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Interactive Biosoftware alamut mutation-interpretation software
Alamut Mutation Interpretation Software, supplied by Interactive Biosoftware, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mutation+interpretation+software/alamut+mutation+interpretation+software/pm37175987-299-29-34
Average 90 stars, based on 1 article reviews
alamut mutation-interpretation software - by Bioz Stars, 2026-09
90/100 stars

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Mutagenesis:

Article Title: Insights into the FOXE3 Transcriptional Network and Disease Mechanisms from the Investigation of a Regulatory Variant Driving Complex Microphthalmia
Article Snippet: .. The pathogenicity of the selected variants was assessed using the Alamut Mutation Interpretation Software ( http://www.interactive-biosoftware.com ), a decision support system for mutation interpretation based on Align DGVD, MutationTaster, PolyPhen-2, SIFT, SpliceSiteFinder-like, MaxEntScan, NNSPLICE, GeneSplicer, Human Splicing Finder, ESEfinder, and RESCUE-ESE. ..

Article Title: Autosomal recessive pathogenic MSTO1 variants in hereditary optic atrophy
Article Snippet: .. The pathogenicity of the selected variants was assessed using the Alamut Mutation Interpretation Software ( http://www.interactive-biosoftware.com ), a decision support system for mutation interpretation based on Align DGVD, MutationTaster, PolyPhen‐2, SIFT, SpliceSiteFinder‐like, MaxEntScan, NNSPLICE, GeneSplicer, Human Splicing Finder, ESEfinder, and RESCUE‐ESE. ..

Article Title: Autosomal recessive pathogenic MSTO1 variants in hereditary optic atrophy.
Article Snippet: .. The pathogenicity of the selected variants was assessed using the Alamut Mutation Interpretation Software (http://www. interactive-biosoftware.com), a decision support system for mutation interpretation based on Align DGVD, MutationTaster, PolyPhen-2, SIFT, SpliceSiteFinder-like, MaxEntScan, NNSPLICE, GeneSplicer, Human Splicing Finder, ESEfinder, and RESCUE-ESE. ..

Article Title: Identification of a novel mutation in the HACD1 gene in an Iranian family with autosomal recessive congenital myopathy, with fibre-type disproportion
Article Snippet: Congenital fibre-type disproportion (CFTD) with myopathy, is a genetically heterogeneous disease in which there is relative hypotrophy of type-1-muscle-fibres compared to type-2-fibres on skeletal muscle biopsy.. The classical characteristics of CFTD are infantile hypotonia and nonprogressive muscle weakness with a broad range of clinical manifestations.. Pathogenic mutations in the HACD1 gene encoding 3-hydroxyacyl-CoA-dehydratase-1 have recently been reported to be associated with this disease.

Article Title: Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication
Article Snippet: .. Alamut mutation interpretation software (Interactive Biosoftware, Rouen, France) 32. ..

Article Title: Beyond Val30Met transthyretin (TTR): variants associated with age-at-onset in hereditary ATTRv amyloidosis.
Article Snippet: All statistical analyses were performed using IBM SPSS Statistics software (v.24). .. To predict the impact of sequence variants on TTR function, bioinformatics tools included in the Alamut Mutation Interpretation Software (Interactive Biosoftware, Rouen France) and Polyphen-2 were applied. ..

Software:

Article Title: Insights into the FOXE3 Transcriptional Network and Disease Mechanisms from the Investigation of a Regulatory Variant Driving Complex Microphthalmia
Article Snippet: .. The pathogenicity of the selected variants was assessed using the Alamut Mutation Interpretation Software ( http://www.interactive-biosoftware.com ), a decision support system for mutation interpretation based on Align DGVD, MutationTaster, PolyPhen-2, SIFT, SpliceSiteFinder-like, MaxEntScan, NNSPLICE, GeneSplicer, Human Splicing Finder, ESEfinder, and RESCUE-ESE. ..

Article Title: Autosomal recessive pathogenic MSTO1 variants in hereditary optic atrophy
Article Snippet: .. The pathogenicity of the selected variants was assessed using the Alamut Mutation Interpretation Software ( http://www.interactive-biosoftware.com ), a decision support system for mutation interpretation based on Align DGVD, MutationTaster, PolyPhen‐2, SIFT, SpliceSiteFinder‐like, MaxEntScan, NNSPLICE, GeneSplicer, Human Splicing Finder, ESEfinder, and RESCUE‐ESE. ..

Article Title: Autosomal recessive pathogenic MSTO1 variants in hereditary optic atrophy.
Article Snippet: .. The pathogenicity of the selected variants was assessed using the Alamut Mutation Interpretation Software (http://www. interactive-biosoftware.com), a decision support system for mutation interpretation based on Align DGVD, MutationTaster, PolyPhen-2, SIFT, SpliceSiteFinder-like, MaxEntScan, NNSPLICE, GeneSplicer, Human Splicing Finder, ESEfinder, and RESCUE-ESE. ..

Article Title: Identification of a novel mutation in the HACD1 gene in an Iranian family with autosomal recessive congenital myopathy, with fibre-type disproportion
Article Snippet: Congenital fibre-type disproportion (CFTD) with myopathy, is a genetically heterogeneous disease in which there is relative hypotrophy of type-1-muscle-fibres compared to type-2-fibres on skeletal muscle biopsy.. The classical characteristics of CFTD are infantile hypotonia and nonprogressive muscle weakness with a broad range of clinical manifestations.. Pathogenic mutations in the HACD1 gene encoding 3-hydroxyacyl-CoA-dehydratase-1 have recently been reported to be associated with this disease.

Article Title: Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication
Article Snippet: .. Alamut mutation interpretation software (Interactive Biosoftware, Rouen, France) 32. ..

Article Title: Beyond Val30Met transthyretin (TTR): variants associated with age-at-onset in hereditary ATTRv amyloidosis.
Article Snippet: All statistical analyses were performed using IBM SPSS Statistics software (v.24). .. To predict the impact of sequence variants on TTR function, bioinformatics tools included in the Alamut Mutation Interpretation Software (Interactive Biosoftware, Rouen France) and Polyphen-2 were applied. ..

other:

Article Title: Genetic Profiling of Sodium Channels in Diabetic Painful and Painless and Idiopathic Painful and Painless Neuropathies
Article Snippet: Variants detected were annotated according to the guidelines of the Human Genome Variation Society ( http://www.hgvs.org/varnomen/ (accessed on 13 April 2015)), and classified according to current classification guidelines [ ] using Alamut Mutation-Interpretation Software (version 2.11, Interactive-Biosoftware, Rouen, France).

Article Title: Genetic Profiling of Sodium Channels in Diabetic Painful and Painless and Idiopathic Painful and Painless Neuropathies.
Article Snippet: Variants detected were annotated according to the guidelines of the Human Genome Variation Society (http://www.hgvs.org/varnomen/ (accessed on 13 April 2015)), and classified according to current classification guidelines [16] using Alamut Mutation-Interpretation Software (version 2.11, Interactive-Biosoftware, Rouen, France).

Variant Assay:

Article Title: Identification of a novel mutation in the HACD1 gene in an Iranian family with autosomal recessive congenital myopathy, with fibre-type disproportion
Article Snippet: Congenital fibre-type disproportion (CFTD) with myopathy, is a genetically heterogeneous disease in which there is relative hypotrophy of type-1-muscle-fibres compared to type-2-fibres on skeletal muscle biopsy.. The classical characteristics of CFTD are infantile hypotonia and nonprogressive muscle weakness with a broad range of clinical manifestations.. Pathogenic mutations in the HACD1 gene encoding 3-hydroxyacyl-CoA-dehydratase-1 have recently been reported to be associated with this disease.

Sequencing:

Article Title: Beyond Val30Met transthyretin (TTR): variants associated with age-at-onset in hereditary ATTRv amyloidosis.
Article Snippet: All statistical analyses were performed using IBM SPSS Statistics software (v.24). .. To predict the impact of sequence variants on TTR function, bioinformatics tools included in the Alamut Mutation Interpretation Software (Interactive Biosoftware, Rouen France) and Polyphen-2 were applied. ..



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