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mouse mrna & lncrna epitranscriptomic microarray  (Arraystar inc)

 
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    Arraystar inc mouse mrna & lncrna epitranscriptomic microarray
    Mouse Mrna & Lncrna Epitranscriptomic Microarray, supplied by Arraystar inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rna+microarray/mouse+rna+epi+transcriptomic+microarray/pm36945110-265-8-15
    Average 90 stars, based on 1 article reviews
    mouse mrna & lncrna epitranscriptomic microarray - by Bioz Stars, 2026-11
    90/100 stars

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    Related Articles

    other:

    Article Title: Epitranscriptomic Analysis of the Ventral Hippocampus in a Mouse Model of Post-Traumatic Stress Disorder Following Deep Brain Stimulation Treatment of the Basolateral Amygdala.
    Article Snippet: The amalgamated labeled cRNAs were then hybridized onto the Arraystar Mouse mRNA & lncRNA Epitranscriptomic Microarray (8 × 60K, Arraystar, Rockville, MD, USA).

    Article Title: METTL3-m6A methylation inhibits the proliferation and viability of type II alveolar epithelial cells in acute lung injury by enhancing the stability and translation efficiency of Pten mRNA.
    Article Snippet: These cRNAs were subsequently combined and hybridized onto the Arraystar Mouse mRNA&lncRNA Epitranscriptomic Microarray (8 × 60 K, Arraystar).

    Article Title: METTL16 promotes corneal nerve regeneration in diabetic corneal neuropathy.
    Article Snippet: As a leading ocular disorder caused by diabetes mellitus, diabetic corneal neuropathy (DCN) is characterized by decreased corneal sensation, ocular irritation, delayed corneal wound healing and corneal neuropathic pain.. Several researchers including us previously evidenced that DCN is regulated by several transcriptional and/or epigenetic factors.. However, the role of N6-methyladenosine (m6A) modification, the most common internal modification in eukaryotic RNAs, in the pathogenesis of DCN remains largely unexplored.

    Labeling:

    Article Title: Microarray analysis of tRNA-derived small RNA (tsRNA) in LPS-challenged macrophages treated with metformin.
    Article Snippet: Metformin, a widely used anti-diabetic drug, has demonstrated its efficacy in addressing various inflammatory conditions. tRNA-derived small RNA (tsRNA), a novel type of small non-coding RNA, exhibits diverse regulatory functions and holds promise as both a diagnostic biomarker and a therapeutic target for various diseases.. The purpose of this study is to investigate whether the abundance of tsRNAs changed in LPS versus LPS + metformintreated cells, utilizing microarray technology.. Firstly, we established an in vitro lipopolysaccharide (LPS)induced inflammation model using RAW264.7 macrophages and assessed the protective effects of metformin against inflammatory damage.

    Microarray:

    Article Title: Microarray analysis of tRNA-derived small RNA (tsRNA) in LPS-challenged macrophages treated with metformin.
    Article Snippet: Metformin, a widely used anti-diabetic drug, has demonstrated its efficacy in addressing various inflammatory conditions. tRNA-derived small RNA (tsRNA), a novel type of small non-coding RNA, exhibits diverse regulatory functions and holds promise as both a diagnostic biomarker and a therapeutic target for various diseases.. The purpose of this study is to investigate whether the abundance of tsRNAs changed in LPS versus LPS + metformintreated cells, utilizing microarray technology.. Firstly, we established an in vitro lipopolysaccharide (LPS)induced inflammation model using RAW264.7 macrophages and assessed the protective effects of metformin against inflammatory damage.

    Article Title: METTL3-mediated pre-miR-665/DLX3 m 6 A methylation facilitates the committed differentiation of stem cells from apical papilla
    Article Snippet: An Arraystar Super RNA Labeling Kit was used to designate these RNAs as cRNAs on their own. .. The cRNAs were combined and hybridized onto the Arraystar Mouse Epitranscriptomic Microarray (8 × 60 K, Arraystar). .. An Agilent G2505C scanner was used to scan the arrays in two-color channels after washing the slides.

    Article Title: The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4.
    Article Snippet: The “IP” and “Sup” RNAs were labeled with Cy5 and Cy3 respectively as cRNAs in separate reactions using Arraystar RNA Labeling protocol. .. The cRNAs were combined and hybridized onto Arraystar Mouse mRNA Epitranscriptomic Microarray (8 × 60 K, Arraystar). .. After washing the slides, the arrays were scanned in two-color channels by an Agilent Scanner G2505C.

    Article Title: The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9‐Mediated Splicing of NFATc4
    Article Snippet: The “IP” and “Sup” RNAs were labeled with Cy5 and Cy3 respectively as cRNAs in separate reactions using Arraystar RNA Labeling protocol. .. The cRNAs were combined and hybridized onto Arraystar Mouse mRNA Epitranscriptomic Microarray (8 × 60 K, Arraystar). .. After washing the slides, the arrays were scanned in two‐color channels by an Agilent Scanner G2505C.



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    Volcano plots showing the mature miRNAs differentially expressed in the TraxE126A mutants compared to wildtype littermates as identified by (A) miRNA sequencing and (B) miRNA <t>microarray.</t> Volcano plots showing the differentially expressed <t>small</t> <t>RNA</t> species identified using microarray analysis including (C) Precursor miRNAs (pre-miRNAs), (D) Small nucleolar RNAs (snoRNAs), (E) mature tRNAs and (F) tRNA-derived <t>small</t> <t>RNAs</t> (tsRNAs). In all the plots, the upregulated and downregulated miRNAs (false discovery rate, FDR <0.050 and log 2 fold change ≥0.200) are highlighted in red and blue, respectively. (TraxE126A, n=4; WT, n=5, all males). Largest changes were seen in tsRNA levels (majority are 5’-fragments) and mature miRNAs.
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    Volcano plots showing the mature miRNAs differentially expressed in the TraxE126A mutants compared to wildtype littermates as identified by (A) miRNA sequencing and (B) miRNA <t>microarray.</t> Volcano plots showing the differentially expressed <t>small</t> <t>RNA</t> species identified using microarray analysis including (C) Precursor miRNAs (pre-miRNAs), (D) Small nucleolar RNAs (snoRNAs), (E) mature tRNAs and (F) tRNA-derived <t>small</t> <t>RNAs</t> (tsRNAs). In all the plots, the upregulated and downregulated miRNAs (false discovery rate, FDR <0.050 and log 2 fold change ≥0.200) are highlighted in red and blue, respectively. (TraxE126A, n=4; WT, n=5, all males). Largest changes were seen in tsRNA levels (majority are 5’-fragments) and mature miRNAs.
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    Image Search Results


    Volcano plots showing the mature miRNAs differentially expressed in the TraxE126A mutants compared to wildtype littermates as identified by (A) miRNA sequencing and (B) miRNA microarray. Volcano plots showing the differentially expressed small RNA species identified using microarray analysis including (C) Precursor miRNAs (pre-miRNAs), (D) Small nucleolar RNAs (snoRNAs), (E) mature tRNAs and (F) tRNA-derived small RNAs (tsRNAs). In all the plots, the upregulated and downregulated miRNAs (false discovery rate, FDR <0.050 and log 2 fold change ≥0.200) are highlighted in red and blue, respectively. (TraxE126A, n=4; WT, n=5, all males). Largest changes were seen in tsRNA levels (majority are 5’-fragments) and mature miRNAs.

    Journal: bioRxiv

    Article Title: Genetic inactivation of the Translin/Trax RNase activity alters small RNAs including miRNAs, disrupts gene expression and impairs distinct forms of hippocampal synaptic plasticity and memory

    doi: 10.1101/2025.07.10.663777

    Figure Lengend Snippet: Volcano plots showing the mature miRNAs differentially expressed in the TraxE126A mutants compared to wildtype littermates as identified by (A) miRNA sequencing and (B) miRNA microarray. Volcano plots showing the differentially expressed small RNA species identified using microarray analysis including (C) Precursor miRNAs (pre-miRNAs), (D) Small nucleolar RNAs (snoRNAs), (E) mature tRNAs and (F) tRNA-derived small RNAs (tsRNAs). In all the plots, the upregulated and downregulated miRNAs (false discovery rate, FDR <0.050 and log 2 fold change ≥0.200) are highlighted in red and blue, respectively. (TraxE126A, n=4; WT, n=5, all males). Largest changes were seen in tsRNA levels (majority are 5’-fragments) and mature miRNAs.

    Article Snippet: The labeled RNA species are then hybridized onto Arraystar Small RNA Expression Microarray (8×15K format), scanned by an Agilent G2505C scanner followed by data processing and analysis.

    Techniques: Sequencing, Microarray, Derivative Assay

    (A) Venn diagram showing the overlap between mature miRNAs identified using miRNA sequencing and microarray analysis (with FDR<0.050 and log 2 fold change ≥0.200). A total of 12 miRNAs (10 upregulated and 2 downregulated) were found to be common and were used for target prediction using miRDB database. (B) An upset plot showing the shared and unique predicted mRNA target profiles in the miRDB database for the 12 common miRNAs. Only targets with miRDB Target Score ≥60 are included. (C) Top 15 KEGG pathways and (D) Gene Ontology (GO) Biological Process terms from the functional enrichment analysis of the predicted targets of the 12 common miRNAs performed using DAVID database.

    Journal: bioRxiv

    Article Title: Genetic inactivation of the Translin/Trax RNase activity alters small RNAs including miRNAs, disrupts gene expression and impairs distinct forms of hippocampal synaptic plasticity and memory

    doi: 10.1101/2025.07.10.663777

    Figure Lengend Snippet: (A) Venn diagram showing the overlap between mature miRNAs identified using miRNA sequencing and microarray analysis (with FDR<0.050 and log 2 fold change ≥0.200). A total of 12 miRNAs (10 upregulated and 2 downregulated) were found to be common and were used for target prediction using miRDB database. (B) An upset plot showing the shared and unique predicted mRNA target profiles in the miRDB database for the 12 common miRNAs. Only targets with miRDB Target Score ≥60 are included. (C) Top 15 KEGG pathways and (D) Gene Ontology (GO) Biological Process terms from the functional enrichment analysis of the predicted targets of the 12 common miRNAs performed using DAVID database.

    Article Snippet: The labeled RNA species are then hybridized onto Arraystar Small RNA Expression Microarray (8×15K format), scanned by an Agilent G2505C scanner followed by data processing and analysis.

    Techniques: Sequencing, Microarray, Functional Assay