pc 505b patch clamp amplifier (Warner Instruments)

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Warner Instruments pc 505b patch clamp amplifier
Pc 505b Patch Clamp Amplifier, supplied by Warner Instruments, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/patch-clamp+amplifiers/amplifier+clamp+patch/pm42171607-195-8-11
Average 86 stars, based on 1 article reviews

pc 505b patch clamp amplifier - by Bioz Stars, 2026-09

86/100 stars

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Membrane:

Article Title: VMP1 forms a Ca 2+ release channel essential for postnatal heartbeat.
Article Snippet: .. Membrane currents were recorded in voltage- clamp mode using a bilayer clamp amplifier (BC- 535, Warner Instruments, US) and filtered at 1 to 2 kHz. .. The signals were digitized with pClamp 10.2 software (Molecular Devices, US).

other:

Article Title: An optonanobody for reversible photoactivation of recombinant and native α7 nicotinic receptors
Article Snippet: Currents were recorded using a Clamp Amplifier OC-725D (Warner Instruments), digitized with a Digidata 1550 A and acquired with Clampe× 10 (Molecular Devices).

Article Title: Mutations in ammonia transporter RhBG that impair NH 3 /NH 4 + transport in patients with chronic kidney disease
Article Snippet: Whole-cell currents were measured using a two-electrode voltage clamp system (OC-725; Warner Instruments).

Patch Clamp:

Article Title: Ether phospholipids modulate somatosensory responses by tuning multiple receptor functions in Drosophila
Article Snippet: .. Thermistor for temperature measurement in patch-clamp , Warner instruments , TA-29. .. Olympus AC10 cantilevers for atomic force microscopy , Olympus , AC10.

Article Title: Discovery of selective JAK1/2 inhibitor H018, a phase II agent with demonstrated preclinical anti-rheumatoid arthritis activity.
Article Snippet: Janus kinase (JAK) inhibitors represent a class of oral therapeutics for rheumatoid arthritis (RA), demonstrating superior clinical efficacy compared to conventional disease-modifying antirheumatic drugs (DMARDs).. However, pan-JAK inhibitors are associated with side effects such as infections and hematologic toxicity, and selective JAK inhibitors exhibit diminished efficacy.. Guided by the dual mechanism of JAK1 selectivity driving efficacy and JAK2 inhibition to enhance anti-inflammatory effects, we employed rational drug design to develop the highly selective JAK1/2 inhibitor H018 (RAI-20), intending to improve the drug safety while simultaneously managing adverse effects within a reasonable range.

Article Title: Overexpression of small-conductance Ca2+-activated K+ channel 2 attenuates pain-like behavior in female mice with cystitis.
Article Snippet: DiI-labeled neurons were identified with an ET555/25x excitation filter (Chroma Technology). .. Recordings were performed at room temperature with a PC-505B patch-clamp amplifier (Warner Instruments) interfaced to a Digidata 1440A (Molecular Devices) acquisition system. ..

Injection:

Article Title: A voltage-dependent switch underlies efficient yet specific learning and memory
Article Snippet: .. The currents were recorded 3–5 days after cRNA injection by using two electrode voltage clamp amplifier (Warner OC 725C amplifier, Warner Instruments, Hamden, CT). .. An oocyte was placed in the recording bath containing ND96 solution and was impaled by two electrodes pulled from 1.5 mm borosilicate capillaries (Warner Instruments).

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