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Genedata Inc morrison ki module
Morrison Ki Module, supplied by Genedata Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/morrison/morrison+ki+module/pm40198752-470-1-5
Average 90 stars, based on 1 article reviews
morrison ki module - by Bioz Stars, 2026-11
90/100 stars

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Article Title: Discovery of Naphthyridinone Derivatives as Selective and Potent PKMYT1 Inhibitors with Antitumor Efficacy.
Article Snippet: PKMYT1 is a crucial regulator of the cell cycle, particularly involved in the G2/M transition through the inhibitory phosphorylation of CDK1, and is a promising therapeutic target for cancer therapy.. Data mining in the Roche kinome screen database identified a hit characterized by 100% PKMYT1 inhibitory activity at a 10 μM concentration, which was further validated with a PKMYT1 enzymatic assay showing double-digit nanomolar potency.. The hit featured a quinolinone central core and a phenol headgroup.



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