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inverted phase contrast microscope  (Olympus)


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    Structured Review

    Olympus inverted phase contrast microscope
    Inverted Phase Contrast Microscope, supplied by Olympus, used in various techniques. Bioz Stars score: 99/100, based on 3773 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/phase-contrast+microscope/CKX53+Cell+Culture+Microscope/pm41933720-52-8-13
    Average 99 stars, based on 3773 article reviews
    inverted phase contrast microscope - by Bioz Stars, 2026-09
    99/100 stars

    Images

    Related Articles

    Microscopy:

    Article Title: Silencing of SIVA-1 promotes cisplatin resistance in gastric cancer via the Bcl-2/BAX-mediated mitochondria-dependent apoptosis pathway
    Article Snippet: .. Colony formation was manually counted under an inverted optical microscope (CKX53; Olympus Corporation) at ×40 magnification. ..

    Article Title: Silencing of SIVA-1 promotes cisplatin resistance in gastric cancer via the Bcl-2/BAX-mediated mitochondria-dependent apoptosis pathway
    Article Snippet: .. The healing process was observed under ×40 magnification using an inverted optical microscope (CKX53; Olympus Corporation) at 0, 24 and 48 h, respectively. .. The area of the scratches was measured using the microscope companion software (Confluency Checker Software; version 1.2; Olympus Corporation).

    Article Title: PPARα-CD36-CAV1-mediated docosahexaenoic acid (DHA) uptake promotes muscle fiber development in grass carp ( Ctenopharyngodon idellus )
    Article Snippet: .. Finally, the myoblasts were observed and imaged using an inverted fluorescence microscope (Model CKX53, Olympus Corporation, Tokyo, Japan), and the total number of nuclei as well as the number of EdU-positive nuclei were quantified using ImageJ software (version 1.54p, National Institutes of Health, Bethesda, MD, USA). ..

    Article Title: Caffeic acid phenethyl ester ameliorates high-fat diet-induced muscle textural deterioration in grass carp ( Ctenopharyngodon idellus ) by modulating adipose-muscle crosstalk via myostatin-taz signaling
    Article Snippet: .. Samples were mounted and observed/imaged using an inverted fluorescence microscope (Model CKX53, Olympus, Tokyo, Japan). .. Bodipy (505/515, Thermo Fisher Scientific, Waltham, MA, USA) was dissolved in dimethylsulfoxide (DMSO) to prepare a 5 mmol/L stock solution (aliquoted and stored at 4 °C).

    Fluorescence:

    Article Title: Immunomodulatory effects of biodegradable Mg–Cu–Zn alloy in esophageal cancer
    Article Snippet: After treatment, cells were rinsed twice with PBS and stained using a Calcein/PI Cell Viability/Cytotoxicity Assay Kit (Beyotime, China) for 30 min in the dark. .. Fluorescence images were captured to assess cell morphology and viability (CKX53, Olympus, Japan). ..

    Article Title: PPARα-CD36-CAV1-mediated docosahexaenoic acid (DHA) uptake promotes muscle fiber development in grass carp ( Ctenopharyngodon idellus )
    Article Snippet: .. Finally, the myoblasts were observed and imaged using an inverted fluorescence microscope (Model CKX53, Olympus Corporation, Tokyo, Japan), and the total number of nuclei as well as the number of EdU-positive nuclei were quantified using ImageJ software (version 1.54p, National Institutes of Health, Bethesda, MD, USA). ..

    Article Title: Caffeic acid phenethyl ester ameliorates high-fat diet-induced muscle textural deterioration in grass carp ( Ctenopharyngodon idellus ) by modulating adipose-muscle crosstalk via myostatin-taz signaling
    Article Snippet: .. Samples were mounted and observed/imaged using an inverted fluorescence microscope (Model CKX53, Olympus, Tokyo, Japan). .. Bodipy (505/515, Thermo Fisher Scientific, Waltham, MA, USA) was dissolved in dimethylsulfoxide (DMSO) to prepare a 5 mmol/L stock solution (aliquoted and stored at 4 °C).

    other:

    Article Title: Immunomodulatory effects of biodegradable Mg–Cu–Zn alloy in esophageal cancer
    Article Snippet: The cells were washed twice with PBS and then observed and imaged under a fluorescence microscope (CKX53, Olympus, Japan).

    Article Title: Immunomodulatory effects of biodegradable Mg–Cu–Zn alloy in esophageal cancer
    Article Snippet: Images from ten random fields were captured using a fluorescence microscope (CKX53, Olympus, Japan) and analyzed using ImageJ software.

    Article Title: Immunomodulatory effects of biodegradable Mg–Cu–Zn alloy in esophageal cancer
    Article Snippet: The cells were subsequently washed three times with PBS and observed and imaged under a fluorescence microscope (CKX53, Olympus, Japan).



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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Image Search Results


    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain

    Journal: BMC Oral Health

    Article Title: Dose-dependent effects of Metformin on proliferation and odontogenic differentiation of dental pulp stem cells

    doi: 10.1186/s12903-026-08221-w

    Figure Lengend Snippet: Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain

    Article Snippet: Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14.

    Techniques: Staining, Cell Culture, Control, Microscopy, Software, Derivative Assay