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CapitalBio Corporation m. tuberculosis drug resistance gene detection kit
Evaluation and comparison of drug resistance rate of anti- <t> tuberculosis </t> drugs in 2014–2019
M. Tuberculosis Drug Resistance Gene Detection Kit, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray-based+gene+expression+diagnostic+test/drug+resistance+detection+kit/pmc08214299-249-5-17
Average 90 stars, based on 1 article reviews
m. tuberculosis drug resistance gene detection kit - by Bioz Stars, 2026-10
90/100 stars

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1) Product Images from "Prevalence and molecular characteristics of drug-resistant Mycobacterium tuberculosis in Hainan, China: from 2014 to 2019"

Article Title: Prevalence and molecular characteristics of drug-resistant Mycobacterium tuberculosis in Hainan, China: from 2014 to 2019

Journal: BMC Microbiology

doi: 10.1186/s12866-021-02246-7

Evaluation and comparison of drug resistance rate of anti-  tuberculosis  drugs in 2014–2019
Figure Legend Snippet: Evaluation and comparison of drug resistance rate of anti- tuberculosis drugs in 2014–2019

Techniques Used: Comparison

Trends of different drug-resistance patterns among 1484 culture-confirmed TB cases in Hainan, 2014 to 2019. In new cases, for INH resistance (χ 2 = 2.813, P = 0.729); for RIF resistance (χ 2 = 3.181, P = 0.672); for MDR-TB (χ 2 = 4.210, P = 0.520); for XDR-TB (χ 2 = 4.383, P = 0.496). In retreatment cases, for INH resistance (χ 2 = 9.512, P = 0.090); for RIF resistance (χ 2 = 14.257, P = 0.014); for MDR-TB (χ 2 = 10.328, P = 0.066); for XDR-TB (χ 2 = 7.670, P = 0.175). Note: *new cases, **retreatment cases. Abbreviation: INH-R, isoniazid resistance; RIF-R, rifampin resistance; MDR-TB, multidrug resistant tuberculosis; XDR-TB, extensively drug resistant tuberculosis
Figure Legend Snippet: Trends of different drug-resistance patterns among 1484 culture-confirmed TB cases in Hainan, 2014 to 2019. In new cases, for INH resistance (χ 2 = 2.813, P = 0.729); for RIF resistance (χ 2 = 3.181, P = 0.672); for MDR-TB (χ 2 = 4.210, P = 0.520); for XDR-TB (χ 2 = 4.383, P = 0.496). In retreatment cases, for INH resistance (χ 2 = 9.512, P = 0.090); for RIF resistance (χ 2 = 14.257, P = 0.014); for MDR-TB (χ 2 = 10.328, P = 0.066); for XDR-TB (χ 2 = 7.670, P = 0.175). Note: *new cases, **retreatment cases. Abbreviation: INH-R, isoniazid resistance; RIF-R, rifampin resistance; MDR-TB, multidrug resistant tuberculosis; XDR-TB, extensively drug resistant tuberculosis

Techniques Used:

Evolution of drug resistance mutation sites of Mycobacterium  tuberculosis  to first-line anti  tuberculosis  drugs isoniazid and rifampin in 2014–2019
Figure Legend Snippet: Evolution of drug resistance mutation sites of Mycobacterium tuberculosis to first-line anti tuberculosis drugs isoniazid and rifampin in 2014–2019

Techniques Used: Mutagenesis

Related Articles

Diagnostic Assay:

Article Title: Diagnosis of osteoarticular tuberculosis via metagenomic next-generation sequencing: A case report
Article Snippet: .. To verify the mNGS test results, the intra-operative synovial fluid was examined using a variety of validated molecular diagnostic methods for detecting MTB. i) The results of nested PCR targeting the IS6110 gene were positive. ii) PCR and hybridization using the MTB Drug Resistance Detection Array kit (CapitalBio) indicated no rpoB, katG or inhA mutations, indicating that the strain is sensitive to rifampicin and isoniazid. iii) Results of the GeneXpert MTB/RIF test (Cepheid) suggested the presence of MTB and no resistance to rifampin. ..

Nested PCR:

Article Title: Diagnosis of osteoarticular tuberculosis via metagenomic next-generation sequencing: A case report
Article Snippet: .. To verify the mNGS test results, the intra-operative synovial fluid was examined using a variety of validated molecular diagnostic methods for detecting MTB. i) The results of nested PCR targeting the IS6110 gene were positive. ii) PCR and hybridization using the MTB Drug Resistance Detection Array kit (CapitalBio) indicated no rpoB, katG or inhA mutations, indicating that the strain is sensitive to rifampicin and isoniazid. iii) Results of the GeneXpert MTB/RIF test (Cepheid) suggested the presence of MTB and no resistance to rifampin. ..

Polymerase Chain Reaction:

Article Title: Diagnosis of osteoarticular tuberculosis via metagenomic next-generation sequencing: A case report
Article Snippet: .. To verify the mNGS test results, the intra-operative synovial fluid was examined using a variety of validated molecular diagnostic methods for detecting MTB. i) The results of nested PCR targeting the IS6110 gene were positive. ii) PCR and hybridization using the MTB Drug Resistance Detection Array kit (CapitalBio) indicated no rpoB, katG or inhA mutations, indicating that the strain is sensitive to rifampicin and isoniazid. iii) Results of the GeneXpert MTB/RIF test (Cepheid) suggested the presence of MTB and no resistance to rifampin. ..

Hybridization:

Article Title: Diagnosis of osteoarticular tuberculosis via metagenomic next-generation sequencing: A case report
Article Snippet: .. To verify the mNGS test results, the intra-operative synovial fluid was examined using a variety of validated molecular diagnostic methods for detecting MTB. i) The results of nested PCR targeting the IS6110 gene were positive. ii) PCR and hybridization using the MTB Drug Resistance Detection Array kit (CapitalBio) indicated no rpoB, katG or inhA mutations, indicating that the strain is sensitive to rifampicin and isoniazid. iii) Results of the GeneXpert MTB/RIF test (Cepheid) suggested the presence of MTB and no resistance to rifampin. ..

Real-time Polymerase Chain Reaction:

Article Title: Advances in Diagnostic Assays for Tuberculosis
Article Snippet: These include assays launched 20 years ago to assays only recently marketed. table ft1 table-wrap mode="anchored" t5 Table 3. caption a7 Manufacturer (country) Test Market release Fully integrated Dedicated instrument Throughput Detection of drug resistance Intended setting WHO endorsed Regulatory approvals Hologic Genprobe (USA) AMTD test 1993 No Yes 50 tests in 5.5 h No Reference No FDA, CE-IVD Becton Dickinson (USA) BD ProbeTec ET Direct TB Assay 1999 No Yes 150 tests in 8 h No Reference No CE-IVD Hain Lifescience (Germany) GenoType MTBDR plus 2008 No Yes 96 tests per day Yes (MDR) Reference Yes CE-IVD, CFDA Hain Lifescience (Germany) GenoType MTBDR sl 2009 No Yes 96 tests per day Yes (XDR) Reference No CE-IVD Roche (USA) Cobas TaqMan MTB Test 2009 No Yes 44 tests in 3 h No Reference No CE-IVD, Health Canada, FDA? .. Ustar Biotechnologies (China) EasyNAT TB 2009 No No 30 tests per day No Peripheral No CE-IVD CapitalBio (China) Drug Resistance Detection Kit 2009 No Yes 24–48 tests in 8 h Yes (XDR) Reference No CE-IVD, CFDA Cepheid Inc (USA) Xpert MTB/RIF assay 2009 Yes Yes 90 min per cartridge module Yes Intermediate/peripheral Yes CE-IVD, Health Canada, FDA CapitalBio (China) Mycobacteria Real-time PCR 2011 No No 36 tests in 4 h No Reference No CE-IVD, CFDA Seegene (South Korea) Anyplex II MTB/MDR/XDR 2012 No Yes 90 tests in 6 h Yes (XDR) Reference No CE-IVD, Korean FDA Eiken (Japan) Loopamp MTBC Detection Kit 2012 No Yes 14 tests in 2 h No Peripheral No CE-IVD, Japan Epistem (UK) Genedrive Mycobacterium iD Test-kit 2013 No Yes 90 min per test device Yes (MDR) Peripheral No CE-IVD Molbio (India) Truelab TB Assay 2013 No Yes 12 tests in 8 h No Peripheral No CE-IVD, Indian DCGI Tosoh Bioscience (Japan) TRC Rapid M.TB Unknown No Yes N/A No Reference No N/A Open in a separate window Data adapted from UNITAID 2013. ..

other:

Article Title: Diagnostic Performance of GeneChip for the Rapid Detection of Drug-Resistant Tuberculosis in Different Subgroups of Patients
Article Snippet: Fluorescent intensities were quantified by using the M.tb Drug Resistance Detection Array Test System (CapitalBio).

Article Title: Asia emerges as a hotbed of diagnostic innovations for tuberculosis
Article Snippet: CapitalBio M. Tuberculosis Drug Resistance Detection Array Kit , Identifies M. tb complex Detects resistance to rifampicin and isoniazid , CE marking.

Article Title: Prevalence and molecular characteristics of drug-resistant Mycobacterium tuberculosis in Hainan, China: from 2014 to 2019
Article Snippet: This study was based on M. tuberculosis drug resistance gene detection kit (CapitalBioTM DNA microarray method, Beijing CapitalBio Technology, 301,035), which can specifically detect the mutations of rpoB , katG and inhA .

Drug Susceptibility Assay:

Article Title: Hierarchically structured Ag modified nanosilica constructed by micelle modification tactics delivers integrated catalytic and antibacterial activity
Article Snippet: The complexity of environmental pollution poses a severe threat to public health, attracting considerable interest in the search for functional nanomaterials for dye removal and direct disinfection together in wastewater.. Herein, we present a deft synthetic strategy for constructing Ag functionalized hierarchically structured nanosilica (Ag modified mesoporous silica/Ag-ms) using micelle termination incorporating Ag ions as a functional metallomicelle template.. The results showed that multiple active Ag cores were decorated into silica nanospheres.

Staining:

Article Title: Hierarchically structured Ag modified nanosilica constructed by micelle modification tactics delivers integrated catalytic and antibacterial activity
Article Snippet: The complexity of environmental pollution poses a severe threat to public health, attracting considerable interest in the search for functional nanomaterials for dye removal and direct disinfection together in wastewater.. Herein, we present a deft synthetic strategy for constructing Ag functionalized hierarchically structured nanosilica (Ag modified mesoporous silica/Ag-ms) using micelle termination incorporating Ag ions as a functional metallomicelle template.. The results showed that multiple active Ag cores were decorated into silica nanospheres.

Microarray:

Article Title: Hierarchically structured Ag modified nanosilica constructed by micelle modification tactics delivers integrated catalytic and antibacterial activity
Article Snippet: The complexity of environmental pollution poses a severe threat to public health, attracting considerable interest in the search for functional nanomaterials for dye removal and direct disinfection together in wastewater.. Herein, we present a deft synthetic strategy for constructing Ag functionalized hierarchically structured nanosilica (Ag modified mesoporous silica/Ag-ms) using micelle termination incorporating Ag ions as a functional metallomicelle template.. The results showed that multiple active Ag cores were decorated into silica nanospheres.



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