in the PANINI network

    Techniques Used: Battery, Activity Assay, Modification, DNA Methylation Assay, Variant Assay

    Related Articles

    DNA Methylation Assay:

    Article Title: Comparative DNA methylation among females with neurodevelopmental disorders and seizures identifies TAC1 as a MeCP2 target gene
    Article Snippet: First, we determined whether DNA methylation levels detected at specific CpG sites within the Sequenom target region validated the Illumina assay results. .. Sequenom DNA methylation levels at two CpG sites located closest to the Illumina probe were highly correlated within samples (Additional file : Figure S5). .. Next, we evaluated whether significant differential methylation occurred among clinical groups using the Sequenom CpG methylation values.

    Article Title: PTPRG inhibition By DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia
    Article Snippet: A set of 166 of pre-B ALL with RAS mutation ( KRAS and/or NRAS ) characterization and cytogenetic classifications were chosen for DNA methylation analysis using the higher density Illumina HM450K array analysis. .. Refinement and validation of these same samples was performed with Sequenom DNA methylation analysis. ..

    Article Title: Physical Activity and Nutrition INfluences In ageing (PANINI): consortium mission statement
    Article Snippet: 9. Vrije University Amsterdam , Nutrition and physical activity to counteract sarcopaenia , DEXA, BIA, food frequency questionnaire, ventilated hood , SHAPE study (geriatric outpatients with fall risk) , Muscle mass. .. 10. University of Bologna , Epigenetics of nutrition in ageing , DNA methylation analysis (gene-targeted) by Sequenom ® MassARRAY EpiTYPER platform , NU-AGE samples and new PANINI data , Changes in DNA methylation patterns induced by dietary and physical interventions. Development of a gene-targeted epigenetic clock. .. 11. Personal genomics , Genetics of nutrition in ageing , Development of a bioinformatic pipeline for the identification of Single Nucleotide Variations correlated with ageing phenotypes and response to nutritional interventions of elders. Common annotation sources will be exploited to integrate all the information available for a single variant , NU-AGE and PANINI data , List of genetic variants correlated with ageing phenotypes and nutritional interventions.

    Article Title: Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor
    Article Snippet: .. 822 hypermethylated and 43 hypomethylated statistically significant DMRs (FDR<0.05) were identified, harboring 64,005 and 623 CpG sites respectively, compared to matched normal samples (FIGS. 1A-B and Table 1) and validated sample-specific differential methylation using Sequenom DNA methylation analysis (FIG. 7). ..

    Article Title: Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value.
    Article Snippet: .. We identified 822 hypermethylated and 43 hypomethylated statistically significant DMRs (FDR o0.05), harbouring 64,005 and 623 CpG sites, respectively, compared with matched normal samples (see Fig. 1a,b; Supplementary Data 1) and validated sample-specific differential methylation using Sequenom DNA methylation analysis (Supplementary Fig. 4). ..

    Biomarker Discovery:

    Article Title: PTPRG inhibition By DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia
    Article Snippet: A set of 166 of pre-B ALL with RAS mutation ( KRAS and/or NRAS ) characterization and cytogenetic classifications were chosen for DNA methylation analysis using the higher density Illumina HM450K array analysis. .. Refinement and validation of these same samples was performed with Sequenom DNA methylation analysis. ..

    Methylation:

    Article Title: Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor
    Article Snippet: .. 822 hypermethylated and 43 hypomethylated statistically significant DMRs (FDR<0.05) were identified, harboring 64,005 and 623 CpG sites respectively, compared to matched normal samples (FIGS. 1A-B and Table 1) and validated sample-specific differential methylation using Sequenom DNA methylation analysis (FIG. 7). ..

    Article Title: Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value.
    Article Snippet: .. We identified 822 hypermethylated and 43 hypomethylated statistically significant DMRs (FDR o0.05), harbouring 64,005 and 623 CpG sites, respectively, compared with matched normal samples (see Fig. 1a,b; Supplementary Data 1) and validated sample-specific differential methylation using Sequenom DNA methylation analysis (Supplementary Fig. 4). ..

    other:

    Article Title: A Low Glycaemic Index Diet in Pregnancy Induces DNA Methylation Variation in Blood of Newborns: Results from the ROLO Randomised Controlled Trial
    Article Snippet: This may be due to the small sample size in this analysis, minor phenotypic differences in the selected sample set not accounted for in analysis, or this may potentially be due to the use of two different DNA methylation analysis techniques (Sequenom and HM850).

    Article Title: Abstracts for 32 GEER- Spanish Spine Society Congress in Avila, Spain, June 2018.
    Article Snippet: Abstracts for 32 GEERSpanish Spine Society Congress in Avila, Spain, June 2018s for 32 GEERSpanish Spine Society Congress in Avila, Spain, June 2018



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    Summary of main projects in the PANINI network

    Journal: Aging Clinical and Experimental Research

    Article Title: Physical Activity and Nutrition INfluences In ageing (PANINI): consortium mission statement

    doi: 10.1007/s40520-017-0823-7

    Figure Lengend Snippet: Summary of main projects in the PANINI network

    Article Snippet: 10. University of Bologna , Epigenetics of nutrition in ageing , DNA methylation analysis (gene-targeted) by Sequenom ® MassARRAY EpiTYPER platform , NU-AGE samples and new PANINI data , Changes in DNA methylation patterns induced by dietary and physical interventions. Development of a gene-targeted epigenetic clock.

    Techniques: Battery, Activity Assay, Modification, DNA Methylation Assay, Variant Assay