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ICON Clinical Research nonlinear mixed-effects modeling software nonmem
Nonlinear Mixed Effects Modeling Software Nonmem, supplied by ICON Clinical Research, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nonlinear+mixed-+effect+modeling+software/nonlinear+mixed+effects+modeling+software+nonmem/pmc10079447-71-7-13
Average 90 stars, based on 1 article reviews
nonlinear mixed-effects modeling software nonmem - by Bioz Stars, 2026-11
90/100 stars

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Article Title: A Repeated Time-to-Positive Symptoms Improvement among Malaysian Patients with Schizophrenia Spectrum Disorders Treated with Clozapine
Article Snippet: The model structure and its parameters were estimated using the Laplace estimation method through the nonlinear mixed-effect modeling software, NONMEM 7.3.0, (ICON Clinical Research LLC, Ellicott City, MD, USA) [ ].

Article Title: Predicting Antibiotic Effect of Vancomycin Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation: Dense Sampling versus Sparse Sampling
Article Snippet: Each dataset was estimated using a first-order conditional estimation with an interaction method in a nonlinear mixed-effects modeling software (NONMEM ® 7.5, ICON Clinical Research LLC, North Wales, PA, USA).

Article Title: Population pharmacokinetics of oral fosfomycin calcium in healthy women
Article Snippet: Twenty-four healthy women were included in the study, and plasma samples were collected at different times over a period of 24 h. The concentration–time data of fosfomycin in plasma were modelled by a population approach using a nonlinear mixed-effects modelling implemented by NONMEM 7.4 (ICON Clinical Research LLC, North Wales, PA, USA).

Article Title: Population Pharmacokinetics and Monte Carlo Simulation of Cefepime in Critically Ill Patients with Hospital-Acquired/Ventilator-Associated Pneumonia
Article Snippet: Population PK analysis was conducted using nonlinear mixed-effects modeling software (version 7.5, NONMEM, ICON Clinical Research LLC, North Wales, PA, USA).

Article Title: Population pharmacokinetic analysis of intravenous voriconazole in cancer patients.
Article Snippet: The population pharmacokinetic (popPK) modeling process was initiated with the Non-Linear Mixed Effect Modeling (NONMEM) software, version 7.4.4 (Icon Clinical Research LLC, New York, USA) which is supported by the PsN toolkit.

Article Title: Comparative pharmacokinetics of valproic acid among Pakistani and South Korean patients: A population pharmacokinetic study
Article Snippet: The actual process of popPK modelling was started by using Non-Linear Mixed Effect Modelling NONMEM® software version 7.4.4 (provided by Icon clinical research LLC New York, USA) with the aid of PsN toolkit [ ].

Software:

Article Title: Pharmacokinetic and pharmacodynamic analyses of nafamostat in ECMO patients: comparing central vein and ECMO machine samples
Article Snippet: .. Nonlinear mixed effects modelling software (NONMEM ® , version 7.5, ICON Clinical Research LLC, North Wales, PA, United States) was used for population PK/PD analysis. ..



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