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infinium microarray platform  (INFINIUM Inc)

 
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    INFINIUM Inc infinium microarray platform
    Infinium Microarray Platform, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+expression+and+methylation+probe/infinium+microarray/pm32618141-162-2-1
    Average 90 stars, based on 1 article reviews
    infinium microarray platform - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    other:

    Article Title: Epigenomic signature of accelerated ageing in progeroid Cockayne syndrome
    Article Snippet: Moreover, we may have underestimated the correlation between DNAm and transcription, since our experimental procedures (i.e., the use of Infinium microarray on bisulfite‐treated DNA), like the published databases that we used for comparisons, do not distinguish DNA methylation from DNA hydroxymethylation.

    Article Title: The technology landscape for detection of DNA methylation in cancer liquid biopsies
    Article Snippet: The 450K chips are no longer manufactured, but recent studies show identical results with the Infinium EPIC microarrays.

    Article Title: scMD: cell type deconvolution using single-cell DNA methylation references
    Article Snippet: The DNAm data for NAc was profiled using the Infinium MethylationEPIC/850k microarray following the guidelines provided by the manufacturer.

    Article Title: A circulating cell-free DNA methylation signature for the detection of hepatocellular carcinoma
    Article Snippet: The first panel displays the number of normal (N) and HCC (T) methylome data from CGRC and TCGA cohorts obtained using Infinium microarray (top).

    Article Title: Novel DNA methylation changes in mouse lungs associated with chronic smoking
    Article Snippet: Sequentially increasing scales of the Infinium microarrays have been developed for human samples, but no such solution was available for use on mouse samples until recently, with the release of the Illumina Infinium mouse microarrays [ ].

    Article Title: Epigenomic signature of accelerated ageing in progeroid Cockayne syndrome.
    Article Snippet: Moreover, we may have underestimated the correlation between DNAm and transcription, since our experimental procedures (i.e., the use of Infinium microarray on bisulfite- treated DNA), like the published databases that we used for comparisons, do not distinguish DNA methylation from DNA hydroxymethylation.

    Genome Wide:

    Article Title: Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways
    Article Snippet: .. At culture endpoint, cells were harvested for methylome- and genome-wide association analysis using infinium microarray technology. ..

    Microarray:

    Article Title: Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways
    Article Snippet: .. At culture endpoint, cells were harvested for methylome- and genome-wide association analysis using infinium microarray technology. ..

    Article Title: Causal analysis on DNA methylation reveals key regulators in aging and senescence
    Article Snippet: .. Epigenetics data from those samples were generated using an Infinium microarray, a total of 865859 sites. ..

    Generated:

    Article Title: Causal analysis on DNA methylation reveals key regulators in aging and senescence
    Article Snippet: .. Epigenetics data from those samples were generated using an Infinium microarray, a total of 865859 sites. ..



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    We collected published datasets of human blood samples for gene expression, DNA methylation, and single-cell transcriptomic data. The analysis aimed to study the relation between the expression and DNA methylation of retrotransposons (RTEs) versus chronological and biological aging in large human cohorts. The single-cell transcriptomic datasets were employed for cell type-specific analysis of RTEs in peripheral blood mononuclear cell (PBMC) to identify the relation between RTE expression and aging events for annotated cell types within old versus young PBMC samples.

    Journal: eLife

    Article Title: Expression of most retrotransposons in human blood correlates with biological aging

    doi: 10.7554/eLife.96575

    Figure Lengend Snippet: We collected published datasets of human blood samples for gene expression, DNA methylation, and single-cell transcriptomic data. The analysis aimed to study the relation between the expression and DNA methylation of retrotransposons (RTEs) versus chronological and biological aging in large human cohorts. The single-cell transcriptomic datasets were employed for cell type-specific analysis of RTEs in peripheral blood mononuclear cell (PBMC) to identify the relation between RTE expression and aging events for annotated cell types within old versus young PBMC samples.

    Article Snippet: By overlapping Illumina microarray expression and methylation probe locations to RTE locations in RepeatMasker , we were able to identify a sufficient number of probes to calculate the expression and methylation levels of RTE classes and families.

    Techniques: Gene Expression, DNA Methylation Assay, Expressing

    (a, b), Methylation levels of RTE classes inversely correlated with chronological age in monocyte (Multi-Ethnic Study of Atherosclerosis, MESA) and whole blood (WB) (BSGS, SATSA, and GMPWAR) samples. Satellite DNA was included as a control group. ( c ), Methylation levels versus low (first quartile), medium (second and third quartile), and high (fourth quartile) expressions of RTE classes in monocytes (MESA). Wilcoxon test; ns: not significant. ( d ), Correlation matrix for RTE expressions and methylation levels, and chronological age. *p≤0.05, **p≤0.01, ***p≤0.001, ****p≤0.0001, Pearson’s correlation. MESA, n=1202; BSGS, n=614; GMPWAR, n=656; SATSA, n=1072.

    Journal: eLife

    Article Title: Expression of most retrotransposons in human blood correlates with biological aging

    doi: 10.7554/eLife.96575

    Figure Lengend Snippet: (a, b), Methylation levels of RTE classes inversely correlated with chronological age in monocyte (Multi-Ethnic Study of Atherosclerosis, MESA) and whole blood (WB) (BSGS, SATSA, and GMPWAR) samples. Satellite DNA was included as a control group. ( c ), Methylation levels versus low (first quartile), medium (second and third quartile), and high (fourth quartile) expressions of RTE classes in monocytes (MESA). Wilcoxon test; ns: not significant. ( d ), Correlation matrix for RTE expressions and methylation levels, and chronological age. *p≤0.05, **p≤0.01, ***p≤0.001, ****p≤0.0001, Pearson’s correlation. MESA, n=1202; BSGS, n=614; GMPWAR, n=656; SATSA, n=1072.

    Article Snippet: By overlapping Illumina microarray expression and methylation probe locations to RTE locations in RepeatMasker , we were able to identify a sufficient number of probes to calculate the expression and methylation levels of RTE classes and families.

    Techniques: Methylation, Control

    (a, b), Methylation levels of long terminal repeats (LTR) and LINE/SINE families negatively correlate with chronological age in monocytes (MESA) and the WB (BSGS, SATSA, and GMPWAR). **p≤0.01, ***p≤0.001, Wilcoxon test.

    Journal: eLife

    Article Title: Expression of most retrotransposons in human blood correlates with biological aging

    doi: 10.7554/eLife.96575

    Figure Lengend Snippet: (a, b), Methylation levels of long terminal repeats (LTR) and LINE/SINE families negatively correlate with chronological age in monocytes (MESA) and the WB (BSGS, SATSA, and GMPWAR). **p≤0.01, ***p≤0.001, Wilcoxon test.

    Article Snippet: By overlapping Illumina microarray expression and methylation probe locations to RTE locations in RepeatMasker , we were able to identify a sufficient number of probes to calculate the expression and methylation levels of RTE classes and families.

    Techniques: Methylation

    While LINE families, MIR, and long terminal repeats (LTR) families except ERVK show lower levels of methylation in higher expression groups, this pattern is not seen in Alu, CR1, and ERVl. *p≤0.05, **p≤0.01, ***p≤0.001, ****p≤0.0001, ns: not significant, Wilcoxon test.

    Journal: eLife

    Article Title: Expression of most retrotransposons in human blood correlates with biological aging

    doi: 10.7554/eLife.96575

    Figure Lengend Snippet: While LINE families, MIR, and long terminal repeats (LTR) families except ERVK show lower levels of methylation in higher expression groups, this pattern is not seen in Alu, CR1, and ERVl. *p≤0.05, **p≤0.01, ***p≤0.001, ****p≤0.0001, ns: not significant, Wilcoxon test.

    Article Snippet: By overlapping Illumina microarray expression and methylation probe locations to RTE locations in RepeatMasker , we were able to identify a sufficient number of probes to calculate the expression and methylation levels of RTE classes and families.

    Techniques: Methylation, Expressing