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whole-cell patch-clamp recordings  (MultiCell Technologies)

 
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    MultiCell Technologies whole-cell patch-clamp recordings
    Whole Cell Patch Clamp Recordings, supplied by MultiCell Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/patch+clamp+recordings/patch+clamp+recording/pmc11003949-189-2-2
    Average 90 stars, based on 1 article reviews
    whole-cell patch-clamp recordings - by Bioz Stars, 2026-11
    90/100 stars

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    Related Articles

    other:

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity.
    Article Snippet: The recent application of multicell patch-clamp technology to the study of the primate brain has considerably expanded our knowledge of its microcircuits.

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity.
    Article Snippet: The dataset from multicell patch-clamp recording possesses the potential of mapping those connectivity principles into the above transcriptomic reference based on the shared morphological and electrophysiological message (dotted line with arrow in E).

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity
    Article Snippet: Multicell whole-cell patch-clamp measures synaptic strength and kinetics, synaptic properties, synaptic latency, synaptic dynamics, and synaptic plasticity.

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity
    Article Snippet: The dataset from multicell patch-clamp recording possesses the potential of mapping those connectivity principles into the above transcriptomic reference based on the shared morphological and electrophysiological message (dotted line with arrow in E ).

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity
    Article Snippet: Based on the advances in multicell patch-clamp recordings with detailed morphological reconstruction, especially the morphology of inhibitory neurons [ , ], local connectivity principles among morphology-based neuronal types will be delineated in primates as in rodents (Fig. B, ).

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity.
    Article Snippet: Multicell patch-clamp setups with up to 12 simultaneously recorded neurons were achieved before 2011 [81–83].

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity
    Article Snippet: Multicell patch-clamp setups with up to 12 simultaneously recorded neurons were achieved before 2011 [ – ].

    Extraction:

    Article Title: Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity.
    Article Snippet: .. Finally, to obtain transcriptome information from multicell patch experiments, future research should prioritize the development of techniques that enable the simultaneous patching of multiple cells, extraction of nuclei for RNA retrieval, and concurrent acquisition of morphological and electrophysiological information. ..



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    A) Schematic depicting JONs projecting through the antennal nerve and synapsing onto APN2 cells (gold dashed box) in the ipsilateral hemisphere of the central brain. Inset shows expression pattern of the genetic driver line labeling APN2 ( 24C06-GAL4) . Scale bar is 20 µm. B) During whole <t>cell</t> <t>patch</t> <t>clamp</t> <t>recordings,</t> antennal movements were recorded by a lateral camera and flight activity was monitored using an optical wingbeat detector. C) Example video frame with 2 tracked points and the relative direction of antenna angle deflections. Deflections down towards the head are represented as negative values, and deflections up and away from the head as positive values. D) Example single-trial traces showing antennal and APN2 activity during quiescence (left) and flight (right). Wing movement was detected using an infrared light sensor. E) Each dot is the average response of one APN2 cell. Black bars indicate the average across APN2 cells for each condition, with respective SEM error bars. Grey dashed lines pair measurements from the same cell during flight and quiescence. Across flies, the average APN2 membrane potential is reduced during bouts of flight compared to quiescence, both when the antennae are free (paired t-test; p = 0.037) and when the antennae are glued (Wilcoxon Signed-Rank Test; p = 0.014).
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    Image Search Results


    A) Schematic depicting JONs projecting through the antennal nerve and synapsing onto APN2 cells (gold dashed box) in the ipsilateral hemisphere of the central brain. Inset shows expression pattern of the genetic driver line labeling APN2 ( 24C06-GAL4) . Scale bar is 20 µm. B) During whole cell patch clamp recordings, antennal movements were recorded by a lateral camera and flight activity was monitored using an optical wingbeat detector. C) Example video frame with 2 tracked points and the relative direction of antenna angle deflections. Deflections down towards the head are represented as negative values, and deflections up and away from the head as positive values. D) Example single-trial traces showing antennal and APN2 activity during quiescence (left) and flight (right). Wing movement was detected using an infrared light sensor. E) Each dot is the average response of one APN2 cell. Black bars indicate the average across APN2 cells for each condition, with respective SEM error bars. Grey dashed lines pair measurements from the same cell during flight and quiescence. Across flies, the average APN2 membrane potential is reduced during bouts of flight compared to quiescence, both when the antennae are free (paired t-test; p = 0.037) and when the antennae are glued (Wilcoxon Signed-Rank Test; p = 0.014).

    Journal: bioRxiv

    Article Title: Sensory-motor integration in a nonspiking interneuron contributes to active sensor control in Drosophila

    doi: 10.64898/2026.04.16.718965

    Figure Lengend Snippet: A) Schematic depicting JONs projecting through the antennal nerve and synapsing onto APN2 cells (gold dashed box) in the ipsilateral hemisphere of the central brain. Inset shows expression pattern of the genetic driver line labeling APN2 ( 24C06-GAL4) . Scale bar is 20 µm. B) During whole cell patch clamp recordings, antennal movements were recorded by a lateral camera and flight activity was monitored using an optical wingbeat detector. C) Example video frame with 2 tracked points and the relative direction of antenna angle deflections. Deflections down towards the head are represented as negative values, and deflections up and away from the head as positive values. D) Example single-trial traces showing antennal and APN2 activity during quiescence (left) and flight (right). Wing movement was detected using an infrared light sensor. E) Each dot is the average response of one APN2 cell. Black bars indicate the average across APN2 cells for each condition, with respective SEM error bars. Grey dashed lines pair measurements from the same cell during flight and quiescence. Across flies, the average APN2 membrane potential is reduced during bouts of flight compared to quiescence, both when the antennae are free (paired t-test; p = 0.037) and when the antennae are glued (Wilcoxon Signed-Rank Test; p = 0.014).

    Article Snippet: We used 6-11 MΩ thick-walled glass pipettes (Item #1B150F-3, World Precision Instruments) for whole cell patch clamp recordings, which we pulled using a Sutter P-1000 puller.

    Techniques: Expressing, Labeling, Patch Clamp, Activity Assay, Membrane