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p src  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc p src
    P Src, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 46 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p+src/Phospho-Src+(Ser17)+Rabbit+mAb/pm41923217-130-22-23
    Average 94 stars, based on 46 article reviews
    p src - by Bioz Stars, 2026-11
    94/100 stars

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    other:

    Article Title: miR-484 sensitizes in IDH-wild and IDH-mutant glioblastoma cells to temozolomide by inhibiting oncogenic FOXM1 signaling.
    Article Snippet: After washing with TBS-T, the membranes were probed with the following primary antibodies: FOXM1 (Cell signaling, cat# 5436S), Integrinβ1 (Proteintech, cat# 12594-1-Ap), p-Src (Cell signaling, cat# 12432S), Src (Proteintech, cat# 11097-1-Ap), pFAK (Cell signaling, cat# 8556S), FAK (Proteintech, cat# 12636-1-Ap), PARP (Proteintech, cat# 13371-1-Ap), cyclin-D1 (Proteintech, cat# 55004-1-Ap) and β-actin (Proteintech, cat# 60008-1-Ig).

    Article Title: Enhanced In Vitro and In Vivo Autophagy Suppression via LC3 siRNA-Loaded “Smart” Nanoparticles and Doxorubicin Combination Therapy in Triple Negative Breast Cancer
    Article Snippet: Antibody Name Company (Catalog No.) Dilution Anti-LC3B Abbkine (Abp57204-2) 1:1000 Anti-Integrin beta 1 Proteintech(12594-1-AP) 1:1000 Anti-Src Proteintech(11097-1-AP) 1:1000 Anti-phospho-Src Cell Signaling Technology (12432S) 1:1000 Anti-Cleaved-Caspase3 Elabscience(E-AB-30003) 1:1000 Anti-Caspase3 Elabscience(E-AB-63602) 1:1000 Anti-β-Actin Proteintech (60008-1-IG) 1:2000 Anti-cyclin D1 Proteintech (55004-1-AP) 1:1000 Anti-PARP Cell Signaling Technology (9542S) 1:1000

    Cell-Signaling:

    Article Title: FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity
    Article Snippet: Src , Cell Signaling Technology , Cat# 2109; RRID: AB_2106059. .. p -Src , Cell Signaling Technology , Cat# 12432; RRID: AB_2797910. .. p -MLC , Cell Signaling Technology , Cat# 3671; RRID: AB_330248.

    Article Title: Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
    Article Snippet: Overexpression of EphB3 has been documented across various cancers and essential for cell proliferation, survive and metastasis, making it a valuable therapeutic target.. In this study, a series of novel penta-1,4-dien-3-one and quinoxaline conjugates were designed and synthesized using pharmacophore fusion strategies to explore potential EphB3 inhibitors.. CCK-8 experiments revealed significant anti-cancer activity of most newly synthesized compounds against hepatocellular carcinoma (HCC).

    Article Title: Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia
    Article Snippet: .. Cell lines were stimulated with 10 ng/mL CCL2 and whole cell lysates were analyzed by immunoblotting for detection of phospho-MEK1/2 (Ser221; Cell Signaling Technologies, No. 2338), phospho-ERK1/2 (Thr202/Tyr204; Cell Signaling Technologies, No. 4377), phospho-JNK1/JNK2 (Thr183/Tyr185; Thermo Fisher Scientific, No. 700031), phospho-SRC (Ser17; Cell Signalling Technologies, No. 12432), phospho-Rb (Ser780; Cell Signaling Technologies, No. 8180), phospho-P70 S6 (Thr421/Ser424; Cell Signaling Technologies, No. 9204), phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199; Cell Signaling Technologies, No. 17366), phospho-STAT5 (Tyr694; Cell Signaling Technologies, No. 9314), and phospho-AKT (Ser473; Cell Signaling Technologies, No. 4058). .. The phosphoprotein levels were normalized to the respective total protein using densitometric analysis from ImageLab software. β-Actin (13E5; Cell Signaling Technologies, No. 4970), GAPDH (14C10; Cell Signaling Technologies, No. 2118) or Vinculin (E1E9V; Cell Signaling Technologies, No. 13901) were used as protein loading controls.

    Western Blot:

    Article Title: Endomucin selectively regulates vascular endothelial growth factor receptor-2 endocytosis through its interaction with AP2
    Article Snippet: BioTraceTM NT Nitrocellulose Transfer Membrane 30 cm × 3 m roll (#27376–991) was purchased from Fisher Scientific. .. Immunoblots were probed with rabbit anti-p-VEGFR2-Y1175 (1:1,000, Cell Signaling, #2478S), rabbit anti-Src (1:1,000, Cell Signaling, #2109S), rabbit anti-pSrc-Ser17 (1:1,000, Cell Signaling, #12432), rabbit anti-FAK (1:1,000, Novus Biologicals, #NBP2-67327), rabbit anti-p-FAK-Y397 (1:1,000, Abcam, #ab81298), rabbit anti-p-ERK1/2 Y204/ T202 (1:1,000, Cell Signaling, #4370S), mouse anti-ERK1/2 (1:1,000, Cell Signaling, #4696S), rabbit anti-VEGFR2 (1:1,000, Cell Signaling, #2479S), goat anti-VEGFR1 (1:1000, R&D Systems #AF321), rabbit anti-FGFR1 (1:1000, Cell Signaling, #9740S), mouse anti-Myc (1:1000, Cell Signaling, #9B11) and mouse anti-CD31 (1:1,000, Thermo Fisher, #14–0311-81). .. Secondary antibodies used include goat anti-rabbit 800CW (1:20,000, Li-cor, #925–32211), goat anti-mouse 680RD (1:20,000, Li-cor, #925–68070), donkey anti-goat 800CW (1:20,000, Li-cor, #926–32214) goat anti-rabbit horseradish peroxidase (HRP) conjugated (1:1000, R&D Systems #HAF008), goat anti-mouse HRP conjugated (1:1000, R&D Systems #HAF007), and donkey anti-goat HRP conjugated (1:1000, R&D Systems #HAF109).

    Article Title: Targeting CCL2/CCR2 signaling overcomes MEK inhibitor resistance in Acute Myeloid Leukemia
    Article Snippet: .. Cell lines were stimulated with 10 ng/mL CCL2 and whole cell lysates were analyzed by immunoblotting for detection of phospho-MEK1/2 (Ser221; Cell Signaling Technologies, No. 2338), phospho-ERK1/2 (Thr202/Tyr204; Cell Signaling Technologies, No. 4377), phospho-JNK1/JNK2 (Thr183/Tyr185; Thermo Fisher Scientific, No. 700031), phospho-SRC (Ser17; Cell Signalling Technologies, No. 12432), phospho-Rb (Ser780; Cell Signaling Technologies, No. 8180), phospho-P70 S6 (Thr421/Ser424; Cell Signaling Technologies, No. 9204), phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199; Cell Signaling Technologies, No. 17366), phospho-STAT5 (Tyr694; Cell Signaling Technologies, No. 9314), and phospho-AKT (Ser473; Cell Signaling Technologies, No. 4058). .. The phosphoprotein levels were normalized to the respective total protein using densitometric analysis from ImageLab software. b-Actin (13E5; Cell Signaling Technologies, No. 4970), GAPDH (14C10; Cell Signaling Technologies, No. 2118) or Vinculin (E1E9V; Cell Signaling Technologies, No. 13901) were used as protein loading controls.

    Article Title: Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia
    Article Snippet: .. Cell lines were stimulated with 10 ng/mL CCL2 and whole cell lysates were analyzed by immunoblotting for detection of phospho-MEK1/2 (Ser221; Cell Signaling Technologies, No. 2338), phospho-ERK1/2 (Thr202/Tyr204; Cell Signaling Technologies, No. 4377), phospho-JNK1/JNK2 (Thr183/Tyr185; Thermo Fisher Scientific, No. 700031), phospho-SRC (Ser17; Cell Signalling Technologies, No. 12432), phospho-Rb (Ser780; Cell Signaling Technologies, No. 8180), phospho-P70 S6 (Thr421/Ser424; Cell Signaling Technologies, No. 9204), phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199; Cell Signaling Technologies, No. 17366), phospho-STAT5 (Tyr694; Cell Signaling Technologies, No. 9314), and phospho-AKT (Ser473; Cell Signaling Technologies, No. 4058). .. The phosphoprotein levels were normalized to the respective total protein using densitometric analysis from ImageLab software. β-Actin (13E5; Cell Signaling Technologies, No. 4970), GAPDH (14C10; Cell Signaling Technologies, No. 2118) or Vinculin (E1E9V; Cell Signaling Technologies, No. 13901) were used as protein loading controls.

    Article Title: Peptide KN-17-Loaded Supramolecular Hydrogel Induces the Regeneration of the Pulp-Dentin Complex.
    Article Snippet: Regenerating the pulp-dentin complex remains a decisive factor during apexification for immature permanent teeth.. Peptide KN-17, which was modified based on the structure of cecropin B, could effectively interfere with bacterial growth and induce the migration of human bone marrow stromal cells (hBMSCs).. This study aimed to investigate the effect of KN-17 on the tissue regeneration.



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    Effects <t>of</t> <t>SRC</t> gene silencing on HT29 cell proliferation and migration and its regulatory mechanisms (A) Transwell results for the normal group and the si‐SRC group. (B) Immunofluorescence findings of Ki67 for both the normal and si‐SRC groups. (C) Western blot analysis results for p‐PI3K, p‐AKT <t>and</t> <t>p‐SRC</t> across all groups.
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    Image Search Results


    Effects of SRC gene silencing on HT29 cell proliferation and migration and its regulatory mechanisms (A) Transwell results for the normal group and the si‐SRC group. (B) Immunofluorescence findings of Ki67 for both the normal and si‐SRC groups. (C) Western blot analysis results for p‐PI3K, p‐AKT and p‐SRC across all groups.

    Journal: IET Systems Biology

    Article Title: Decoding the Anti‐Tumour Mechanism of ɑ‐Solanine: SRC Inhibition and Ferroptosis Induction in Colon Cancer

    doi: 10.1049/syb2.70057

    Figure Lengend Snippet: Effects of SRC gene silencing on HT29 cell proliferation and migration and its regulatory mechanisms (A) Transwell results for the normal group and the si‐SRC group. (B) Immunofluorescence findings of Ki67 for both the normal and si‐SRC groups. (C) Western blot analysis results for p‐PI3K, p‐AKT and p‐SRC across all groups.

    Article Snippet: Primary antibodies were obtained from ABclonal: p‐SRC (AP1027), p‐PI3K (AP0427), p‐AKT (AP0637) and β‐actin (AC026).

    Techniques: Migration, Immunofluorescence, Western Blot