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tcga rnaseq data  (GraphPad Software Inc)


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    Structured Review

    GraphPad Software Inc tcga rnaseq data
    High DMD expression is significantly associated with poor survival in LGG. ( a ) <t>TCGA</t> <t>RNAseq</t> data from WHO grade II LGG cases was dichotomised into high (blue) and low (red) DMD expressing groups and survival analysis performed in GraphPad using the log-rank test. Tumour subtype analysis was also performed. Numbers in brackets are median overall survival times in months. ( b ) Forest plot revealing the log-rank hazard ratio with 95% confidence intervals and number of patients for each group. A astrocytoma, OD oligodendroglioma, NOS not otherwise specified.
    Tcga Rnaseq Data, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rna-seq+data+analysis+software/tcga+rnaseq+data/pmc08881458-49-16-41
    Average 90 stars, based on 1 article reviews
    tcga rnaseq data - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Duchenne muscular dystrophy gene expression is an independent prognostic marker for IDH mutant low-grade glioma"

    Article Title: Duchenne muscular dystrophy gene expression is an independent prognostic marker for IDH mutant low-grade glioma

    Journal: Scientific Reports

    doi: 10.1038/s41598-022-07223-2

    High DMD expression is significantly associated with poor survival in LGG. ( a ) TCGA RNAseq data from WHO grade II LGG cases was dichotomised into high (blue) and low (red) DMD expressing groups and survival analysis performed in GraphPad using the log-rank test. Tumour subtype analysis was also performed. Numbers in brackets are median overall survival times in months. ( b ) Forest plot revealing the log-rank hazard ratio with 95% confidence intervals and number of patients for each group. A astrocytoma, OD oligodendroglioma, NOS not otherwise specified.
    Figure Legend Snippet: High DMD expression is significantly associated with poor survival in LGG. ( a ) TCGA RNAseq data from WHO grade II LGG cases was dichotomised into high (blue) and low (red) DMD expressing groups and survival analysis performed in GraphPad using the log-rank test. Tumour subtype analysis was also performed. Numbers in brackets are median overall survival times in months. ( b ) Forest plot revealing the log-rank hazard ratio with 95% confidence intervals and number of patients for each group. A astrocytoma, OD oligodendroglioma, NOS not otherwise specified.

    Techniques Used: Expressing

    WGCNA of the TCGA WHO grade II LGG dataset identified a network of 882 genes divided into five co-expression modules. ( a ) Gene dendrogram. Colours are randomly assigned except grey which represents areas unassigned to a module. ( b ) Networks of the top 20 genes for the entire network and each module individually. ( c ) Visualisation of the GO enrichment analysis for each module; heatmap was produced in GraphPad. ( d ) Venn analysis to identify common genes returned by both WGCNA and DEG analysis.
    Figure Legend Snippet: WGCNA of the TCGA WHO grade II LGG dataset identified a network of 882 genes divided into five co-expression modules. ( a ) Gene dendrogram. Colours are randomly assigned except grey which represents areas unassigned to a module. ( b ) Networks of the top 20 genes for the entire network and each module individually. ( c ) Visualisation of the GO enrichment analysis for each module; heatmap was produced in GraphPad. ( d ) Venn analysis to identify common genes returned by both WGCNA and DEG analysis.

    Techniques Used: Expressing, Produced

    The expression of multiple DMD gene products are significantly associated with LGG survival outcomes. ( a ) LGG TCGA RNAseq data for each DMD isoform was dichotomised into high (blue) and low (red) expression groups and survival analysis performed in GraphPad using the log-rank test. Numbers in brackets are median overall survival times in months. ( b ) Kaplan–Meier survival curves for high (blue) vs low (red) Dp71, Dp71ab or Dp427m expression for each IDH mutation status group were compared. Numbers in brackets are median overall survival times in months. The tables provide the log-rank test P values for each planned comparison; the alpha value was adjusted to 0.017 to correct for multiple testing.
    Figure Legend Snippet: The expression of multiple DMD gene products are significantly associated with LGG survival outcomes. ( a ) LGG TCGA RNAseq data for each DMD isoform was dichotomised into high (blue) and low (red) expression groups and survival analysis performed in GraphPad using the log-rank test. Numbers in brackets are median overall survival times in months. ( b ) Kaplan–Meier survival curves for high (blue) vs low (red) Dp71, Dp71ab or Dp427m expression for each IDH mutation status group were compared. Numbers in brackets are median overall survival times in months. The tables provide the log-rank test P values for each planned comparison; the alpha value was adjusted to 0.017 to correct for multiple testing.

    Techniques Used: Expressing, Mutagenesis, Comparison

    Related Articles

    Expressing:

    Article Title: Duchenne muscular dystrophy gene expression is an independent prognostic marker for IDH mutant low-grade glioma
    Article Snippet: .. Figure 1 High DMD expression is significantly associated with poor survival in LGG. ( a ) TCGA RNAseq data from WHO grade II LGG cases was dichotomised into high (blue) and low (red) DMD expressing groups and survival analysis performed in GraphPad using the log-rank test. ..

    RNA sequencing:

    Article Title: Duchenne muscular dystrophy gene expression is an independent prognostic marker for IDH mutant low-grade glioma
    Article Snippet: .. Figure 1 High DMD expression is significantly associated with poor survival in LGG. ( a ) TCGA RNAseq data from WHO grade II LGG cases was dichotomised into high (blue) and low (red) DMD expressing groups and survival analysis performed in GraphPad using the log-rank test. ..



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    Key Resource Table
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    Genes Encoding Key Regulators of Antiviral Pathways Are Upregulated in Established Tumors (A) Schema for whole-exome sequencing of CT26WT cells cultured with or without 100 U/mL IFNα 2 or from established tumors. <t>RNA</t> was isolated and sent for Illumina <t>RNA</t> <t>sequencing.</t> (B) Heatmap comparing 58 interferon-stimulated genes and inflammatory genes generated using the average FPKM of two independent samples, clustered according to average linkage and Euclidean distance. (C) Log 2 (fold change) of gene expression in the 58-gene panel comparing the IFN-treated cells and tumor cells with the untreated CT26WT in vitro .
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    Image Search Results


    Key Resource Table

    Journal: Molecular cell

    Article Title: Transcriptional responses to IFN-γ require Mediator kinase-dependent pause release and mechanistically distinct functions of CDK8 and CDK19

    doi: 10.1016/j.molcel.2019.07.034

    Figure Lengend Snippet: Key Resource Table

    Article Snippet: Mix2 RNA-Seq data analysis software , Lexogen , .

    Techniques: Virus, Recombinant, Transfection, Protease Inhibitor, Reverse Transcription, Isolation, Lysis, Gel Extraction, Plasmid Preparation, Western Blot, Expressing, Cloning, Software

    Genes Encoding Key Regulators of Antiviral Pathways Are Upregulated in Established Tumors (A) Schema for whole-exome sequencing of CT26WT cells cultured with or without 100 U/mL IFNα 2 or from established tumors. RNA was isolated and sent for Illumina RNA sequencing. (B) Heatmap comparing 58 interferon-stimulated genes and inflammatory genes generated using the average FPKM of two independent samples, clustered according to average linkage and Euclidean distance. (C) Log 2 (fold change) of gene expression in the 58-gene panel comparing the IFN-treated cells and tumor cells with the untreated CT26WT in vitro .

    Journal: Molecular Therapy Oncolytics

    Article Title: Collateral Lethal Effects of Complementary Oncolytic Viruses

    doi: 10.1016/j.omto.2020.06.017

    Figure Lengend Snippet: Genes Encoding Key Regulators of Antiviral Pathways Are Upregulated in Established Tumors (A) Schema for whole-exome sequencing of CT26WT cells cultured with or without 100 U/mL IFNα 2 or from established tumors. RNA was isolated and sent for Illumina RNA sequencing. (B) Heatmap comparing 58 interferon-stimulated genes and inflammatory genes generated using the average FPKM of two independent samples, clustered according to average linkage and Euclidean distance. (C) Log 2 (fold change) of gene expression in the 58-gene panel comparing the IFN-treated cells and tumor cells with the untreated CT26WT in vitro .

    Article Snippet: AIR: RNA-Seq data analysis software (Sequentia Biotech, Barcelona, Spain) was used to generate differential gene expression analysis based on the negative binomial distribution to generate fragments per kilobase of transcript per million mapped reads (FPKM) for each condition as previously described.

    Techniques: Sequencing, Cell Culture, Isolation, RNA Sequencing Assay, Generated, Expressing, In Vitro