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nonlinear mixed-effects modeling program nonmem version 7.5.0  (ICON plc)

 
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    ICON plc nonlinear mixed-effects modeling program nonmem version 7.5.0
    Nonlinear Mixed Effects Modeling Program Nonmem Version 7.5.0, supplied by ICON plc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nonlinear+mixed-effect+models/nonlinear+mixed+effects+modeling+software+nonmem+version+7+4+4/pm39895366-101-12-18
    Average 90 stars, based on 1 article reviews
    nonlinear mixed-effects modeling program nonmem version 7.5.0 - by Bioz Stars, 2026-10
    90/100 stars

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    Article Title: Validating Low‐Dose Iohexol as a Marker for Glomerular Filtration Rate by In Vitro and In Vivo Studies
    Article Snippet: A population PK model of iohexol was developed using the nonlinear mixed‐effects modeling program NONMEM version 7.5.0 (ICON plc, Dublin, Ireland), Perl speaks NONMEM (PsN) version 5.2.6 (Uppsala University, Uppsala, Sweden) [ ], and Pirana version 3.0.0 (Certara, Princeton, New Jersey).

    Article Title: Population Pharmacokinetics and Exposure–Response Analysis of Benralizumab in Chinese Adults, Adolescents, and Pediatric Participants with Severe Eosinophilic Asthma
    Article Snippet: The global legacy benralizumab popPK model, developed using both adult and adolescent data [ ], was refined and validated through a multi-step process, as outlined in Fig. . Population model development and simulation were performed using non-linear, mixed-effects modeling software (NONMEM version 7.5.1; ICON plc, Dublin, Ireland RRID:SCR_016986).

    Article Title: Imputation of missing clock times - application to procalcitonin concentration time course after birth.
    Article Snippet: Data were analysed using non-linear mixed effects models (NONMEM 7.5.1, ICON PLC, Gaithersburg, MA, USA).

    Article Title: Validating Low-Dose Iohexol as a Marker for Glomerular Filtration Rate by In Vitro and In Vivo Studies.
    Article Snippet: A population PK model of iohexol was developed using the nonlinear mixed- effects modeling program NONMEM version 7.5.0 (ICON plc, Dublin, Ireland), Perl speaks NONMEM (PsN) version 5.2.6 (Uppsala University, Uppsala, Sweden) [31], and Pirana version 3.0.0 (Certara, Princeton, New Jersey).

    Article Title: Model-informed dose optimization of mycophenolic acid in pediatric kidney transplant patients.
    Article Snippet: PK model-building and model-evaluation analyses were performed with the software package NONMEM version 7.4.1 (ICON plc, Dublin, Ireland) using the model development dataset.

    Article Title: Population Pharmacokinetics and Exposure-Response Analysis of Benralizumab in Chinese Adults, Adolescents, and Pediatric Participants with Severe Eosinophilic Asthma.
    Article Snippet: Population model development and simulation were performed using non-linear, mixed-effects modeling software (NONMEM version 7.5.1; ICON plc, Dublin, Ireland RRID:SCR_016986).

    Article Title: Toward Model-Informed Precision Dosing for Remimazolam: A Population Pharmacokinetic–Pharmacodynamic Analysis
    Article Snippet: A nonlinear, mixed-effect modeling program (NONMEM, version 7.5, ICON plc, Ellicott City, MD, USA) was used to develop the population PK/PD model. First-order conditional estimation with η-ε interaction method (FOCE-I) was used throughout the model development.

    Article Title: Effect of Cumulative Exposure on the Efficacy of Paroxetine: A Population Pharmacokinetic-Pharmacodynamic and Machine Learning Analyses.
    Article Snippet: Population- based modeling was conducted using a nonlinear mixed- effects model approach in NONMEM (version 7.5.1; ICON plc, Dublin, Ireland) with the first- order conditional estimation with interaction method.



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