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Precision Biologic Inc normal human plasma
Analysis of cetacean <t>plasma.</t> (A) Activated partial thromboplastin time studies. White bars show average aPTTs of pooled <t>normal</t> <t>human</t> plasma and plasma from a cetacean (a false killer whale). Gray bars show average aPTTs for plasmas from human patients lacking FXII (−XII), FXI (−XI), PK (−PK), or HK (−HK). Black bars indicate average aPTTs for mixtures of equal volumes of human factor-deficient plasmas and false killer whale plasma. Note the normal clotting times for mixtures with human plasma lacking FXI and HK. Bars represent averages of 3 runs for each plasma. (B) Plasma western blots. One-microliter samples of plasma from a false killer whale (F), a human (H), and a mouse (M) were size fractionated by SDS-PAGE and transferred to nitrocellulose. Protein controls (C) for human FXII (XII), FXI (XI), PK, or HK were included. Blots were developed with polyclonal IgGs to each human protein (left column) or monoclonal antibodies raised against mouse FXII (1D7 and 15D10, center column) or mouse FXI (14E11 and 15B4, right column). Note the absence of signals for FXII or PK, and the presence of FXI and HK, in plasma from the false killer whale.
Normal Human Plasma, supplied by Precision Biologic Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/normal+human+reference+plasma/normal+human+plasma/pmc07757006-45-0-4
Average 90 stars, based on 1 article reviews
normal human plasma - by Bioz Stars, 2026-09
90/100 stars

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1) Product Images from "The evolution of factor XI and the kallikrein-kinin system"

Article Title: The evolution of factor XI and the kallikrein-kinin system

Journal: Blood Advances

doi: 10.1182/bloodadvances.2020002456

Analysis of cetacean plasma. (A) Activated partial thromboplastin time studies. White bars show average aPTTs of pooled normal human plasma and plasma from a cetacean (a false killer whale). Gray bars show average aPTTs for plasmas from human patients lacking FXII (−XII), FXI (−XI), PK (−PK), or HK (−HK). Black bars indicate average aPTTs for mixtures of equal volumes of human factor-deficient plasmas and false killer whale plasma. Note the normal clotting times for mixtures with human plasma lacking FXI and HK. Bars represent averages of 3 runs for each plasma. (B) Plasma western blots. One-microliter samples of plasma from a false killer whale (F), a human (H), and a mouse (M) were size fractionated by SDS-PAGE and transferred to nitrocellulose. Protein controls (C) for human FXII (XII), FXI (XI), PK, or HK were included. Blots were developed with polyclonal IgGs to each human protein (left column) or monoclonal antibodies raised against mouse FXII (1D7 and 15D10, center column) or mouse FXI (14E11 and 15B4, right column). Note the absence of signals for FXII or PK, and the presence of FXI and HK, in plasma from the false killer whale.
Figure Legend Snippet: Analysis of cetacean plasma. (A) Activated partial thromboplastin time studies. White bars show average aPTTs of pooled normal human plasma and plasma from a cetacean (a false killer whale). Gray bars show average aPTTs for plasmas from human patients lacking FXII (−XII), FXI (−XI), PK (−PK), or HK (−HK). Black bars indicate average aPTTs for mixtures of equal volumes of human factor-deficient plasmas and false killer whale plasma. Note the normal clotting times for mixtures with human plasma lacking FXI and HK. Bars represent averages of 3 runs for each plasma. (B) Plasma western blots. One-microliter samples of plasma from a false killer whale (F), a human (H), and a mouse (M) were size fractionated by SDS-PAGE and transferred to nitrocellulose. Protein controls (C) for human FXII (XII), FXI (XI), PK, or HK were included. Blots were developed with polyclonal IgGs to each human protein (left column) or monoclonal antibodies raised against mouse FXII (1D7 and 15D10, center column) or mouse FXI (14E11 and 15B4, right column). Note the absence of signals for FXII or PK, and the presence of FXI and HK, in plasma from the false killer whale.

Techniques Used: Clinical Proteomics, Coagulation, Western Blot, SDS Page, Bioprocessing

Related Articles

Clinical Proteomics:

Article Title: The evolution of factor XI and the kallikrein-kinin system
Article Snippet: Normal human plasma (Precision Biologics); human plasmas lacking PK, FXII, HK, or FXI (George King Biomed); and plasma from a false killer whale (Vancouver Aquarium) were anticoagulated with sodium citrate. .. Normal human plasma (Precision Biologics); human plasmas lacking PK, FXII, HK, or FXI (George King Biomed); and plasma from a false killer whale (Vancouver Aquarium) were anticoagulated with sodium citrate. .. Human FXII, FXIIa, PK, HK, and FIX were from Enzyme Research Laboratories and FXI and α-thrombin were from Haematologic Industries.

Article Title: Non-criteria antiphospholipid antibodies and pediatric rheumatic disease: a case series.
Article Snippet: PTT testing and dRVVT reagents were manufactured by Stago (Parsippany, NJ). .. Normal human plasma was obtained from Precision Biologics (Dallas, TX). ..

Article Title: Discordant Partial Thromboplastin Time (PTT) vs Anti-Xa Heparin Activity.
Article Snippet: Owren-Koller buffer was obtained from Diagnostica Stago. .. Pooled normal citrate plasma and factor XII–deficient plasma were obtained from PrecisionBiologics. ..

Article Title: Diagnosis and management of factor XI alloinhibitors in patients with congenital factor XI deficiency-A large single-centre experience.
Article Snippet: Correspondence Kirollos Salah Kamel, Katharine Dormandy Haemophilia Centre, Royal Free Hospital NHS Trust, Pond Street, London, NW3 2QG, UK.. Email: Kirollos.Kamel@nhs.net Abstract Introduction: Factor (F) XI deficiency is an inherited bleeding disorder with increased prevalence in Ashkenazi Jews where it is mainly caused by two variants, p.Glu135* (type II, leading to a null allele) and p.Phe301Leu (type III, missense variant).. Inhibitor development is rare, and only seen in severe FXI deficiency (<20 IU/dL) upon exposure to plasma-based products.

Article Title: Genetics and Hemostatic Potential in Persons with Mild to Moderate Hemophilia A with a Discrepancy between One-Stage and Chromogenic FVIII Assays.
Article Snippet: 1Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden 2Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden 3Hemostasis Department and Hemophilia Center, Blood Transfusion Institute of Serbia, Belgrade, Serbia 4Coagulation Unit, Department of Hematology, Karolinska University Hospital, Stockholm, Sweden 5Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden

Article Title: Coagulation assay discrepancies in Japanese patients with non-severe hemophilia A.
Article Snippet: Patients with non-severe hemophilia A often show discrepancies in factor VIII (FVIII) activity.. However, information on variant-specific coagulation assay characteristics in Japanese patients is limited.. Pathogenic variants were classified into three groups, thrombin-cleavage site (TC), A1-A2-A3 interface (IF), and non-discrepant, with reference to previous studies.

Article Title: Towards Biohybrid Lung Development—Fibronectin-Coating Bestows Hemocompatibility of Gas Exchange Hollow Fiber Membranes by Improving Flow-Resistant Endothelialization
Article Snippet: .. In parallel, AH or FN coated, but non-endothelialized HFM samples were immersed in normal blood plasma (Precision BioLogic Inc., Dartmouth, NS, Canada) at 37 °C for 6 h to serve as clinically relevant positive control (PC), mimicking the result of the inevitable contact of the HFM and the circulating blood, which initiates inflammatory responses and thrombus formation in the clinical setting. ..

other:

Article Title: The evolution of factor XI and the kallikrein-kinin system
Article Snippet: Human FXII, FXIIa, PK, HK, and FIX were from Enzyme Research Laboratories and FXI and α-thrombin were from Haematologic Industries.

Positive Control:

Article Title: Towards Biohybrid Lung Development—Fibronectin-Coating Bestows Hemocompatibility of Gas Exchange Hollow Fiber Membranes by Improving Flow-Resistant Endothelialization
Article Snippet: .. In parallel, AH or FN coated, but non-endothelialized HFM samples were immersed in normal blood plasma (Precision BioLogic Inc., Dartmouth, NS, Canada) at 37 °C for 6 h to serve as clinically relevant positive control (PC), mimicking the result of the inevitable contact of the HFM and the circulating blood, which initiates inflammatory responses and thrombus formation in the clinical setting. ..



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