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gene expression data  (MediSapiens Ltd)

 
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    MediSapiens Ltd gene expression data
    Gene Expression Data, supplied by MediSapiens Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+data+analysis+raw+data/microarray+data+analysis/pmc05036535-165-0-10
    Average 90 stars, based on 1 article reviews
    gene expression data - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Expressing:

    Article Title: ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas
    Article Snippet: .. Oncomine box plots of AGR2 and ZEB1 levels in human lung adenocarcinoma and normal lung tissues in three various datasets (Okamaya, Selamat, Landi), Figure S2: Lung cancer patients’ mRNA expression profiling ( n = 1439) to compare AGR2 vs. CDH1 and ZEB1 ( http://ist.medisapiens.com ), Figure S3: Graph for TCGA Lung adenocarcinoma data showing the gene expression of ZEB1 in lung adenocarcinoma patients with respect to AGR2 expression ( http://xena.ucsc.edu ), Figure S4: The AGR2 expression level in primary tumor site and metastasis. ..

    Article Title: Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection.
    Article Snippet: .. Interestingly, publicly available gene expression databases, such as MediSapiens, indicate highest KLHL15 expression levels predominantly in hematopoietic stem cells and in all four main types of leukemia (http://ist.medisapiens.com/#ENSG00000174010). ..


    Article Title: B7-H7 Is Inducible on T Cells to Regulate Their Immune Response and Serves as a Marker for Exhaustion
    Article Snippet: .. While antigen-presenting cells and myeloid cells were reported to be the major cell types that expressed B7-H7, mRNA expression data from IST Medisapiens demonstrated that B7-H7 was expressed on most immune cells at the RNA level, including T cells ( ). ..

    Gene Expression:

    Article Title: ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas
    Article Snippet: .. Oncomine box plots of AGR2 and ZEB1 levels in human lung adenocarcinoma and normal lung tissues in three various datasets (Okamaya, Selamat, Landi), Figure S2: Lung cancer patients’ mRNA expression profiling ( n = 1439) to compare AGR2 vs. CDH1 and ZEB1 ( http://ist.medisapiens.com ), Figure S3: Graph for TCGA Lung adenocarcinoma data showing the gene expression of ZEB1 in lung adenocarcinoma patients with respect to AGR2 expression ( http://xena.ucsc.edu ), Figure S4: The AGR2 expression level in primary tumor site and metastasis. ..

    Article Title: Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection.
    Article Snippet: .. Interestingly, publicly available gene expression databases, such as MediSapiens, indicate highest KLHL15 expression levels predominantly in hematopoietic stem cells and in all four main types of leukemia (http://ist.medisapiens.com/#ENSG00000174010). ..

    Article Title: Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
    Article Snippet: .. 10 Cell Systems 4, 1–15, April 26, 2017 Since the most common mechanism of cancer development is the overexpression of cellular genes, we also extracted and hierarchically clustered the gene expression profiles of these 46 phosphatase-CAP network proteins from 281 different human cancer tissues (IST Online; MediSapiens). ..

    Article Title: THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours.
    Article Snippet: .. E Gene expression profile in the MediSapiens IST Online transcriptome database. ..

    other:

    Article Title: Low infiltration of tumor-associated macrophages in high c-Myb-expressing breast tumors
    Article Snippet: We calculated correlation coefficients for MYB and monocyte/macrophage recruitment factors in three independent datasets (Gene Expression Omnibus, GEO, accession numbers GSE22358, GSE12276, GSE25066) and in Medisapiens meta-base.

    Over Expression:

    Article Title: Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
    Article Snippet: .. 10 Cell Systems 4, 1–15, April 26, 2017 Since the most common mechanism of cancer development is the overexpression of cellular genes, we also extracted and hierarchically clustered the gene expression profiles of these 46 phosphatase-CAP network proteins from 281 different human cancer tissues (IST Online; MediSapiens). ..

    RNA Expression:

    Article Title: PROX1 transcription factor is a master regulator of myogenic and oncogenic features of rhabdomyosarcoma
    Article Snippet: Several such genes were found to be significantly repressed by PROX1 silencing: FGFR4, MYL4 , IGFBP5, IGF2 ( ; ), MYOG , MYCN , RASSF4 , VANGL2 , Hey1 ( ) and NOTCH3 ( ) ( ). .. Correlation analysis of these genes with PROX1 using RMS tumor RNA expression data in MediSapiens (n = 49 tumors, http://ist.medisapiens.com/ ) showed significant correlation between PROX1 and six of these genes , of which one of the strongest correlations was found between PROX1 and FGFR4 ( ). ..



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    Image Search Results


    Microarray analysis using mRNA from p16−/− BMDM compared to p16+/+ BMDM showed (A) decreased mRNA expression of classically activated macrophages-associated genes and (B) increased mRNA expression of alternatively activated macrophages-associated genes. Data is expressed as fold change relative to p16+/+ BMDM. (C) Differential gene expression in p16−/− BMDM relative to p16+/+ BMDM was correlated with the changes induced in IL-4-induced p16+/+ AAMφ. The figure shows 2log values of the probesets significantly (p<0.05) regulated only in p16−/− BMDM (red dots), only in IL-4-polarized p16+/+ AAMφ (green dots) and by both conditions (blue dots), compared to p16+/+ BMDM. The X-axis represents differences in gene expression induced by IL-4, whereas the Y-axis represents the effect of p16INKa-deficiency. These comparisons are depicted in the schematic representation of the protocol in the corresponding colors. Pearson Correlation analysis was done for probesets differentially expressed by both conditions (blue). (D) Heat map of p16+/+ BMDM, p16−/− BMDM, IL-4-polarized p16+/+ and p16−/− AAMφ gene expression profiles. Colors fluctuate from blue (poorly expressed) to green (intermediate expression) and yellow (high expression). Additional information regarding gene description, fold induction, and p-value can be found in Table S3.

    Journal: Blood

    Article Title: p16 INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages

    doi: 10.1182/blood-2010-10-313106

    Figure Lengend Snippet: Microarray analysis using mRNA from p16−/− BMDM compared to p16+/+ BMDM showed (A) decreased mRNA expression of classically activated macrophages-associated genes and (B) increased mRNA expression of alternatively activated macrophages-associated genes. Data is expressed as fold change relative to p16+/+ BMDM. (C) Differential gene expression in p16−/− BMDM relative to p16+/+ BMDM was correlated with the changes induced in IL-4-induced p16+/+ AAMφ. The figure shows 2log values of the probesets significantly (p<0.05) regulated only in p16−/− BMDM (red dots), only in IL-4-polarized p16+/+ AAMφ (green dots) and by both conditions (blue dots), compared to p16+/+ BMDM. The X-axis represents differences in gene expression induced by IL-4, whereas the Y-axis represents the effect of p16INKa-deficiency. These comparisons are depicted in the schematic representation of the protocol in the corresponding colors. Pearson Correlation analysis was done for probesets differentially expressed by both conditions (blue). (D) Heat map of p16+/+ BMDM, p16−/− BMDM, IL-4-polarized p16+/+ and p16−/− AAMφ gene expression profiles. Colors fluctuate from blue (poorly expressed) to green (intermediate expression) and yellow (high expression). Additional information regarding gene description, fold induction, and p-value can be found in Table S3.

    Article Snippet: We thank E. Vallez for mouse breeding, J. Brozek (Genfit SA, Loos, France) for microarray raw data analysis, T. Coevoet, N. Jouy and A. Lucas for technical assistance.

    Techniques: Microarray, Expressing, Gene Expression

    Representation of the relative microarray intensity values from a selection of down-regulated genes in p16+/+ and p16−/− BMDM with or without polarization (AAMφ) by 15 ng/mL IL-4 from day 0 of differentiation. Statistically significant differences are indicated (a: p<0.05 compared to p16+/+ BMDM; b: p<0.05 compared to p16−/− BMDM; c: p<0.05 compared to p16+/+ AAMφ.)

    Journal: Blood

    Article Title: p16 INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages

    doi: 10.1182/blood-2010-10-313106

    Figure Lengend Snippet: Representation of the relative microarray intensity values from a selection of down-regulated genes in p16+/+ and p16−/− BMDM with or without polarization (AAMφ) by 15 ng/mL IL-4 from day 0 of differentiation. Statistically significant differences are indicated (a: p<0.05 compared to p16+/+ BMDM; b: p<0.05 compared to p16−/− BMDM; c: p<0.05 compared to p16+/+ AAMφ.)

    Article Snippet: We thank E. Vallez for mouse breeding, J. Brozek (Genfit SA, Loos, France) for microarray raw data analysis, T. Coevoet, N. Jouy and A. Lucas for technical assistance.

    Techniques: Microarray, Selection

    Validation of DNA Microarray Results by qPCR

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Perimysial Fibroblasts of Extraocular Muscle, as Unique as the Muscle Fibers

    doi: 10.1167/iovs.08-2857

    Figure Lengend Snippet: Validation of DNA Microarray Results by qPCR

    Article Snippet: DNA Microarray Data Analysis Raw data from microarray scans were analyzed with microarray analysis software (GCOS 2.0; Affymetrix).

    Techniques: Biomarker Discovery, Microarray