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rodent pathogens  (IDEXX)


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    Structured Review

    IDEXX rodent pathogens
    Rodent Pathogens, supplied by IDEXX, used in various techniques. Bioz Stars score: 96/100, based on 291 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pathogen/IMPACT/pm42754287-196-10-15
    Average 96 stars, based on 291 article reviews
    rodent pathogens - by Bioz Stars, 2026-11
    96/100 stars

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    Related Articles

    other:

    Article Title: IgM promotes antitumor immunity to a Tn-expressing solid tumor.
    Article Snippet: CMT93 and CMT93- Cosmc− cells were tested for Mycoplasma and rodent pathogens (IMPACT IV testing, IDEXX- RADIL) prior to expansion and aliquot freeze- down for use in mice.

    Article Title: Simulation-guided non-thermal low-intensity ultrasound reprograms the tumor immune microenvironment and engages systemic antitumor immunity in a syngeneic orthotopic mouse model of breast cancer
    Article Snippet: Cells tested negative for mycoplasma and mouse pathogens (IMPACT II Test, IDEXX Bioanalytics, Westbrook, USA) and were used in passages 3-4.

    Article Title: PSMA binding of carbamate-containing peptidomimetics influenced by side chain length and stereocenter configuration in preclinical prostate cancer model.
    Article Snippet: To explore how core backbone modifications influence prostate-specific membrane antigen (PSMA) targeting, we synthesized a series of novel peptidomimetics replacing the classic urea linkage of established radiotracers with a carbamate functionality.. This panel systematically varied side chain length (aspartic vs. aminoadipic acid), stereocenter configuration (S/S vs. S/R diastereomers), and the radiometal chelator (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid [DOTA] vs. N,N′-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N′diacetic acid [HBED-CC]).. In vitro binding assays in LNCaP cells revealed that the carbamate backbone severely compromised PSMA affinity (Ki) for short-chain aspartic acid derivatives, whereas long-chain aminoadipic acid conjugates successfully retained low-nanomolar potencies.

    Article Title: Methods and compositions for treating cancer with von Willebrand factor peptide linked to immunotherapeutic antibodies
    Article Snippet: All cell lines used in this study were checked for mycoplasma contamination by IMPACT I pathogen test (IDEXX BioResearch).

    Polymerase Chain Reaction:

    Article Title: Methods and compositions for treating cancer with cancer-targeted adjuvants
    Article Snippet: SDS-PAGE was performed on 4-20% gradient gels (Bio-Rad) using antibody of a standard curve (2, 1.5, 1, and 0.5 mg/mL) and two dilutions of antibody-pManTLR7 conjugate samples were reduced with 10 mM dithiothreitol. .. All cell lines were tested to confirm a lack of murine pathogens via IMPACT I PCR testing (IDEXX Laboratories). .. Band density of reduced sample and antibody standard curve was then analyzed using ImageJ and antibody concentration of sample was calculated based on intensity, using standard curve generated.

    Article Title: Coordinated immune activation following KRAS inhibition in syngeneic models reveals molecular pathways that potentiate and limit antitumor immunity
    Article Snippet: .. Cell authentication and screening for rodent pathogens and mycoplasma were performed by IDEXX BioAnalytics using the IMPACT VIII PCR Profile and CellCheck mouse STR profile. ..

    Cell Culture:

    Article Title: Four new mouse models of Duchenne muscular dystrophy with clinically relevant exon deletions in the human DMD gene
    Article Snippet: .. ES cells were cultured in a laboratory utilizing materials that passed the ‘IMPACT 2’ mouse pathogen test (IDEXX BioAnalytix). ..

    In Vivo:

    Article Title: Systematic Evaluation of Combination Strategies with Rezatapopt in p53 Y220C–Mutant Cancer Models
    Article Snippet: Mycoplasma testing was 138 performed using the Universal Mycoplasma Detection Kit (ATCC, Cat. # 30-1012K), following the 139 manufacturer’s instructions. .. Prior to in vivo use, cell lines were additionally tested for 140 pathogens at IDEXX (IMPACT MR Test). ..

    Screening:

    Article Title: Coordinated immune activation following KRAS inhibition in syngeneic models reveals molecular pathways that potentiate and limit antitumor immunity
    Article Snippet: .. Cell authentication and screening for rodent pathogens and mycoplasma were performed by IDEXX BioAnalytics using the IMPACT VIII PCR Profile and CellCheck mouse STR profile. ..



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    Image Search Results


    (A) Schematic overview of the protocol modifications incorporated into Rapid-RPIP v1 relative to the Standard RPIP workflow. Individual optimisation steps, selected to reduce turnaround time, and their estimated time savings are shown. (B) Relative abundance (%) of the ten ZymoBIOMICS-DNA/RNA mock community organisms recovered by two extraction methods (Quick-DNA/RNA, ZymoBIOMICS-DNA/RNA; mean of 2 replicates each) compared with the manufacturer theoretical composition. (C) RPKM concordance between standard and rapid cDNA synthesis protocols for RNA respiratory viruses (n = 6 organism–sample pairs). Dashed line: identity (y = x); solid line: linear regression with 95% CI. Spearman ρ and Pearson r (log₁₀-RPKM) annotated. (D) Coefficient of variation (log₁₀ scale) of RPKM values across three hybridisation times (30/60/90 min), grouped by pathogen type (Bacteria, RNA Virus, DNA Virus); n per group annotated.

    Journal: medRxiv

    Article Title: Same-day hybrid capture workflow for diagnosis and surveillance of respiratory pathogens

    doi: 10.64898/2026.10.09.26365131

    Figure Lengend Snippet: (A) Schematic overview of the protocol modifications incorporated into Rapid-RPIP v1 relative to the Standard RPIP workflow. Individual optimisation steps, selected to reduce turnaround time, and their estimated time savings are shown. (B) Relative abundance (%) of the ten ZymoBIOMICS-DNA/RNA mock community organisms recovered by two extraction methods (Quick-DNA/RNA, ZymoBIOMICS-DNA/RNA; mean of 2 replicates each) compared with the manufacturer theoretical composition. (C) RPKM concordance between standard and rapid cDNA synthesis protocols for RNA respiratory viruses (n = 6 organism–sample pairs). Dashed line: identity (y = x); solid line: linear regression with 95% CI. Spearman ρ and Pearson r (log₁₀-RPKM) annotated. (D) Coefficient of variation (log₁₀ scale) of RPKM values across three hybridisation times (30/60/90 min), grouped by pathogen type (Bacteria, RNA Virus, DNA Virus); n per group annotated.

    Article Snippet: To this end, the ZymoBIOMICS DNA/RNA Miniprep Kit for nucleic acid extraction was replaced with the Quick-DNA/RNA Pathogen Miniprep Kit (Zymo Research, R1042), and samples were processed according to the manufacturer’s instructions.

    Techniques: Extraction, cDNA Synthesis, Hybridization, Bacteria, Virus