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nonparametric mann-whitney test using graphpad prism 9.4.0 software  (GraphPad Software Inc)


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    GraphPad Software Inc nonparametric mann-whitney test using graphpad prism 9.4.0 software
    CAM13K SOSIP immunization elicits neutralizing antibody responses in V2-apex bNAb precursor expressing knock-in mice. (A) CH01_RUA heavy chain (HC)-only knock-in mice  were immunized either with 20 μg CAM13K SOSIP trimer in 5 μg GLA-SE adjuvant ( n = 5) or with 5 μg GLA-SE adjuvant alone ( n = 3). Time points of immunization and bleeds are indicated. (B) Comparison of serum neutralization titers (reciprocal 50% inhibitory dilutions, ID 50 ) from trimer-immunized (red circles) and adjuvant-only (blue squares) knock-in mice (preimmunization and terminal bleeds are shown as open and filled symbols, respectively). Serum neutralizing activity was tested in the TZM-bl assay  against pseudoviruses carrying the immunogen-matched autologous CAM13K Env, three CH01_RUA sensitive HIV-1 Envs (C1080, CRF250, Q23), as well as N160 glycan knockout variants of CRF250 and Q23. MLV Env containing pseudovirus was used for control. Differences between immunized and adjuvant-only groups were assessed using a nonparametric Mann-Whitney test (Prism 9.4.0 GraphPad Software), with asterisks indicating P < 0.05.
    Nonparametric Mann Whitney Test Using Graphpad Prism 9.4.0 Software, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nonparametric+testing+software/mann+whitney+test+graphpad+prism/pmc09973348-302-17-16
    Average 90 stars, based on 1 article reviews
    nonparametric mann-whitney test using graphpad prism 9.4.0 software - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies"

    Article Title: A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies

    Journal: mBio

    doi: 10.1128/mbio.03370-22

    CAM13K SOSIP immunization elicits neutralizing antibody responses in V2-apex bNAb precursor expressing knock-in mice. (A) CH01_RUA heavy chain (HC)-only knock-in mice  were immunized either with 20 μg CAM13K SOSIP trimer in 5 μg GLA-SE adjuvant ( n = 5) or with 5 μg GLA-SE adjuvant alone ( n = 3). Time points of immunization and bleeds are indicated. (B) Comparison of serum neutralization titers (reciprocal 50% inhibitory dilutions, ID 50 ) from trimer-immunized (red circles) and adjuvant-only (blue squares) knock-in mice (preimmunization and terminal bleeds are shown as open and filled symbols, respectively). Serum neutralizing activity was tested in the TZM-bl assay  against pseudoviruses carrying the immunogen-matched autologous CAM13K Env, three CH01_RUA sensitive HIV-1 Envs (C1080, CRF250, Q23), as well as N160 glycan knockout variants of CRF250 and Q23. MLV Env containing pseudovirus was used for control. Differences between immunized and adjuvant-only groups were assessed using a nonparametric Mann-Whitney test (Prism 9.4.0 GraphPad Software), with asterisks indicating P < 0.05.
    Figure Legend Snippet: CAM13K SOSIP immunization elicits neutralizing antibody responses in V2-apex bNAb precursor expressing knock-in mice. (A) CH01_RUA heavy chain (HC)-only knock-in mice were immunized either with 20 μg CAM13K SOSIP trimer in 5 μg GLA-SE adjuvant ( n = 5) or with 5 μg GLA-SE adjuvant alone ( n = 3). Time points of immunization and bleeds are indicated. (B) Comparison of serum neutralization titers (reciprocal 50% inhibitory dilutions, ID 50 ) from trimer-immunized (red circles) and adjuvant-only (blue squares) knock-in mice (preimmunization and terminal bleeds are shown as open and filled symbols, respectively). Serum neutralizing activity was tested in the TZM-bl assay against pseudoviruses carrying the immunogen-matched autologous CAM13K Env, three CH01_RUA sensitive HIV-1 Envs (C1080, CRF250, Q23), as well as N160 glycan knockout variants of CRF250 and Q23. MLV Env containing pseudovirus was used for control. Differences between immunized and adjuvant-only groups were assessed using a nonparametric Mann-Whitney test (Prism 9.4.0 GraphPad Software), with asterisks indicating P < 0.05.

    Techniques Used: Expressing, Knock-In, Neutralization, Activity Assay, Knock-Out, MANN-WHITNEY, Software

    Related Articles

    other:

    Article Title: Vaccine Induction of Heterologous HIV-1 Neutralizing Antibody B Cell Lineages in Humans
    Article Snippet: The Mann-Whitney test in GraphPad Prism v9.0 was also used to compare different outcomes, for example, the computed lipid insertion propensity scores for variable heavy chain regions between non-NAbs and NAbs in Figure 4d .

    Article Title: Assessing family history and approaches for identifying dementia patients with diagnostically significant genetic findings.
    Article Snippet: Differences in median AAO of APOE4 homozygotes were evaluated using Mann-Whitney test (GraphPad Prism 8.0.1).

    Article Title:
    Article Snippet: Statistical significance between two groups was 229 analysed using a two-tailed Mann-Whitney test (GraphPad PRISM).

    Mann-Whitney U-Test:

    Article Title: Interdependence of Pasha and Drosha for localization and function of the Microprocessor in C. elegans
    Article Snippet: .. For fertility assays, p -values were calculated using the two-tailed Mann-Whitney U test in GraphPad Prism. .. For qRT-PCR, bursting, and Western blot data analysis and in comparing total iso-miR and pre-miRNA read levels, two-tailed, two-sample Student’s t-tests were used to calculate p -values in Microsoft Excel or GraphPad Prism.

    Article Title: Quercetin modulates transcription of the apoptotic and CatSper genes and optimises post thaw viability and kinematics of buck spermatozoa.
    Article Snippet: .. The level of significance was calculated using a non-parametric Mann-Whitney U test using GraphPad Prism software. ..

    MANN-WHITNEY:

    Article Title: Autoantigen and IL-2 activated CD4 + CD25 + T regulatory cells are induced to express CD8 and are autoantigen specific in inhibiting experimental autoimmune encephalomyelitis.
    Article Snippet: Experimental autoimmune encephalomyelitis (EAE) induced by immunization with myelin basic protein (MBP) is a self-limiting disease model of multiple sclerosis.. CD4CD25Foxp3T cells play a role in limiting autoimmune disease but treatment with antigen naïve CD4CD25 cells does not reduce EAE.. This study examined if in vitro activation by MBP and rIL-2 induced CD4CD25Foxp3 cells that could inhibit EAE.

    Software:

    Article Title: Quercetin modulates transcription of the apoptotic and CatSper genes and optimises post thaw viability and kinematics of buck spermatozoa.
    Article Snippet: .. The level of significance was calculated using a non-parametric Mann-Whitney U test using GraphPad Prism software. ..

    Article Title:
    Article Snippet: .. Statistical significance of difference in response to the non-covalent vs. covalent BTK inhibitors was analyzed using MannWhitney U test by GraphPad Prism software. ..



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    CAM13K SOSIP immunization elicits neutralizing antibody responses in V2-apex bNAb precursor expressing knock-in mice. (A) CH01_RUA heavy chain (HC)-only knock-in mice  were immunized either with 20 μg CAM13K SOSIP trimer in 5 μg GLA-SE adjuvant ( n = 5) or with 5 μg GLA-SE adjuvant alone ( n = 3). Time points of immunization and bleeds are indicated. (B) Comparison of serum neutralization titers (reciprocal 50% inhibitory dilutions, ID 50 ) from trimer-immunized (red circles) and adjuvant-only (blue squares) knock-in mice (preimmunization and terminal bleeds are shown as open and filled symbols, respectively). Serum neutralizing activity was tested in the TZM-bl assay  against pseudoviruses carrying the immunogen-matched autologous CAM13K Env, three CH01_RUA sensitive HIV-1 Envs (C1080, CRF250, Q23), as well as N160 glycan knockout variants of CRF250 and Q23. MLV Env containing pseudovirus was used for control. Differences between immunized and adjuvant-only groups were assessed using a nonparametric Mann-Whitney test (Prism 9.4.0 GraphPad Software), with asterisks indicating P < 0.05.

    Journal: mBio

    Article Title: A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies

    doi: 10.1128/mbio.03370-22

    Figure Lengend Snippet: CAM13K SOSIP immunization elicits neutralizing antibody responses in V2-apex bNAb precursor expressing knock-in mice. (A) CH01_RUA heavy chain (HC)-only knock-in mice were immunized either with 20 μg CAM13K SOSIP trimer in 5 μg GLA-SE adjuvant ( n = 5) or with 5 μg GLA-SE adjuvant alone ( n = 3). Time points of immunization and bleeds are indicated. (B) Comparison of serum neutralization titers (reciprocal 50% inhibitory dilutions, ID 50 ) from trimer-immunized (red circles) and adjuvant-only (blue squares) knock-in mice (preimmunization and terminal bleeds are shown as open and filled symbols, respectively). Serum neutralizing activity was tested in the TZM-bl assay against pseudoviruses carrying the immunogen-matched autologous CAM13K Env, three CH01_RUA sensitive HIV-1 Envs (C1080, CRF250, Q23), as well as N160 glycan knockout variants of CRF250 and Q23. MLV Env containing pseudovirus was used for control. Differences between immunized and adjuvant-only groups were assessed using a nonparametric Mann-Whitney test (Prism 9.4.0 GraphPad Software), with asterisks indicating P < 0.05.

    Article Snippet: Differences between immunized and adjuvant-only knock-in mouse groups were assessed using a nonparametric Mann-Whitney test using GraphPad Prism 9.4.0 software.

    Techniques: Expressing, Knock-In, Neutralization, Activity Assay, Knock-Out, MANN-WHITNEY, Software