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nonlinear mixed effects modelling software nonmem 7.5  (ICON Clinical Research)

 
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    ICON Clinical Research nonlinear mixed effects modelling software nonmem 7.5
    Nonlinear Mixed Effects Modelling Software Nonmem 7.5, supplied by ICON Clinical Research, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nonlinear+mixed-effect+modeling+methods/nonlinear+mixed+effects+modeling+software+nonmem/pmc12141017-134-17-10
    Average 90 stars, based on 1 article reviews
    nonlinear mixed effects modelling software nonmem 7.5 - by Bioz Stars, 2026-10
    90/100 stars

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    other:

    Article Title: A Repeated Time-to-Positive Symptoms Improvement among Malaysian Patients with Schizophrenia Spectrum Disorders Treated with Clozapine
    Article Snippet: The model structure and its parameters were estimated using the Laplace estimation method through the nonlinear mixed-effect modeling software, NONMEM 7.3.0, (ICON Clinical Research LLC, Ellicott City, MD, USA) [ ].

    Article Title: Predicting Antibiotic Effect of Vancomycin Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation: Dense Sampling versus Sparse Sampling
    Article Snippet: Each dataset was estimated using a first-order conditional estimation with an interaction method in a nonlinear mixed-effects modeling software (NONMEM ® 7.5, ICON Clinical Research LLC, North Wales, PA, USA).

    Article Title: Population pharmacokinetics of oral fosfomycin calcium in healthy women
    Article Snippet: Twenty-four healthy women were included in the study, and plasma samples were collected at different times over a period of 24 h. The concentration–time data of fosfomycin in plasma were modelled by a population approach using a nonlinear mixed-effects modelling implemented by NONMEM 7.4 (ICON Clinical Research LLC, North Wales, PA, USA).

    Article Title: Population Pharmacokinetics and Monte Carlo Simulation of Cefepime in Critically Ill Patients with Hospital-Acquired/Ventilator-Associated Pneumonia
    Article Snippet: Population PK analysis was conducted using nonlinear mixed-effects modeling software (version 7.5, NONMEM®, ICON Clinical Research LLC, North Wales, PA, USA).

    Article Title: Population pharmacokinetic analysis of intravenous voriconazole in cancer patients.
    Article Snippet: The population pharmacokinetic (popPK) modeling process was initiated with the Non-Linear Mixed Effect Modeling (NONMEM) software, version 7.4.4 (Icon Clinical Research LLC, New York, USA) which is supported by the PsN toolkit.

    Article Title: Comparative pharmacokinetics of valproic acid among Pakistani and South Korean patients: A population pharmacokinetic study
    Article Snippet: The actual process of popPK modelling was started by using Non-Linear Mixed Effect Modelling NONMEM® software version 7.4.4 (provided by Icon clinical research LLC New York, USA) with the aid of PsN toolkit [ ].

    Software:

    Article Title: Pharmacokinetic and pharmacodynamic analyses of nafamostat in ECMO patients: comparing central vein and ECMO machine samples
    Article Snippet: .. Nonlinear mixed effects modelling software (NONMEM ® , version 7.5, ICON Clinical Research LLC, North Wales, PA, United States) was used for population PK/PD analysis. ..



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    Vancomycin PPK model studies in adult patients by the nonlinear mixed-effects modeling method.

    Journal: Scientific Reports

    Article Title: Population pharmacokinetic modeling and clinical application of vancomycin in Chinese patients hospitalized in intensive care units

    doi: 10.1038/s41598-021-82312-2

    Figure Lengend Snippet: Vancomycin PPK model studies in adult patients by the nonlinear mixed-effects modeling method.

    Article Snippet: Population pharmacokinetic analysis was performed with 993 serum concentrations versus time from 374 adult patients (294 for model building and 80 for external validation, randomly selected by Kinetica), using a nonlinear mixed-effects modeling method with Kinetica.

    Techniques: