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Krajete GmbH ion-pair reversed-phase hplc
Ion Pair Reversed Phase Hplc, supplied by Krajete GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/reverse+phase+hplc/capillary+ion+pair+reversed+phase+hplc/pm12497635-93-25-34
Average 90 stars, based on 1 article reviews
ion-pair reversed-phase hplc - by Bioz Stars, 2026-09
90/100 stars

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High Performance Liquid Chromatography:

Article Title: The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides.
Article Snippet: As interest in oligonucleotide (ON) therapeutics is increasing, there is a need to develop suitable analytical methods able to properly analyze those molecules.. However, an issue exists in the adsorption of ONs on different parts of the instrumentation during their analysis.. The goal of the present paper was to comprehensively evaluate various types of bioinert materials used in ion-pairing reversed-phase (IPRPLC) and hydrophilic interaction chromatography (HILIC) to mitigate this issue for 15to 100-mer DNA and RNA oligonucleotides.

Article Title: Nanostructured porous polymer monolithic columns for capillary liquid chromatography of peptides.
Article Snippet: .. Huber, A. Krajete, Analysis of nucleic acids by capillary ion-pair reversed-phase HPLC coupled to negative-ion electrospray ionization mass spectrometry, Anal. ..

other:

Article Title: Characterization of therapeutic oligonucleotides by liquid chromatography.
Article Snippet: Marketed therapies in the pharmaceutical landscape are rapidly evolving and getting more diverse.. Small molecule medicines have dominated in the past while antibodies have grown dramatically in recent years.. However, the failure of traditional small and large molecules in accessing certain targets has led to increased R&D efforts to develop alternative modalities.

Article Title: Effect of ion-pairing reagent hydrophobicity on liquid chromatography and mass spectrometry analysis of oligonucleotides.
Article Snippet: Huber , A. Krajete , Analysis of nucleic acids by capillary ion-pair re- versed-phase HPLC coupled to negative-ion electrospray ionization mass spectrometry, Anal.

Article Title: Effect of ion-pairing reagent hydrophobicity on liquid chromatography and mass spectrometry analysis of oligonucleotides.
Article Snippet: 44] H.M. Huang , A. Krajete , Analysis of nucleic acids by capillary ion-pair reversed-phaseHPLC coupled to negative-ion electrospray ionization mass spec- trometry, Anal.

Article Title: THERAPEUTIC OLIGONUCLEOTIDES, IMPURITIES, DEGRADANTS, AND THEIR CHARACTERIZATION BY MASS SPECTROMETRY.
Article Snippet: Oligonucleotides are an emerging class of drugs that are manufactured by solid‐phase synthesis.. As a chemical class, they have unique product‐related impurities and degradants, characterization of which is an essential step in drug development.. The synthesis cycle, impurities produced during the synthesis and degradation products are presented and discussed.

Mass Spectrometry:

Article Title: Nanostructured porous polymer monolithic columns for capillary liquid chromatography of peptides.
Article Snippet: .. Huber, A. Krajete, Analysis of nucleic acids by capillary ion-pair reversed-phase HPLC coupled to negative-ion electrospray ionization mass spectrometry, Anal. ..



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Light‐triggered chemical fuel generation from photolytic fuel‐carrier molecules. (a) Design and photolytic mechanism of fuel‐carrier molecules, ONB‐HFIP, which undergo UV‐triggered photolysis to release HFIP fuel and reaction byproducts. (b) Color change of ONB‐HFIP in solution as a function of UV irradiation time. (c) Time‐resolved HPLC chromatograms and (d) UV‐vis absorption spectra of ONB‐HFIP in solution as a function of UV irradiation time. (e) Conversion degree of photolytic reaction, estimated from the changing ratio of HPLC peak areas and UV‐vis absorption intensities at 343 and 264 nm over time.

Journal: Advanced Materials (Deerfield Beach, Fla.)

Article Title: Photochemical Fuel Carrier Molecules for Robotic Embodied Energy

doi: 10.1002/adma.202520447

Figure Lengend Snippet: Light‐triggered chemical fuel generation from photolytic fuel‐carrier molecules. (a) Design and photolytic mechanism of fuel‐carrier molecules, ONB‐HFIP, which undergo UV‐triggered photolysis to release HFIP fuel and reaction byproducts. (b) Color change of ONB‐HFIP in solution as a function of UV irradiation time. (c) Time‐resolved HPLC chromatograms and (d) UV‐vis absorption spectra of ONB‐HFIP in solution as a function of UV irradiation time. (e) Conversion degree of photolytic reaction, estimated from the changing ratio of HPLC peak areas and UV‐vis absorption intensities at 343 and 264 nm over time.

Article Snippet: High‐performance liquid chromatography (HPLC) spectra were obtained using an analytical reversed‐phase HPLC (Hitachi 5000 series Chromaster).

Techniques: Irradiation