structural analysis program pymol (DeLano Scientific)
90
Structured Review
DeLano Scientific
structural analysis program pymol
Structural Analysis Program Pymol, supplied by DeLano Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/program+pymol/structural+analysis+program+pymol/pmc06755804-422-40-43
Average 90 stars, based on 1 article reviews
Structural Analysis Program Pymol, supplied by DeLano Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/program+pymol/structural+analysis+program+pymol/pmc06755804-422-40-43
Average 90 stars, based on 1 article reviews
structural analysis program pymol - by Bioz Stars,
2026-10
90/100 stars
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1) Product Images from "The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis"
Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis
Journal: The Journal of Biological Chemistry
doi: 10.1074/jbc.RA118.007265
Figure Legend Snippet: Identification of P152Lp53 mutation in a patient sample and prevalence of somatic P152Lp53 missense mutations in human cancers. a, immunohistochemistry for mutant p53 by PAb240 antibody (indicated by →) on an oral cancer sample; b, sequence chromatogram showing C > T substitution at 152 position; c, location of Pro-152 (shown in pink) in 3D structure of the p53 core domain bound to DNA visualized by PyMOL (molecular visualization software); d, multiple sequence alignment of human TP53 protein sequence across various organisms. The Pro-152 residue is indicated by a black arrow. e, prevalence of missense mutations in a stretch of 150–155 amino acids of p53 analyzed from COSMIC database version 86; f, bar plot representation of number and frequency of various missense mutations present at TP53 (Pro-152) loci out of 111 samples of available data at COSMIC. The percentage frequency of various amino acid substitutions are shown above the bars. g, bar plot representation of number and frequency distribution of P152Lp53 mutation occurrence over various cancer tissue types out of 111 samples of P152L mutations. CNS, central nervous system, others: adrenal gland, breast, hematopoietic and lymphoid tissue, liver, lung, pancreas, skin, soft tissue, and stomach tissue.
Techniques Used: Mutagenesis, Immunohistochemistry, Sequencing, Software, Residue
Related Articles
Mutagenesis:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Immunohistochemistry:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Sequencing:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Software:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Residue:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with |
