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nextseq 550 dx platform  (Illumina Inc)


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    Structured Review

    Illumina Inc nextseq 550 dx platform
    Nextseq 550 Dx Platform, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 96/100, based on 407 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nextseq/NextSeq+550+Dx+Sequencing+System/pm35769916-54-6-5
    Average 96 stars, based on 407 article reviews
    nextseq 550 dx platform - by Bioz Stars, 2026-09
    96/100 stars

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    Related Articles

    Next-Generation Sequencing:

    Article Title: Germline BRCA testing in routine clinical practice: a single-center experience.
    Article Snippet: Sequencing-ready libraries were quality-control checked by Tape Station 4,200 instrument using D5000 ScreenTape (Agilent Technologies USA). .. NGS was carried out on a NextSeq 550DX sequencing system with NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles) chemistry (Illumina, Inc. United States) or Multiplicom amplicon-based enrichment BRCA MASTR Dx or BRCA MASTR Plus Dx library preparation kit (Agilent Technologies, Santa Clara, CA) and sequenced on the MiSeq Illumina platform (Illumina, San Diego, CA). .. Bioinformatics analysis was done with the MASTR Reporter software v.1.1 (Agilent Technologies) and by custom bioinformatic analysis pipeline validated to detect single nucleotid variants (SNV) and small insertion/deletion mutations (<40bp)*.

    Article Title: Myoepithelial tumor with EWSR1-PBX3 fusion and rearrangement in rib and soft tissue: a rare case report
    Article Snippet: .. To refine the diagnosis and explore potential therapeutic targets, DNA-based targeted next-generation sequencing (NGS) was performed using the Illumina NextSeq 550Dx platform with a panel (Genecast Biotechnology Co., Ltd.) covering 769 cancer-related genes. ..

    Sequencing:

    Article Title: Germline BRCA testing in routine clinical practice: a single-center experience.
    Article Snippet: Sequencing-ready libraries were quality-control checked by Tape Station 4,200 instrument using D5000 ScreenTape (Agilent Technologies USA). .. NGS was carried out on a NextSeq 550DX sequencing system with NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles) chemistry (Illumina, Inc. United States) or Multiplicom amplicon-based enrichment BRCA MASTR Dx or BRCA MASTR Plus Dx library preparation kit (Agilent Technologies, Santa Clara, CA) and sequenced on the MiSeq Illumina platform (Illumina, San Diego, CA). .. Bioinformatics analysis was done with the MASTR Reporter software v.1.1 (Agilent Technologies) and by custom bioinformatic analysis pipeline validated to detect single nucleotid variants (SNV) and small insertion/deletion mutations (<40bp)*.

    Article Title: High-Grade Astrocytoma With Piloid Features: An Aggressive Clinicogenomic Entity Distinct From Pilocytic Astrocytoma
    Article Snippet: .. Libraries preparation using the SureSelect XT HS and XT Low Input Target Enrichment System (Agilent Technologies, Santa Clara, CA, USA) and sequencing on an Illumina NextSeq 550Dx platform. ..

    Article Title: High-Grade Astrocytoma With Piloid Features: An Aggressive Clinicogenomic Entity Distinct From Pilocytic Astrocytoma.
    Article Snippet: .. Libraries preparation using the SureSelect XT HS and XT Low Input Target Enrichment System (Agilent Technologies, Santa Clara, CA, USA) and sequencing on an Illumina NextSeq 550Dx platform. ..

    Article Title: Distribution and prognostic impact of LymphGen subtypes in Korean diffuse large B-cell lymphoma using clinical NGS panel
    Article Snippet: DNA quality and quantity were assessed with the 4200 TapeStation System (Agilent Technologies). .. Paired-end sequencing was conducted on the Illumina NextSeq 550Dx Platform (Illumina Inc, San Diego, CA). .. Sequencing quality control (QC) metrics were calculated using Picard (Broad Institute, Picard toolkit, 2019; GitHub repository: https://broadinstitute.github.io/picard/ ), SAMtools, and CNVkit, following the framework described by Dreval et al. Metrics included total and aligned read counts, on-target rate, unique alignment rate, corrected mean on-target depth, percentage of targets ≥30× coverage, percentage of 0× targets, and Fold-80 base penalty as well as AT and GC dropout ( and ).

    Article Title: Clinical impact of metagenomic next-generation sequencing on pathogen detection and outcomes in non-immunocompromised patients with severe pneumonia supported by veno-venous extracorporeal membrane oxygenation.
    Article Snippet: .. The qualified single-stranded circular DNA library underwent sequencing on the NextSeq 550Dx platform (Illumina, San Diego, USA) using a single-end 75bp sequencing strategy. ..

    Amplification:

    Article Title: Germline BRCA testing in routine clinical practice: a single-center experience.
    Article Snippet: Sequencing-ready libraries were quality-control checked by Tape Station 4,200 instrument using D5000 ScreenTape (Agilent Technologies USA). .. NGS was carried out on a NextSeq 550DX sequencing system with NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles) chemistry (Illumina, Inc. United States) or Multiplicom amplicon-based enrichment BRCA MASTR Dx or BRCA MASTR Plus Dx library preparation kit (Agilent Technologies, Santa Clara, CA) and sequenced on the MiSeq Illumina platform (Illumina, San Diego, CA). .. Bioinformatics analysis was done with the MASTR Reporter software v.1.1 (Agilent Technologies) and by custom bioinformatic analysis pipeline validated to detect single nucleotid variants (SNV) and small insertion/deletion mutations (<40bp)*.

    Biomarker Discovery:

    Article Title: Myoepithelial tumor with EWSR1-PBX3 fusion and rearrangement in rib and soft tissue: a rare case report
    Article Snippet: .. To refine the diagnosis and explore potential therapeutic targets, DNA-based targeted next-generation sequencing (NGS) was performed using the Illumina NextSeq 550Dx platform with a panel (Genecast Biotechnology Co., Ltd.) covering 769 cancer-related genes. ..



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