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Arraystar inc mouse circrna array (8 × 15 k)

HFD-modulated gut microbiota regulates the expression of circRNAs. A, The <t>circRNA</t> expression profiles of intestinal tumors from CTL, HFD, and HFD+Abx AOM/DSS model mice were compared via high-throughput circRNA microarray sequencing. B, Mmu_circ_017841, mmu_circ_006689, mmu_circ_32011, circ_38945, mmu_circ_19191, mmu_circ_41893, and mmu_circ_45525, which appeared simultaneously in the upregulated circRNAs of the HFD vs. CTL and HFD+Abx groups. C–E , RT-qPCR was used to verify the differential expression of target mmu_circRNAs (mmu_circ_38945, mmu_circ_32011, mmu_circ_19191, and mmu_circ_45525) in groups of mice generated via three different modeling methods. F, Sanger sequencing results for circ_38945 and circ_0126925. G, Divergent and convergent primers were used to amplify circ_0126925, gDNA, and cDNA with or without RNase treatment before RT-qPCR. H, FISH analysis of the subcellular localization of circ_0126925. I, The proportions of cells in which circ_0126925 was expressed in the nucleus and cytoplasm. J and K, RT-qPCR and ISH were used to detect the expression of circ_0126925 in cancer and adjacent tissues. L, KM curve of the overall survival rate of patients with different expression levels of circ_0126925. In C–E , J , and K , unpaired and paired t tests were used for statistical analyses. In K , the differences between the KM curves were tested for significance by the log-rank test. *, P < 0.05; **, P < 0.01; ***, P < 0.001. ns indicates no significant difference between the two indicated groups.

Mouse Circrna Array (8 × 15 K), supplied by Arraystar inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+circrna+array/mouse+lncrna+microarray+v3+0/pmc11873731-75-8-16
Average 90 stars, based on 1 article reviews

mouse circrna array (8 × 15 k) - by Bioz Stars, 2026-09

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1) Product Images from "Gut Microbiota–Mediated hsa_circ_0126925 Targets BCAA Metabolic Enzyme BCAT2 to Exacerbate Colorectal Cancer Progression"

Article Title: Gut Microbiota–Mediated hsa_circ_0126925 Targets BCAA Metabolic Enzyme BCAT2 to Exacerbate Colorectal Cancer Progression

Journal: Molecular Cancer Research

doi: 10.1158/1541-7786.MCR-24-0434

HFD-modulated gut microbiota regulates the expression of circRNAs. A, The circRNA expression profiles of intestinal tumors from CTL, HFD, and HFD+Abx AOM/DSS model mice were compared via high-throughput circRNA microarray sequencing. B, Mmu_circ_017841, mmu_circ_006689, mmu_circ_32011, circ_38945, mmu_circ_19191, mmu_circ_41893, and mmu_circ_45525, which appeared simultaneously in the upregulated circRNAs of the HFD vs. CTL and HFD+Abx groups. C–E , RT-qPCR was used to verify the differential expression of target mmu_circRNAs (mmu_circ_38945, mmu_circ_32011, mmu_circ_19191, and mmu_circ_45525) in groups of mice generated via three different modeling methods. F, Sanger sequencing results for circ_38945 and circ_0126925. G, Divergent and convergent primers were used to amplify circ_0126925, gDNA, and cDNA with or without RNase treatment before RT-qPCR. H, FISH analysis of the subcellular localization of circ_0126925. I, The proportions of cells in which circ_0126925 was expressed in the nucleus and cytoplasm. J and K, RT-qPCR and ISH were used to detect the expression of circ_0126925 in cancer and adjacent tissues. L, KM curve of the overall survival rate of patients with different expression levels of circ_0126925. In C–E , J , and K , unpaired and paired t tests were used for statistical analyses. In K , the differences between the KM curves were tested for significance by the log-rank test. *, P < 0.05; **, P < 0.01; ***, P < 0.001. ns indicates no significant difference between the two indicated groups.

Figure Legend Snippet: HFD-modulated gut microbiota regulates the expression of circRNAs. A, The circRNA expression profiles of intestinal tumors from CTL, HFD, and HFD+Abx AOM/DSS model mice were compared via high-throughput circRNA microarray sequencing. B, Mmu_circ_017841, mmu_circ_006689, mmu_circ_32011, circ_38945, mmu_circ_19191, mmu_circ_41893, and mmu_circ_45525, which appeared simultaneously in the upregulated circRNAs of the HFD vs. CTL and HFD+Abx groups. C–E , RT-qPCR was used to verify the differential expression of target mmu_circRNAs (mmu_circ_38945, mmu_circ_32011, mmu_circ_19191, and mmu_circ_45525) in groups of mice generated via three different modeling methods. F, Sanger sequencing results for circ_38945 and circ_0126925. G, Divergent and convergent primers were used to amplify circ_0126925, gDNA, and cDNA with or without RNase treatment before RT-qPCR. H, FISH analysis of the subcellular localization of circ_0126925. I, The proportions of cells in which circ_0126925 was expressed in the nucleus and cytoplasm. J and K, RT-qPCR and ISH were used to detect the expression of circ_0126925 in cancer and adjacent tissues. L, KM curve of the overall survival rate of patients with different expression levels of circ_0126925. In C–E , J , and K , unpaired and paired t tests were used for statistical analyses. In K , the differences between the KM curves were tested for significance by the log-rank test. *, P < 0.05; **, P < 0.01; ***, P < 0.001. ns indicates no significant difference between the two indicated groups.

Techniques Used: Expressing, High Throughput Screening Assay, Microarray, Sequencing, Quantitative RT-PCR, Quantitative Proteomics, Generated

other:

Article Title: Genetic inactivation of the Translin/Trax RNase activity alters small RNAs including miRNAs, disrupts gene expression and impairs distinct forms of hippocampal synaptic plasticity and memory
Article Snippet: The Arraystar Mouse Small RNA Array V1.0 comprises a total of 14,192 distinct probes and includes the following coverage for different small RNA species: miRNAs – 1,949 (966 5-p and 983 3-p); pre-miRNAs – 1,122; tsRNAs – 1,767; mature tRNAs – 270; snoRNAs – 1,324.

Article Title: Targeting Ischemic Myocardium: Nanoparticles Loaded with Long Noncoding RNA AK156373 siRNA Alleviate Myocardial Infarction.
Article Snippet: Despite advancements in the development of targeted approaches for the treatment of myocardial infarction (MI), there is a continuing need for improvements in treatment approaches due to the high mortality and prevalence of MI.. The identification of specific therapeutic targets and the development of efficient delivery systems are essential.. In this study, a nanoparticle delivery system targeting necrotic cardiomyocytes was engineered.

Article Title: Gut Microbiota–Mediated hsa_circ_0126925 Targets BCAA Metabolic Enzyme BCAT2 to Exacerbate Colorectal Cancer Progression
Article Snippet: Then, the labeled circRNA was hybridized onto an Arraystar Mouse circRNA Array (8 × 15 K, Arraystar) and incubated in an Agilent Hybridization Incubator (Agilent) at 65°C for 17 hours.

Article Title: Long Non-Coding RNA Osr2 Promotes Fusarium solani Keratitis Inflammation via the miR-30a-3p/ Xcr1 Axis.
Article Snippet: Subsequently, each RNA sample was amplified and transcribed into fluorescent complementary RNA (cRNA), which was then hybridized to the Arraystar Mouse LncRNA Microarray version 4.0.

Article Title: Exploring Mechanisms of Ephx2 in Treating Atherosclerosis Using Independent Cascade Model and Adverse Outcome Pathways.
Article Snippet: Background: Atherosclerosis (AS) is a leading cause of cardiovascular diseases, characterized by lipid accumulation in arterial walls.. The enzyme Ephx2 (soluble epoxide hydrolase, sEH) is implicated in AS development, but its precise mechanisms and therapeutic potential are not fully understood.. Objectives: This study aimed to analyze gene expression data from low-density lipoprotein receptor knockout (LDLR88) and LDLR88sEH88 mice to identify significant genes associated with

Labeling:

Article Title: Circular RNA APP contributes to Alzheimer's disease pathogenesis by modulating microglial polarization via miR-1906/CLIC1 axis.
Article Snippet: Then, the enriched circRNAs were amplified and transcribed into fluorescent cRNA using a random priming method (Arraystar Super RNA Labeling Kit; Arraystar). .. The labeled cRNAs were hybridized onto the Arraystar Mouse circRNA Microarray V2. .. After the slides were washed, the arrays were scanned by the Agilent Scanner G2505C.

Article Title: Characterization of circRNA expression profiles and functional roles in a mouse model of liver injury induced by OSA.
Article Snippet: .. Arraystar Mouse circRNA Array V2 was hybridized with the labeled cRNAs, which were subsequently incubated at 65 °C for 17 h. Following the washing of the slides, we scanned the array using the Agilent Scanner G2505C. .. The resulting array images were analyzed using Agilent Feature Extraction Software.

Microarray:

Incubation:

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Journal: Molecular Cancer Research

Article Title: Gut Microbiota–Mediated hsa_circ_0126925 Targets BCAA Metabolic Enzyme BCAT2 to Exacerbate Colorectal Cancer Progression

doi: 10.1158/1541-7786.MCR-24-0434

Figure Lengend Snippet: HFD-modulated gut microbiota regulates the expression of circRNAs. A, The circRNA expression profiles of intestinal tumors from CTL, HFD, and HFD+Abx AOM/DSS model mice were compared via high-throughput circRNA microarray sequencing. B, Mmu_circ_017841, mmu_circ_006689, mmu_circ_32011, circ_38945, mmu_circ_19191, mmu_circ_41893, and mmu_circ_45525, which appeared simultaneously in the upregulated circRNAs of the HFD vs. CTL and HFD+Abx groups. C–E , RT-qPCR was used to verify the differential expression of target mmu_circRNAs (mmu_circ_38945, mmu_circ_32011, mmu_circ_19191, and mmu_circ_45525) in groups of mice generated via three different modeling methods. F, Sanger sequencing results for circ_38945 and circ_0126925. G, Divergent and convergent primers were used to amplify circ_0126925, gDNA, and cDNA with or without RNase treatment before RT-qPCR. H, FISH analysis of the subcellular localization of circ_0126925. I, The proportions of cells in which circ_0126925 was expressed in the nucleus and cytoplasm. J and K, RT-qPCR and ISH were used to detect the expression of circ_0126925 in cancer and adjacent tissues. L, KM curve of the overall survival rate of patients with different expression levels of circ_0126925. In C–E , J , and K , unpaired and paired t tests were used for statistical analyses. In K , the differences between the KM curves were tested for significance by the log-rank test. *, P < 0.05; **, P < 0.01; ***, P < 0.001. ns indicates no significant difference between the two indicated groups.

Article Snippet: Then, the labeled circRNA was hybridized onto an Arraystar Mouse circRNA Array (8 × 15 K, Arraystar) and incubated in an Agilent Hybridization Incubator (Agilent) at 65°C for 17 hours.

Techniques: Expressing, High Throughput Screening Assay, Microarray, Sequencing, Quantitative RT-PCR, Quantitative Proteomics, Generated

Differentially expressed circRNAs and mRNAs in PGs of db/db mice comparing to db/m mice. ( A ) Volcano plots presenting differences in the expression of circRNAs between db/db and db/m mice. ( B ) Volcano plots presenting differences in the expression of mRNAs between db/db and db/m mice. ( C ) Heat map of top 30 upregulated and downregulated circRNAs with raw intensity higher than 500. ( D ) Heat map of top 30 upregulated and downregulated mRNAs with raw intensity higher than 500. Values plotted on the x- and y-axes represent the averaged normalized signal values of each group (log2-scaled). CircRNA, circular RNA; PGs, parotid glands; mRNA, massage RNA

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: Differentially expressed circRNAs and mRNAs in PGs of db/db mice comparing to db/m mice. ( A ) Volcano plots presenting differences in the expression of circRNAs between db/db and db/m mice. ( B ) Volcano plots presenting differences in the expression of mRNAs between db/db and db/m mice. ( C ) Heat map of top 30 upregulated and downregulated circRNAs with raw intensity higher than 500. ( D ) Heat map of top 30 upregulated and downregulated mRNAs with raw intensity higher than 500. Values plotted on the x- and y-axes represent the averaged normalized signal values of each group (log2-scaled). CircRNA, circular RNA; PGs, parotid glands; mRNA, massage RNA

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques: Expressing

Validation of DE circRNAs and mRNAs by qRT-PCR. ( A ) Expression of 5 selected upregulated circRNAs in db/db mice and db/m mice. ( B ) Expression of 9 selected downregulated circRNAs in db/db mice and db/m mice. ( C ) Expression of 10 selected upregulated mRNAs in db/db mice and db/m mice. ( D ) Expression of 10 selected downregulated mRNAs in db/db mice and db/m mice. * P < 0.05 and ** P < 0.01, versus db/m mice, n = 4. DE, differently expressed; circRNA, circular RNA; mRNA, massage RNA

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: Validation of DE circRNAs and mRNAs by qRT-PCR. ( A ) Expression of 5 selected upregulated circRNAs in db/db mice and db/m mice. ( B ) Expression of 9 selected downregulated circRNAs in db/db mice and db/m mice. ( C ) Expression of 10 selected upregulated mRNAs in db/db mice and db/m mice. ( D ) Expression of 10 selected downregulated mRNAs in db/db mice and db/m mice. * P < 0.05 and ** P < 0.01, versus db/m mice, n = 4. DE, differently expressed; circRNA, circular RNA; mRNA, massage RNA

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques: Quantitative RT-PCR, Expressing

GO and KEGG pathway analysis based on CNC analysis of 7 selected circRNAs. ( A ) GO analysis of co-expressed mRNAs on cellular component (CC), biological process (BP), and molecular function (MF). ( B ) KEGG pathway analysis of co-expressed mRNAs of 7 selected circRNAs. GO, gene ontology; KEGG, kyoto encyclopedia of genes and genomes; CNC, coding–non-coding gene co-expression; mRNA, massage RNA; circRNA, circular RNA

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: GO and KEGG pathway analysis based on CNC analysis of 7 selected circRNAs. ( A ) GO analysis of co-expressed mRNAs on cellular component (CC), biological process (BP), and molecular function (MF). ( B ) KEGG pathway analysis of co-expressed mRNAs of 7 selected circRNAs. GO, gene ontology; KEGG, kyoto encyclopedia of genes and genomes; CNC, coding–non-coding gene co-expression; mRNA, massage RNA; circRNA, circular RNA

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques: Expressing

Coding and non-coding co-expression network involving in PPAR signaling pathway, NF-kappa B signaling pathway, and cytokine-cytokine receptor interaction. Red nodes represent circRNAs; blue nodes represent mRNAs. Positive correlation is a solid line, negative correlation is a dashed line. PPAR, peroxisome proliferator-activated receptor; NF-kappa B, nuclear factor-kappa B; circRNA, circular RNA; mRNA, massage RNA

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: Coding and non-coding co-expression network involving in PPAR signaling pathway, NF-kappa B signaling pathway, and cytokine-cytokine receptor interaction. Red nodes represent circRNAs; blue nodes represent mRNAs. Positive correlation is a solid line, negative correlation is a dashed line. PPAR, peroxisome proliferator-activated receptor; NF-kappa B, nuclear factor-kappa B; circRNA, circular RNA; mRNA, massage RNA

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques: Expressing

GO and KEGG pathway analysis based on ceRNA analysis of 7 selected circRNAs. ( A ) GO analysis of ceRNA function-related mRNAs on cellular component (CC), biological process (BP), and molecular function (MF). ( B ) KEGG pathway analysis of ceRNA function-related mRNAs. GO, gene ontology; KEGG, kyoto encyclopedia of genes and genomes; ceRNA, competing endogenous RNA; circRNA, circular RNA; mRNA, massage RNA

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: GO and KEGG pathway analysis based on ceRNA analysis of 7 selected circRNAs. ( A ) GO analysis of ceRNA function-related mRNAs on cellular component (CC), biological process (BP), and molecular function (MF). ( B ) KEGG pathway analysis of ceRNA function-related mRNAs. GO, gene ontology; KEGG, kyoto encyclopedia of genes and genomes; ceRNA, competing endogenous RNA; circRNA, circular RNA; mRNA, massage RNA

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques:

CircRNA-miRNA-mRNA network involving in the regulation of actin cytoskeleton, leukocyte trans-endothelial migration, and PPAR signaling pathways. Green node represents upregulated circRNAs; yellow nodes represent downregulated circRNAs; red nodes represent miRNAs; blue nodes represent mRNAs. Purple lines with T-shape arrow represent directed relationships; orange lines without arrow represent undirected relationships. CircRNA, circular RNA; miRNA, microRNA; mRNA, massage RNA; PPAR, peroxisome proliferator-activated receptor

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: CircRNA-miRNA-mRNA network involving in the regulation of actin cytoskeleton, leukocyte trans-endothelial migration, and PPAR signaling pathways. Green node represents upregulated circRNAs; yellow nodes represent downregulated circRNAs; red nodes represent miRNAs; blue nodes represent mRNAs. Purple lines with T-shape arrow represent directed relationships; orange lines without arrow represent undirected relationships. CircRNA, circular RNA; miRNA, microRNA; mRNA, massage RNA; PPAR, peroxisome proliferator-activated receptor

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques: Migration

The DE circRNAs, miRNAs, and mRNAs involved in the regulation of actin cytoskeleton signaling pathway

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: The DE circRNAs, miRNAs, and mRNAs involved in the regulation of actin cytoskeleton signaling pathway

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques:

Journal: BMC Genomics

Article Title: Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

doi: 10.1186/s12864-024-10290-6

Figure Lengend Snippet: Primers for validated circRNAs

Article Snippet: The labelled cRNAs were hybridized onto the Arraystar Mouse circRNA Array (8 × 15 K; Arraystar).

Techniques:

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mouse circrna array (8 × 15 k) (Arraystar inc)

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1) Product Images from "Gut Microbiota–Mediated hsa_circ_0126925 Targets BCAA Metabolic Enzyme BCAT2 to Exacerbate Colorectal Cancer Progression"

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