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Pyrosequencing Inc quantitative methylation assays
Ki-67 stratified by <t>methylation</t> status of ADIPOQ ( a ), GATA-4 ( b ), and YAP1 ( c ) in the tumor tissue. For the ADIPOQ gene ( a ), the “unmethylated” group was combined with the “partially methylated” group due to the presence of only one sample with an unmethylated status. For the YAP-1 gene ( c ), the “partially methylated” group was combined with the “methylated” group due to the presence of only two samples with methylated status. Data are shown as raw values with medians and IQR. Group differences were analyzed with Student’s t -test ( c ), Mann–Whitney U-test ( a ), and one-way ANOVA ( b ).
Quantitative Methylation Assays, supplied by Pyrosequencing Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/quantitative+pyrosequencing/pmc12609348-258-8-12?v=Pyrosequencing+Inc
Average 86 stars, based on 1 article reviews
quantitative methylation assays - by Bioz Stars, 2026-08
86/100 stars

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1) Product Images from "Molecular Implications of ADIPOQ, GAS5, GATA4 , and YAP1 Methylation in Triple-Negative Breast Cancer Prognosis"

Article Title: Molecular Implications of ADIPOQ, GAS5, GATA4 , and YAP1 Methylation in Triple-Negative Breast Cancer Prognosis

Journal: International Journal of Molecular Sciences

doi: 10.3390/ijms262110652

Ki-67 stratified by methylation status of ADIPOQ ( a ), GATA-4 ( b ), and YAP1 ( c ) in the tumor tissue. For the ADIPOQ gene ( a ), the “unmethylated” group was combined with the “partially methylated” group due to the presence of only one sample with an unmethylated status. For the YAP-1 gene ( c ), the “partially methylated” group was combined with the “methylated” group due to the presence of only two samples with methylated status. Data are shown as raw values with medians and IQR. Group differences were analyzed with Student’s t -test ( c ), Mann–Whitney U-test ( a ), and one-way ANOVA ( b ).
Figure Legend Snippet: Ki-67 stratified by methylation status of ADIPOQ ( a ), GATA-4 ( b ), and YAP1 ( c ) in the tumor tissue. For the ADIPOQ gene ( a ), the “unmethylated” group was combined with the “partially methylated” group due to the presence of only one sample with an unmethylated status. For the YAP-1 gene ( c ), the “partially methylated” group was combined with the “methylated” group due to the presence of only two samples with methylated status. Data are shown as raw values with medians and IQR. Group differences were analyzed with Student’s t -test ( c ), Mann–Whitney U-test ( a ), and one-way ANOVA ( b ).

Techniques Used: Methylation, MANN-WHITNEY

Age at diagnosis stratified by methylation status of ADIPOQ ( a ), GATA-4 ( b ), and YAP1 ( c ). For the ADIPOQ gene ( a ), the “unmethylated” group was combined with the “partially methylated” group due to the presence of only one sample with an unmethylated status. For the YAP-1 gene ( c ), the “partially methylated” group was combined with the “methylated” group due to the presence of only two samples with methylated status. Data are shown as raw values with medians and IQR. Group differences were analyzed with Student’s t -test ( a , c ) and Kruskal–Wallis test ( b ).
Figure Legend Snippet: Age at diagnosis stratified by methylation status of ADIPOQ ( a ), GATA-4 ( b ), and YAP1 ( c ). For the ADIPOQ gene ( a ), the “unmethylated” group was combined with the “partially methylated” group due to the presence of only one sample with an unmethylated status. For the YAP-1 gene ( c ), the “partially methylated” group was combined with the “methylated” group due to the presence of only two samples with methylated status. Data are shown as raw values with medians and IQR. Group differences were analyzed with Student’s t -test ( a , c ) and Kruskal–Wallis test ( b ).

Techniques Used: Biomarker Discovery, Methylation

ADIPOQ methylation as having the most significant associations, being associated with all five survival endpoints in TCGA TNBC cohort, including ( a ) DSS ( p = 0.023), ( b ) DFI ( p = 0.013), ( c ) PFI ( p = 0.037), ( d ) RFS ( p = 0.011) and ( e ) OS ( p = 0.028).
Figure Legend Snippet: ADIPOQ methylation as having the most significant associations, being associated with all five survival endpoints in TCGA TNBC cohort, including ( a ) DSS ( p = 0.023), ( b ) DFI ( p = 0.013), ( c ) PFI ( p = 0.037), ( d ) RFS ( p = 0.011) and ( e ) OS ( p = 0.028).

Techniques Used: Methylation



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