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National Reference Center for Legionella oligonucleotides for hadv species genotyping by fmca
Age distribution of <t>HAdV-positive</t> (dark gray) and HAdV-negative (light gray) patients within the digital/virologic surveillance cohort Age groups: Neonates: 0–28 days, infants: 29 days–12 months, toddlers: 13–24 months, pre-school children: 3–5 years, schoolchildren/adolescents: 6–18 years.
Oligonucleotides For Hadv Species Genotyping By Fmca, supplied by National Reference Center for Legionella, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
oligonucleotides for hadv species genotyping by fmca - by Bioz Stars, 2026-11
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1) Product Images from "Linking digital surveillance and in-depth virology to study clinical patterns of viral respiratory infections in vulnerable patient populations"

Article Title: Linking digital surveillance and in-depth virology to study clinical patterns of viral respiratory infections in vulnerable patient populations

Journal: iScience

doi: 10.1016/j.isci.2022.104276

Age distribution of HAdV-positive (dark gray) and HAdV-negative (light gray) patients within the digital/virologic surveillance cohort Age groups: Neonates: 0–28 days, infants: 29 days–12 months, toddlers: 13–24 months, pre-school children: 3–5 years, schoolchildren/adolescents: 6–18 years.
Figure Legend Snippet: Age distribution of HAdV-positive (dark gray) and HAdV-negative (light gray) patients within the digital/virologic surveillance cohort Age groups: Neonates: 0–28 days, infants: 29 days–12 months, toddlers: 13–24 months, pre-school children: 3–5 years, schoolchildren/adolescents: 6–18 years.

Techniques Used:

Baseline patient characteristics
Figure Legend Snippet: Baseline patient characteristics

Techniques Used:

Descriptive list of co-infections (N = 322)
Figure Legend Snippet: Descriptive list of co-infections (N = 322)

Techniques Used:

Scatterplot of ViVI Scores measured in HAdV-positive patients (N = 571) ViVI Score values may range from 0–48, reflecting increasing disease severity with increasing ViVI Scores. The vertical bold black line marks the cohort average ViVI Score of 14.5, i.e. the 50 th percentile in the overall cohort. Dark gray dots indicate cases with above-average ViVI Scores and light gray dots indicate cases with below-average ViVI Scores. Numbers (n) indicate the number of cases below the cohort average ViVI Score and above the cohort average, respectively.
Figure Legend Snippet: Scatterplot of ViVI Scores measured in HAdV-positive patients (N = 571) ViVI Score values may range from 0–48, reflecting increasing disease severity with increasing ViVI Scores. The vertical bold black line marks the cohort average ViVI Score of 14.5, i.e. the 50 th percentile in the overall cohort. Dark gray dots indicate cases with above-average ViVI Scores and light gray dots indicate cases with below-average ViVI Scores. Numbers (n) indicate the number of cases below the cohort average ViVI Score and above the cohort average, respectively.

Techniques Used:

ViVI Score dynamics illustrating disease progression in the HAdV-D80 index case Initial X-ray on hospital day 4 (I) showed diffuse patchy lung infiltrates, corresponding to respiratory distress syndrome grade I. Follow-up imaging on hospital day 10 (II) showed homogenic lung opacity due to diffuse bilateral atelectasis (“white lungs”), corresponding to respiratory distress syndrome grade IV. Follow-up imaging on hospital day 14 (III) revealed generalized compartment syndrome with ongoing abdominal swelling, pleural, and pericardial effusion. (B) Adenovirus load kinetics in different body compartments over time: Cq values (inverted vertical axis) during PCR-testing were used to estimate virus load. Abbreviations: ViVI – Vienna Vaccine Safety Initiative, Cq-Quantitation Cycle.
Figure Legend Snippet: ViVI Score dynamics illustrating disease progression in the HAdV-D80 index case Initial X-ray on hospital day 4 (I) showed diffuse patchy lung infiltrates, corresponding to respiratory distress syndrome grade I. Follow-up imaging on hospital day 10 (II) showed homogenic lung opacity due to diffuse bilateral atelectasis (“white lungs”), corresponding to respiratory distress syndrome grade IV. Follow-up imaging on hospital day 14 (III) revealed generalized compartment syndrome with ongoing abdominal swelling, pleural, and pericardial effusion. (B) Adenovirus load kinetics in different body compartments over time: Cq values (inverted vertical axis) during PCR-testing were used to estimate virus load. Abbreviations: ViVI – Vienna Vaccine Safety Initiative, Cq-Quantitation Cycle.

Techniques Used: Biomarker Discovery, Imaging, Virus, Quantitation Assay

Relative variable importance analysis for top-5 clinical features of HAdV-positive patients (n = 571) using the permutation feature importance measure The relative feature importance of the most important feature is set to 100. The values of the other features are scaled accordingly relative to the most important feature. Level of importance of top-5 features is reflected as follows: white indicates importance <33, gray indicates importance ≥33 and <66, black indicates importance ≥66.
Figure Legend Snippet: Relative variable importance analysis for top-5 clinical features of HAdV-positive patients (n = 571) using the permutation feature importance measure The relative feature importance of the most important feature is set to 100. The values of the other features are scaled accordingly relative to the most important feature. Level of importance of top-5 features is reflected as follows: white indicates importance <33, gray indicates importance ≥33 and <66, black indicates importance ≥66.

Techniques Used:

HAdV-D80 phylogenetic clustering (whole genome, E4, E3) Phylogenetic clustering of the HAdV-D80 (A) whole genome, (B) early gene region 4 (E4), and (C) early gene region 3 (E3) sequence with all other HAdV-D prototype sequences. Bootstrap values > 80% were considered robust. Arrow indicates the clustering position of HAdV-D80.
Figure Legend Snippet: HAdV-D80 phylogenetic clustering (whole genome, E4, E3) Phylogenetic clustering of the HAdV-D80 (A) whole genome, (B) early gene region 4 (E4), and (C) early gene region 3 (E3) sequence with all other HAdV-D prototype sequences. Bootstrap values > 80% were considered robust. Arrow indicates the clustering position of HAdV-D80.

Techniques Used: Sequencing

HAdV-D80 phylogenetic clustering (hexon, fiber, penton) Phylogenetic clustering of the HAdV-D80 (A) hexon gene, (B) fiber gene, and (C) penton base gene sequence with all other HAdV-D prototype sequences. Bootstrap values > 80% were considered robust. Arrow indicates the clustering position of HAdV-D80.
Figure Legend Snippet: HAdV-D80 phylogenetic clustering (hexon, fiber, penton) Phylogenetic clustering of the HAdV-D80 (A) hexon gene, (B) fiber gene, and (C) penton base gene sequence with all other HAdV-D prototype sequences. Bootstrap values > 80% were considered robust. Arrow indicates the clustering position of HAdV-D80.

Techniques Used: Sequencing


Figure Legend Snippet:

Techniques Used: Virus, Recombinant, DNA Library Preparation, Software, Clinical Proteomics

Related Articles

Polymerase Chain Reaction:

Article Title: Linking digital surveillance and in-depth virology to study clinical patterns of viral respiratory infections in vulnerable patient populations
Article Snippet: Oligonucleotides for hAdV species A-F detection , National Reference Center for Influenza , Barbara Chmielewicz, Andreas Nitsche, Brunhilde Schweiger, Heinz Ellerbrok, Development of a PCR-Based Assay for Detection, Quantification, and Genotyping of Human Adenoviruses, Clinical Chemistry, Volume 51, Issue 8, 1 August 2005, Pages 1365–1373, https://doi.org/10.1373/clinchem.2004.045088 , https://academic.oup.com/clinchem/article/51/8/1365/5629946. .. Oligonucleotides for hAdV species genotyping by FMCA , National Reference Center for Influenza , Barbara Chmielewicz, Andreas Nitsche, Brunhilde Schweiger, Heinz Ellerbrok, Development of a PCR-Based Assay for Detection, Quantification, and Genotyping of Human Adenoviruses, Clinical Chemistry, Volume 51, Issue 8, 1 August 2005, Pages 1365–1373, https://doi.org/10.1373/clinchem.2004.045088 , https://academic.oup.com/clinchem/article/51/8/1365/5629946. ..



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