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Burleigh Instruments micromanipulators patch clamp driver pcs-250
Micromanipulators Patch Clamp Driver Pcs 250, supplied by Burleigh Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/patch+clamp+micromanipulator/micromanipulators+patch+clamp+driver+pcs+250/pm10734047-77-8-13
Average 90 stars, based on 1 article reviews
micromanipulators patch clamp driver pcs-250 - by Bioz Stars, 2026-10
90/100 stars

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Article Title: New products
Article Snippet: Taylor & Francis makes every effort to ensure the accuracy of all the information (the “Content”) contained in the publications on our platform.. However, Taylor & Francis, our agents, and our licensors make no representations or warranties whatsoever as to the accuracy, completeness, or suitability for any purpose of the Content.. Any opinions and views expressed in this publication are the opinions and views of the authors, and are not the views of or endorsed by Taylor & Francis.

Article Title: Cl- current in IMCD cells activated by hypotonicity: time course, ATP dependence, and inhibitors
Article Snippet: Volk, Kenneth A., Chong Zhang, Russell F. Husted, and John B. Stokes.. Clcurrent in IMCD cells activated by hypotonicity: time course, ATP dependence, and inhibitors.. Am.

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Article Title: Activation and inactivation of mechanosensitive currents in the chick heart.
Article Snippet: The behavior of MS channels in embryonic chick ventricular myocytes activated by direct mechanical stimulation is strongly affected by inactivation.. The amplitude of the current is dependent not only on the amplitude of the stimulus, but also the history of stimulation.. The MS current inactivation appears to be composed of at least two contributions: (i) rearrangement of the cortical tension transducing elements and (ii) blocking action of an autocrine agent released from the cell.

Patch Clamp:

Article Title: Amine weak bases disrupt vesicular storage and promote exocytosis in chromaffin cells.
Article Snippet: The vesicular contents in bovine chromaffin cells are maintained at high levels owing to the strong association of its contents, which is promoted by the low vesicular pH.. The association is among the catecholamines, Ca, ATP, and vesicular proteins.. It was found that transient application of a weak base, methylamine (30 mM ), amphetamine (10 mM ), or tyramine (10 mM ), induced exocytotic release.

Article Title: Vesicular Ca(2+) participates in the catalysis of exocytosis.
Article Snippet: .. The carbon-fiber microelectrode and micropipette were mounted on micromanipulators (Patch Clamp Driver PCS-250, Burleigh, Instruments Inc., Fishers, NY). ..



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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a <t>micromanipulator.</t> The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].
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Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a micromanipulator. The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].

Journal: Bio-protocol

Article Title: Optogenetic Approach for Investigating Descending Control of Nociception in Ex Vivo Spinal Cord Preparation

doi: 10.21769/BioProtoc.5483

Figure Lengend Snippet: Left: Overview of the experimental setup showing perfusion inflow and outflow tubing, a low-magnification objective, a high-magnification water-immersion objective, and both white and infrared (IR)-LEDs mounted on a micromanipulator. The LEDs should be connected to an adjusted power supply unit and positioned so that their beams strike the plane of the experimental chamber at a 10–20° angle. Note that the LEDs must remain above the bath solution and should not be submerged. Right: Overview of spinal cord preparation in the experimental chamber. The ex vivo spinal cord preparation is affixed to a metal plate at an approximately 45° angle so that the dorsal horn is on top. The spared dorsal root is connected to a suction electrode and is slightly pulled to reveal the underlying dorsal horn. Modified from [17].

Article Snippet: Patch clamp micromanipulator (Scientifica, model: PatchStar) 5.

Techniques: Ex Vivo, Modification