microfluidic chip (Dojindo Labs)

Dojindo Labs is a verified supplier

Dojindo Labs manufactures this product

About

News

Press Release

Team

Advisors

Partners

Contact

Bioz Stars

Bioz vStars

Buy from Supplier

Structured Review

Dojindo Labs microfluidic chip

Schematic drawing of a three-dimensional <t>microfluidic</t> glomerulus-on-a-chip device to recapitulate the structure and function of the kidney glomerular filtration barrier. ( A ) Illustration (left panel) and an electron micrograph (right panel) of the glomerular filtration barrier (GFB). The GFB comprises podocytes with their foot processes, glomerular basement membrane, and fenestrated endothelial cells. Foot processes are interconnected by slit diaphragms (arrowheads). ( B ) Architecture of the glomerular chip. The chip consists of three cell culture chambers, four microfluidic channels, and two media reservoirs, in which podocytes (CIHP-1) and glomerular endothelial cells (RFP-HGMVECs) are co-cultured on the collagen type I-coated extracellular matrix of the insert to form the GFB. ( C ) Real image of the microfluidic chip in a cell culture dish (100 mm). ( D ) Workflow for evaluating the integrity and reproducibility of GFB and for developing a glomerulonephritis (GN) model into a microfluidic chip. CIHP-1 cells were first seeded on the bottom surface of a cell culture insert. Then, RFP-HGMVECs were seeded on the inside surface of the insert. Patient serum was added to both the chamber and the inside of the insert on day 8 to induce the GN model.

Microfluidic Chip, supplied by Dojindo Labs, used in various techniques. Bioz Stars score: 99/100, based on 58513 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/miscript+microfluidics+preamp+kit/pmc11121116-237-6-16?v=Dojindo+Labs
Average 99 stars, based on 58513 article reviews

microfluidic chip - by Bioz Stars, 2026-07

99/100 stars

Images

1) Product Images from "Characterizing Glomerular Barrier Dysfunction with Patient-Derived Serum in Glomerulus-on-a-Chip Models: Unveiling New Insights into Glomerulonephritis"

Article Title: Characterizing Glomerular Barrier Dysfunction with Patient-Derived Serum in Glomerulus-on-a-Chip Models: Unveiling New Insights into Glomerulonephritis

Journal: International Journal of Molecular Sciences

doi: 10.3390/ijms25105121

Schematic drawing of a three-dimensional microfluidic glomerulus-on-a-chip device to recapitulate the structure and function of the kidney glomerular filtration barrier. ( A ) Illustration (left panel) and an electron micrograph (right panel) of the glomerular filtration barrier (GFB). The GFB comprises podocytes with their foot processes, glomerular basement membrane, and fenestrated endothelial cells. Foot processes are interconnected by slit diaphragms (arrowheads). ( B ) Architecture of the glomerular chip. The chip consists of three cell culture chambers, four microfluidic channels, and two media reservoirs, in which podocytes (CIHP-1) and glomerular endothelial cells (RFP-HGMVECs) are co-cultured on the collagen type I-coated extracellular matrix of the insert to form the GFB. ( C ) Real image of the microfluidic chip in a cell culture dish (100 mm). ( D ) Workflow for evaluating the integrity and reproducibility of GFB and for developing a glomerulonephritis (GN) model into a microfluidic chip. CIHP-1 cells were first seeded on the bottom surface of a cell culture insert. Then, RFP-HGMVECs were seeded on the inside surface of the insert. Patient serum was added to both the chamber and the inside of the insert on day 8 to induce the GN model.

Figure Legend Snippet: Schematic drawing of a three-dimensional microfluidic glomerulus-on-a-chip device to recapitulate the structure and function of the kidney glomerular filtration barrier. ( A ) Illustration (left panel) and an electron micrograph (right panel) of the glomerular filtration barrier (GFB). The GFB comprises podocytes with their foot processes, glomerular basement membrane, and fenestrated endothelial cells. Foot processes are interconnected by slit diaphragms (arrowheads). ( B ) Architecture of the glomerular chip. The chip consists of three cell culture chambers, four microfluidic channels, and two media reservoirs, in which podocytes (CIHP-1) and glomerular endothelial cells (RFP-HGMVECs) are co-cultured on the collagen type I-coated extracellular matrix of the insert to form the GFB. ( C ) Real image of the microfluidic chip in a cell culture dish (100 mm). ( D ) Workflow for evaluating the integrity and reproducibility of GFB and for developing a glomerulonephritis (GN) model into a microfluidic chip. CIHP-1 cells were first seeded on the bottom surface of a cell culture insert. Then, RFP-HGMVECs were seeded on the inside surface of the insert. Patient serum was added to both the chamber and the inside of the insert on day 8 to induce the GN model.

Techniques Used: Filtration, Membrane, Cell Culture

Review

microfluidic chip (Dojindo Labs)

Structured Review

Images

1) Product Images from "Characterizing Glomerular Barrier Dysfunction with Patient-Derived Serum in Glomerulus-on-a-Chip Models: Unveiling New Insights into Glomerulonephritis"

Similar Products

Image Search Results