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Dotmatics Limited dotmatics software platform
Dotmatics Software Platform, supplied by Dotmatics Limited, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/platform+software/dotmatics+platform+software/us12600726-726-32-35
Average 86 stars, based on 1 article reviews
dotmatics software platform - by Bioz Stars, 2026-10
86/100 stars

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Related Articles

Concentration Assay:

Article Title: Antagonists of the muscarinic acetylcholine receptor M4
Article Snippet: .. Concentration-response curves were generated using a four-parameter logistical equation in XLFit curve fitting software (IDBS, Bridgewater, NJ) for Excel (Microsoft, Redmond, WA) or Prism (GraphPad Software, Inc., San Diego, CA) or the Dotmatics software platform (Dotmatics, Bishop's Stortford, UK). ..

Article Title: Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M 4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy.
Article Snippet: .. Potency (EC50) and maximum response (% ACh Max) for compounds was determined using a four-parameter logistical equation using GraphPad Prism (La Jolla, CA) or the Dotmatics software platform (Woburn, MA): y bottom top bottom 1 10 A(LogEC50 )Hillslope = + + where A is the molar concentration of the compound; bottom and top denote the lower and upper plateaus of the concentration−response curve; HillSlope is the Hill coefficient that describes the steepness of the curve; and EC50 is the molar concentration of compound required to generate a response halfway between the top and bottom. ..

Article Title: Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2.
Article Snippet: .. For concentration response curves, normalized data were fit to a four-parameter logistic equation using GraphPad Prism (La Jolla, California) or the Dotmatics software platform (Dotmatics, Bishop’s Stortford, UK). y bottom top bottom 1 10 EC A Hillslope(log 50 ) = + + https://doi.org/10.1021/acs.jmedchem.5c02796 J. Med. ..

Generated:

Article Title: Antagonists of the muscarinic acetylcholine receptor M4
Article Snippet: .. Concentration-response curves were generated using a four-parameter logistical equation in XLFit curve fitting software (IDBS, Bridgewater, NJ) for Excel (Microsoft, Redmond, WA) or Prism (GraphPad Software, Inc., San Diego, CA) or the Dotmatics software platform (Dotmatics, Bishop's Stortford, UK). ..

Software:

Article Title: Antagonists of the muscarinic acetylcholine receptor M4
Article Snippet: .. Concentration-response curves were generated using a four-parameter logistical equation in XLFit curve fitting software (IDBS, Bridgewater, NJ) for Excel (Microsoft, Redmond, WA) or Prism (GraphPad Software, Inc., San Diego, CA) or the Dotmatics software platform (Dotmatics, Bishop's Stortford, UK). ..

other:

Article Title: Antagonists of the muscarinic acetylcholine receptor M4
Article Snippet: cDNA, along with the chimeric G protein Gqi5, were transfected into Chinese hamster ovary (CHO-K1) cells purchased from the American Type Culture Collection using Lipofectamine2000.

Article Title: Positive modulators of the muscarinic acetylcholine receptor M4
Article Snippet: Immediately, 20 μL of the 2× dye solution (final 1.15 μM) was added to each well of the cell plate using a Multidrop Combi dispenser (Thermo Fisher, Waltham, MA).

Article Title: Positive modulators of the muscarinic acetylcholine receptor M4
Article Snippet: Immediately, 20 μL of the 2× dye solution (final 1.15 μM) was added to each well of the cell plate using a Multidrop Combi dispenser (Thermo Fisher, Waltham, MA).



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