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Lawrence Livermore National Security LLC 512 processors
512 Processors, supplied by Lawrence Livermore National Security LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/security+processors/512+processors/pm30008086-281-7-14
Average 90 stars, based on 1 article reviews
512 processors - by Bioz Stars, 2026-11
90/100 stars

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Article Title: The neural γ 2 α 1 β 2 α 1 β 2 gamma amino butyric acid ion channel receptor: structural analysis of the effects of the ivermectin molecule and disulfide bridges.
Article Snippet: While~30%of thehumangenomeencodesmembraneproteins, onlyahandfulof structuresofmembraneproteinshavebeen resolved tohighresolution.Here,westudied thestructureofamemberof theCys-loopligandgated ionchannelproteinsuperfamilyof receptors, human type A γ2α1β2α1β2 gamma amino butyric acid receptor complex in a lipid bilayer environment.. Studying the correlation between the structure and functionof thegammaaminobutyric acid receptormayenhanceourunderstandingof themolecular basis of ion channel dysfunctions linkedwith epilepsy, ataxia,migraine, schizophrenia and other neurodegenerative diseases.. The structure of humanγ2α1β2α1β2 has beenmodeled based on theX-ray structure of theCaenorhabditis elegans glutamate-gated chloride channel via homologymodeling.

Article Title: Correlated conformational dynamics of the human GluN1-GluN2A type N-methyl-D-aspartate (NMDA) receptor.
Article Snippet: N-Methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels found in the nerve cell membranes.. As a result of overexcitation of NMDARs, neuronal death occurs and may lead to diseases such as epilepsy, stroke, Alzheimer’s disease, and Parkinson’s disease.. In this study, humanGluN1GluN2A type NMDAR structure is modeled based on the X-ray structure of the Xenopus laevis template and missing loops are added by ab-initio loop modeling.



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