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hla-a*02:01 dimeric protein (ig : dimerx  (Becton Dickinson)

 
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    Structured Review

    Becton Dickinson hla-a*02:01 dimeric protein (ig : dimerx
    Dose-Dependence and Similarity Amongst HLA-A*02-restricted Epitopes from Coronavirus. (A) In vitro reactivity of HLA-A*02-restricted peptides derived from HCoV-NL63, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 in the peptide microarray for two <t>HLA-A*02:01:Ig</t> concentrations (1μg/mL and 10μg/mL), expressed as individual values (upper panel) and mean with standard deviation (lower panel). (B) Lollipop graphs for the percentage of HLA-A2*01-restricted reactive peptides and mean of peptide reactivity in different species of coronaviruses (HCoV-NL63, MERS-CoV, SARS-CoV-1 and SARS-CoV-2) for 10ug/mL (C) . Percentage of HLA-A*02 reactive peptides in the peptide microarray that are shared between two or more species of coronaviruses included in this study (D) . (E) Venn diagram with total number of reactive HLA-A*02 peptides derived from HCoV-NL63, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 and shared between two or more species of coronaviruses. Regions of peptide overlapping are highlighted by colors (red – MERS-CoV; green – SARS-CoV-1; blue – HCoV-NL63; yellow – SARS-CoV-2).
    Hla A*02:01 Dimeric Protein (Ig : Dimerx, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pepperchip+microarray+slide/pmc10656734-34-21-28?v=Becton+Dickinson
    Average 90 stars, based on 1 article reviews
    hla-a*02:01 dimeric protein (ig : dimerx - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Surveillance of SARS-CoV-2 immunogenicity: loss of immunodominant HLA-A*02-restricted epitopes that activate CD8 + T cells"

    Article Title: Surveillance of SARS-CoV-2 immunogenicity: loss of immunodominant HLA-A*02-restricted epitopes that activate CD8 + T cells

    Journal: Frontiers in Immunology

    doi: 10.3389/fimmu.2023.1229712

    Dose-Dependence and Similarity Amongst HLA-A*02-restricted Epitopes from Coronavirus. (A) In vitro reactivity of HLA-A*02-restricted peptides derived from HCoV-NL63, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 in the peptide microarray for two HLA-A*02:01:Ig concentrations (1μg/mL and 10μg/mL), expressed as individual values (upper panel) and mean with standard deviation (lower panel). (B) Lollipop graphs for the percentage of HLA-A2*01-restricted reactive peptides and mean of peptide reactivity in different species of coronaviruses (HCoV-NL63, MERS-CoV, SARS-CoV-1 and SARS-CoV-2) for 10ug/mL (C) . Percentage of HLA-A*02 reactive peptides in the peptide microarray that are shared between two or more species of coronaviruses included in this study (D) . (E) Venn diagram with total number of reactive HLA-A*02 peptides derived from HCoV-NL63, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 and shared between two or more species of coronaviruses. Regions of peptide overlapping are highlighted by colors (red – MERS-CoV; green – SARS-CoV-1; blue – HCoV-NL63; yellow – SARS-CoV-2).
    Figure Legend Snippet: Dose-Dependence and Similarity Amongst HLA-A*02-restricted Epitopes from Coronavirus. (A) In vitro reactivity of HLA-A*02-restricted peptides derived from HCoV-NL63, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 in the peptide microarray for two HLA-A*02:01:Ig concentrations (1μg/mL and 10μg/mL), expressed as individual values (upper panel) and mean with standard deviation (lower panel). (B) Lollipop graphs for the percentage of HLA-A2*01-restricted reactive peptides and mean of peptide reactivity in different species of coronaviruses (HCoV-NL63, MERS-CoV, SARS-CoV-1 and SARS-CoV-2) for 10ug/mL (C) . Percentage of HLA-A*02 reactive peptides in the peptide microarray that are shared between two or more species of coronaviruses included in this study (D) . (E) Venn diagram with total number of reactive HLA-A*02 peptides derived from HCoV-NL63, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 and shared between two or more species of coronaviruses. Regions of peptide overlapping are highlighted by colors (red – MERS-CoV; green – SARS-CoV-1; blue – HCoV-NL63; yellow – SARS-CoV-2).

    Techniques Used: In Vitro, Derivative Assay, Peptide Microarray, Standard Deviation



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    Image Search Results


    Schematic representation of the study design, microarray protocol, and data analysis. ( a ) Sample acquisition and heat inactivation of virus, ( b ) SARS-CoV-2 whole proteome microarray design, ( c ) microarray staining and image acquisition, ( d ) data analysis pipeline.

    Journal: Viruses

    Article Title: Humoral Immune Response Profile of COVID-19 Reveals Severity and Variant-Specific Epitopes: Lessons from SARS-CoV-2 Peptide Microarray

    doi: 10.3390/v15010248

    Figure Lengend Snippet: Schematic representation of the study design, microarray protocol, and data analysis. ( a ) Sample acquisition and heat inactivation of virus, ( b ) SARS-CoV-2 whole proteome microarray design, ( c ) microarray staining and image acquisition, ( d ) data analysis pipeline.

    Article Snippet: PEPperCHIP ® Peptide Microarray slides were brought to room temperature, assembled onto the PEPperCHIP ® incubation tray (PEPperPRINT GmbH, Germany), and equilibrated using the staining buffer for 15 min.

    Techniques: Microarray, Virus, Staining

    Heatmaps for IgA and IgG response showing major immunogenic regions identified in the SARS-CoV-2 whole proteome microarray. The printed proteome constitutes ORF1a/b polyprotein encoding 16 non-structural proteins (1–10 and 12–16), structural proteins (S, N, E, and M), and the accessory proteins (ORF3a, 6, 7a, 8, and 10).

    Journal: Viruses

    Article Title: Humoral Immune Response Profile of COVID-19 Reveals Severity and Variant-Specific Epitopes: Lessons from SARS-CoV-2 Peptide Microarray

    doi: 10.3390/v15010248

    Figure Lengend Snippet: Heatmaps for IgA and IgG response showing major immunogenic regions identified in the SARS-CoV-2 whole proteome microarray. The printed proteome constitutes ORF1a/b polyprotein encoding 16 non-structural proteins (1–10 and 12–16), structural proteins (S, N, E, and M), and the accessory proteins (ORF3a, 6, 7a, 8, and 10).

    Article Snippet: PEPperCHIP ® Peptide Microarray slides were brought to room temperature, assembled onto the PEPperCHIP ® incubation tray (PEPperPRINT GmbH, Germany), and equilibrated using the staining buffer for 15 min.

    Techniques: Microarray