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microarray and ngs datasets  (Broad Institute Inc)

 
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    Broad Institute Inc microarray and ngs datasets
    Microarray And Ngs Datasets, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+dataset/microarray+and+ngs+datasets/pmc03580496-74-9-38
    Average 90 stars, based on 1 article reviews
    microarray and ngs datasets - by Bioz Stars, 2026-09
    90/100 stars

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    Microarray:

    Article Title: InSilico DB genomic datasets hub: an efficient starting point for analyzing genome-wide studies in GenePattern, Integrative Genomics Viewer, and R/Bioconductor
    Article Snippet: .. InSilico DB contains a large number of microarray and NGS datasets originating from public repositories, NCBI Gene Expression Omnibus (GEO) [ ], Short Read Archive (SRA) [ ], The Cancer Genome Atlas project (TCGA) [ ] and the Broad Institute [ ]. .. Currently, InSilico DB supports gene expression microarray Affymetrix and Illumina platforms, and Illumina NGS platforms (for an up-to-date list of available platforms, visit [ ]).

    Next-Generation Sequencing:

    Article Title: InSilico DB genomic datasets hub: an efficient starting point for analyzing genome-wide studies in GenePattern, Integrative Genomics Viewer, and R/Bioconductor
    Article Snippet: .. InSilico DB contains a large number of microarray and NGS datasets originating from public repositories, NCBI Gene Expression Omnibus (GEO) [ ], Short Read Archive (SRA) [ ], The Cancer Genome Atlas project (TCGA) [ ] and the Broad Institute [ ]. .. Currently, InSilico DB supports gene expression microarray Affymetrix and Illumina platforms, and Illumina NGS platforms (for an up-to-date list of available platforms, visit [ ]).

    Gene Expression:

    Article Title: InSilico DB genomic datasets hub: an efficient starting point for analyzing genome-wide studies in GenePattern, Integrative Genomics Viewer, and R/Bioconductor
    Article Snippet: .. InSilico DB contains a large number of microarray and NGS datasets originating from public repositories, NCBI Gene Expression Omnibus (GEO) [ ], Short Read Archive (SRA) [ ], The Cancer Genome Atlas project (TCGA) [ ] and the Broad Institute [ ]. .. Currently, InSilico DB supports gene expression microarray Affymetrix and Illumina platforms, and Illumina NGS platforms (for an up-to-date list of available platforms, visit [ ]).



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    Image Search Results


    TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm

    Journal: Journal of Neuroinflammation

    Article Title: TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination

    doi: 10.1186/s12974-026-03769-4

    Figure Lengend Snippet: TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm

    Article Snippet: The microarray dataset GSE138614 was retrieved from the Gene Expression Omnibus (GEO) repository of the National Center for Biotechnology Information ( https://www.ncbi.nlm.nih.gov/geo/ ).

    Techniques: Expressing, Control, Gene Expression, Microarray, Quantitative RT-PCR, Western Blot, Immunofluorescence, Marker

    SIRT3 is downregulated in RCC. ( A ) Based on the GEO GSE53757 dataset, SIRT3 mRNA levels in RCC tissues were compared with those in normal tissues. ( B ) SIRT3 protein levels in RCC tissues were analyzed in comparison to adjacent normal tissues using CPTAC data. ( C ) SIRT3 protein levels in RCC tissues and normal tissues were detected using immunohistochemistry (IHC). A scatter plot was generated to display the expression of SIRT3 in adjacent normal tissues versus RCC tissues. ( D, E ) Enrichment plots were produced to illustrate the gene expression signatures for proliferation (CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN) and migration (GOBP_ENDOTHELIAL_CELL_MIGRATION). *** P < 0.001.

    Journal: Scientific Reports

    Article Title: SIRT3 suppresses renal cancer progression by regulating IDH2 acetylation

    doi: 10.1038/s41598-026-37783-6

    Figure Lengend Snippet: SIRT3 is downregulated in RCC. ( A ) Based on the GEO GSE53757 dataset, SIRT3 mRNA levels in RCC tissues were compared with those in normal tissues. ( B ) SIRT3 protein levels in RCC tissues were analyzed in comparison to adjacent normal tissues using CPTAC data. ( C ) SIRT3 protein levels in RCC tissues and normal tissues were detected using immunohistochemistry (IHC). A scatter plot was generated to display the expression of SIRT3 in adjacent normal tissues versus RCC tissues. ( D, E ) Enrichment plots were produced to illustrate the gene expression signatures for proliferation (CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN) and migration (GOBP_ENDOTHELIAL_CELL_MIGRATION). *** P < 0.001.

    Article Snippet: The GSE53757 microarray dataset was obtained through the National Center for Biotechnology Information Gene Expression Omnibus database (NCBI GEO, https://www.ncbi.nlm.nih.gov/gds/?term=GSE53757 ).

    Techniques: Comparison, Immunohistochemistry, Generated, Expressing, Produced, Gene Expression, Migration