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fosfomycin  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology fosfomycin
    Fig. 1. (a) Chemical structure of <t>fosfomycin</t> and (b) the internal standard: fosfomycin- 13C3. Only one of the enantiomers from the racemic mixture is depicted. The three 13C atoms are marked as C*.
    Fosfomycin, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/phosphonomycin/pm28759841-48-0-4?v=Santa+Cruz+Biotechnology
    Average 86 stars, based on 1 article reviews
    fosfomycin - by Bioz Stars, 2026-08
    86/100 stars

    Images

    1) Product Images from "A fast and sensitive LC-MS/MS method for the quantification of fosfomycin in human urine and plasma using one sample preparation method and HILIC chromatography."

    Article Title: A fast and sensitive LC-MS/MS method for the quantification of fosfomycin in human urine and plasma using one sample preparation method and HILIC chromatography.

    Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

    doi: 10.1016/j.jchromb.2017.07.036

    Fig. 1. (a) Chemical structure of fosfomycin and (b) the internal standard: fosfomycin- 13C3. Only one of the enantiomers from the racemic mixture is depicted. The three 13C atoms are marked as C*.
    Figure Legend Snippet: Fig. 1. (a) Chemical structure of fosfomycin and (b) the internal standard: fosfomycin- 13C3. Only one of the enantiomers from the racemic mixture is depicted. The three 13C atoms are marked as C*.

    Techniques Used:

    Fig. 2. Chromatograms of fosfomycin in urine (a) and plasma (b) and the internal standard in urine (c) and in plasma (d) after injection of calibration standard 3.
    Figure Legend Snippet: Fig. 2. Chromatograms of fosfomycin in urine (a) and plasma (b) and the internal standard in urine (c) and in plasma (d) after injection of calibration standard 3.

    Techniques Used: Clinical Proteomics, Injection



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    Image Search Results


    ( A ) Phase contrast images of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells, harvested in the exponential and stationary growth phase. Scale bar: 5 µm. ( B ) Superplots showing the distribution of cell lengths in populations of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells in the exponential (exp) and stationary (stat) growth phase. Data (n=100 cells per replicate) are presented as described for . The statistical significance ( p -value) of differences between conditions was assessed using a two-sided Welch’s t -test. ns indicates p -values >0.1. ( C ) Serial dilution spot assay investigating the growth of C. crescentus Δ anmK (PR252) and Δ amgK (PR262) on plates containing different concentrations of ampicillin. The cells were spotted on the same plates as those depicted in . See for all replicates (n=3 independent experiments). ( D ) Levels of N-acetylmuramic acid (Mur N Ac) in the cytoplasm of C. crescentus wild-type and Δ amgK (PR262) cells, measured by metabolomics analysis through quantification of the corresponding mass spectrometric peak areas. The mass spectrometric peak areas were normalized against the mean obtained for the Δ amgK mutant. The statistical significance of differences between the two strains was determined using a two-sided Welch’s t -test. ( E ) Analysis of the growth of C. crescentus wild-type, Δ nagK (PR255), and Δ amgK (PR262) cells on agar containing a fosfomycin gradient. The fosfomycin concentrations on the MIC test strip are indicated in the legend on the right.

    Journal: eLife

    Article Title: Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in Caulobacter crescentus

    doi: 10.7554/eLife.109465

    Figure Lengend Snippet: ( A ) Phase contrast images of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells, harvested in the exponential and stationary growth phase. Scale bar: 5 µm. ( B ) Superplots showing the distribution of cell lengths in populations of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells in the exponential (exp) and stationary (stat) growth phase. Data (n=100 cells per replicate) are presented as described for . The statistical significance ( p -value) of differences between conditions was assessed using a two-sided Welch’s t -test. ns indicates p -values >0.1. ( C ) Serial dilution spot assay investigating the growth of C. crescentus Δ anmK (PR252) and Δ amgK (PR262) on plates containing different concentrations of ampicillin. The cells were spotted on the same plates as those depicted in . See for all replicates (n=3 independent experiments). ( D ) Levels of N-acetylmuramic acid (Mur N Ac) in the cytoplasm of C. crescentus wild-type and Δ amgK (PR262) cells, measured by metabolomics analysis through quantification of the corresponding mass spectrometric peak areas. The mass spectrometric peak areas were normalized against the mean obtained for the Δ amgK mutant. The statistical significance of differences between the two strains was determined using a two-sided Welch’s t -test. ( E ) Analysis of the growth of C. crescentus wild-type, Δ nagK (PR255), and Δ amgK (PR262) cells on agar containing a fosfomycin gradient. The fosfomycin concentrations on the MIC test strip are indicated in the legend on the right.

    Article Snippet: Resistance against fosfomycin was assessed using Fosfomycin MIC Test Strips (Liofilchem, Italy).

    Techniques: Serial Dilution, Spot Test, Mutagenesis, Stripping Membranes

    ( A ) Phase contrast images of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells, harvested in the exponential and stationary growth phase. Scale bar: 5 µm. ( B ) Superplots showing the distribution of cell lengths in populations of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells in the exponential (exp) and stationary (stat) growth phase. Data (n=100 cells per replicate) are presented as described for . The statistical significance ( p -value) of differences between conditions was assessed using a two-sided Welch’s t -test. ns indicates p -values >0.1. ( C ) Serial dilution spot assay investigating the growth of C. crescentus Δ anmK (PR252) and Δ amgK (PR262) on plates containing different concentrations of ampicillin. The cells were spotted on the same plates as those depicted in . See for all replicates (n=3 independent experiments). ( D ) Levels of N-acetylmuramic acid (Mur N Ac) in the cytoplasm of C. crescentus wild-type and Δ amgK (PR262) cells, measured by metabolomics analysis through quantification of the corresponding mass spectrometric peak areas. The mass spectrometric peak areas were normalized against the mean obtained for the Δ amgK mutant. The statistical significance of differences between the two strains was determined using a two-sided Welch’s t -test. ( E ) Analysis of the growth of C. crescentus wild-type, Δ nagK (PR255), and Δ amgK (PR262) cells on agar containing a fosfomycin gradient. The fosfomycin concentrations on the MIC test strip are indicated in the legend on the right.

    Journal: eLife

    Article Title: Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in Caulobacter crescentus

    doi: 10.7554/eLife.109465

    Figure Lengend Snippet: ( A ) Phase contrast images of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells, harvested in the exponential and stationary growth phase. Scale bar: 5 µm. ( B ) Superplots showing the distribution of cell lengths in populations of C. crescentus wild-type, Δ anmK (PR252), and Δ amgK (PR262) cells in the exponential (exp) and stationary (stat) growth phase. Data (n=100 cells per replicate) are presented as described for . The statistical significance ( p -value) of differences between conditions was assessed using a two-sided Welch’s t -test. ns indicates p -values >0.1. ( C ) Serial dilution spot assay investigating the growth of C. crescentus Δ anmK (PR252) and Δ amgK (PR262) on plates containing different concentrations of ampicillin. The cells were spotted on the same plates as those depicted in . See for all replicates (n=3 independent experiments). ( D ) Levels of N-acetylmuramic acid (Mur N Ac) in the cytoplasm of C. crescentus wild-type and Δ amgK (PR262) cells, measured by metabolomics analysis through quantification of the corresponding mass spectrometric peak areas. The mass spectrometric peak areas were normalized against the mean obtained for the Δ amgK mutant. The statistical significance of differences between the two strains was determined using a two-sided Welch’s t -test. ( E ) Analysis of the growth of C. crescentus wild-type, Δ nagK (PR255), and Δ amgK (PR262) cells on agar containing a fosfomycin gradient. The fosfomycin concentrations on the MIC test strip are indicated in the legend on the right.

    Article Snippet: Chemical compound, drug , fosfomycin MIC test stripes , Liofilchem, Italy , Cat. #: 92078 , .

    Techniques: Serial Dilution, Spot Test, Mutagenesis, Stripping Membranes