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Novartis human il 2 rhil 2
Human Il 2 Rhil 2, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rhil+2/2+human+il/pm42132875-357-75-79
Average 86 stars, based on 1 article reviews
human il 2 rhil 2 - by Bioz Stars, 2026-11
86/100 stars

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Recombinant:

Article Title: A Literature Review of Interleukins in the Development and Treatment of Breast Cancer.
Article Snippet: .. Human recombinant IL-2 (Proleukin®, Novartis, Basel, Switzerland) received approval from the U.S. Food and Drug Administration (FDA) for the treatment of metastatic renal cell carcinoma in 1992 and metastatic melanoma in 1998. .. Human recombinant IL-2 (Proleukin, Novartis, Basel, Switzerland) received approval from the U.S. Food and Drug Administration (FDA) for the treatment of metastatic renal cell carcinoma in 1992 and metastatic melanoma in 1998.

Article Title: Monomethyl-auristatin E-based anti-CD137 (4-1BB) antibody drug conjugates are not suitable tools to deplete activated T lymphocytes
Article Snippet: Cells were cultured in IMDM supplemented with GlutaMAX (Gibco), 10% heat-inactivated fetal bovine serum, 1% penicillin/streptomycin, and 50 μM 2-mercaptoethanol (Gibco). .. Recombinant IL-2 (10 U/mL; Proleukin, Novartis) was added from day 3 onward. ..

Article Title: Compositions and methods of NKG2D chimeric antigen receptor T cells for controlling triple-negative breast cancer
Article Snippet: .. Human recombinant interleukin-2 (IL-2; Novartis) was added every 2-3 days to a 50 IU/mL final concentration and a cell density of 0.5×106 to 1×106 cells/ml was maintained. ..

Article Title: Optimized Multiple Amplification Protocol for the Production of Allogeneic Human Vγ9Vδ2 T Lymphocytes for Adoptive Cell Transfer Immunotherapy
Article Snippet: .. For the specific expansion of human Vγ9Vδ2 T lymphocytes, PBMCs were incubated with 3 μM bromohydrin pyrophosphate (BrHPP; Innate Pharma, Marseille, France) or 5 μM zoledronic acid (Sigma Aldrich, Saint-Louis, MI, USA) in RPMI medium supplemented with 10% heat-inactivated FBS, 2 mM L-glutamine, 10 mg/mL streptomycin, 100 IU/mL penicillin (all from Gibco, Thermo Fisher, Waltham, MA, USA), and 100 IU/mL human recombinant IL-2 (Proleukin, Novartis, Basel, Switzerland). ..

Article Title: A Literature Review of Interleukins in the Development and Treatment of Breast Cancer
Article Snippet: .. Human recombinant IL-2 (Proleukin ® , Novartis, Basel, Switzerland) received approval from the U.S. Food and Drug Administration (FDA) for the treatment of metastatic renal cell carcinoma in 1992 and metastatic melanoma in 1998. ..

Article Title: Droplet microfluidic profiling of NK cell cytotoxicity with machine learning-enabled target-cell death analysis.
Article Snippet: .. Isolated NK cells were cultured in RPMI-1640 (ATCC 30-2001TM) with 10% FBS (ATCC 30-2000TM), 1% penicillin– streptomycin (Sigma-Aldrich), 0.1% PlasmocinTM (InvivoGen), and 50 ng mL−1 recombinant human IL-2 (Proleukin®, Novartis/Clinigen). ..

Article Title: Optimized Multiple Amplification Protocol for the Production of Allogeneic Human Vγ9Vδ2 T Lymphocytes for Adoptive Cell Transfer Immunotherapy
Article Snippet: .. These pure human Vγ9Vδ2 T lymphocytes were then non-specifically expanded using mixed feeder cells composed of 35 Gy-irradiated Epstein-Barr Virus-transformed human B lymphocytes and PBMCs (each from 3 different donors) and PHA-L (Sigma) in RPMI medium supplemented with 10% heat-inactivated fetal calf serum, 2 mM L-glutamine, 10 mg/mL streptomycin, 100 IU/mL penicillin (all from Gibco), and 300 IU/mL recombinant human IL-2 (Novartis). ..

Article Title: Droplet microfluidic profiling of NK cell cytotoxicity with machine learning-enabled target-cell death analysis.
Article Snippet: .. For exNK cells, pbNK cells were expanded by co-culture for 3 weeks with irradiated (100 Gy) K562-mbIL-21 feeder cells (Clone 9, gift from Dr. Dean A. Lee's lab), replenished weekly (days 0, 7, 14) at a 1 : 2 NK : feeder ratio, maintaining NK density at 5 × 105 cells per mL post-replenishment, with media changes every 2–3 days (max 72 h) in NK culture medium (as described above) containing 50 ng mL−1 recombinant human IL-2 (rhIL-2) (Proleukin®, Novartis/Clinigen), at 37 °C and 5% CO2 in T25/T75 flasks. exNK-asc cells were obtained by culturing exNK in patient ascites for an additional 3 days. .. All blood draws, NK cell isolation, culturing, and preparation were performed by the Ashkar Lab (McMaster University, Hamilton, ON, Canada).

Food & Beverages:

Article Title: A Literature Review of Interleukins in the Development and Treatment of Breast Cancer.
Article Snippet: .. Human recombinant IL-2 (Proleukin®, Novartis, Basel, Switzerland) received approval from the U.S. Food and Drug Administration (FDA) for the treatment of metastatic renal cell carcinoma in 1992 and metastatic melanoma in 1998. .. Human recombinant IL-2 (Proleukin, Novartis, Basel, Switzerland) received approval from the U.S. Food and Drug Administration (FDA) for the treatment of metastatic renal cell carcinoma in 1992 and metastatic melanoma in 1998.

Article Title: A Literature Review of Interleukins in the Development and Treatment of Breast Cancer
Article Snippet: .. Human recombinant IL-2 (Proleukin ® , Novartis, Basel, Switzerland) received approval from the U.S. Food and Drug Administration (FDA) for the treatment of metastatic renal cell carcinoma in 1992 and metastatic melanoma in 1998. ..

Concentration Assay:

Article Title: Compositions and methods of NKG2D chimeric antigen receptor T cells for controlling triple-negative breast cancer
Article Snippet: .. Human recombinant interleukin-2 (IL-2; Novartis) was added every 2-3 days to a 50 IU/mL final concentration and a cell density of 0.5×106 to 1×106 cells/ml was maintained. ..

Incubation:

Article Title: Optimized Multiple Amplification Protocol for the Production of Allogeneic Human Vγ9Vδ2 T Lymphocytes for Adoptive Cell Transfer Immunotherapy
Article Snippet: .. For the specific expansion of human Vγ9Vδ2 T lymphocytes, PBMCs were incubated with 3 μM bromohydrin pyrophosphate (BrHPP; Innate Pharma, Marseille, France) or 5 μM zoledronic acid (Sigma Aldrich, Saint-Louis, MI, USA) in RPMI medium supplemented with 10% heat-inactivated FBS, 2 mM L-glutamine, 10 mg/mL streptomycin, 100 IU/mL penicillin (all from Gibco, Thermo Fisher, Waltham, MA, USA), and 100 IU/mL human recombinant IL-2 (Proleukin, Novartis, Basel, Switzerland). ..

Isolation:

Article Title: Droplet microfluidic profiling of NK cell cytotoxicity with machine learning-enabled target-cell death analysis.
Article Snippet: .. Isolated NK cells were cultured in RPMI-1640 (ATCC 30-2001TM) with 10% FBS (ATCC 30-2000TM), 1% penicillin– streptomycin (Sigma-Aldrich), 0.1% PlasmocinTM (InvivoGen), and 50 ng mL−1 recombinant human IL-2 (Proleukin®, Novartis/Clinigen). ..

Cell Culture:

Article Title: Droplet microfluidic profiling of NK cell cytotoxicity with machine learning-enabled target-cell death analysis.
Article Snippet: .. Isolated NK cells were cultured in RPMI-1640 (ATCC 30-2001TM) with 10% FBS (ATCC 30-2000TM), 1% penicillin– streptomycin (Sigma-Aldrich), 0.1% PlasmocinTM (InvivoGen), and 50 ng mL−1 recombinant human IL-2 (Proleukin®, Novartis/Clinigen). ..

Virus:

Article Title: Optimized Multiple Amplification Protocol for the Production of Allogeneic Human Vγ9Vδ2 T Lymphocytes for Adoptive Cell Transfer Immunotherapy
Article Snippet: .. These pure human Vγ9Vδ2 T lymphocytes were then non-specifically expanded using mixed feeder cells composed of 35 Gy-irradiated Epstein-Barr Virus-transformed human B lymphocytes and PBMCs (each from 3 different donors) and PHA-L (Sigma) in RPMI medium supplemented with 10% heat-inactivated fetal calf serum, 2 mM L-glutamine, 10 mg/mL streptomycin, 100 IU/mL penicillin (all from Gibco), and 300 IU/mL recombinant human IL-2 (Novartis). ..

Irradiation:

Article Title: Droplet microfluidic profiling of NK cell cytotoxicity with machine learning-enabled target-cell death analysis.
Article Snippet: .. For exNK cells, pbNK cells were expanded by co-culture for 3 weeks with irradiated (100 Gy) K562-mbIL-21 feeder cells (Clone 9, gift from Dr. Dean A. Lee's lab), replenished weekly (days 0, 7, 14) at a 1 : 2 NK : feeder ratio, maintaining NK density at 5 × 105 cells per mL post-replenishment, with media changes every 2–3 days (max 72 h) in NK culture medium (as described above) containing 50 ng mL−1 recombinant human IL-2 (rhIL-2) (Proleukin®, Novartis/Clinigen), at 37 °C and 5% CO2 in T25/T75 flasks. exNK-asc cells were obtained by culturing exNK in patient ascites for an additional 3 days. .. All blood draws, NK cell isolation, culturing, and preparation were performed by the Ashkar Lab (McMaster University, Hamilton, ON, Canada).



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