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INFINIUM Inc dna methylation microarrays 450k
Analysis of a large <t>DNA</t> methylation dataset of blood samples profiled using Infinium <t>450k.</t> a Scatterplot showing the correlation between epigenetic age predicted from DNA methylation and reported chronological age for 729 healthy donors (three individuals were excluded because no chronological age was reported). b Positioning of the samples in two-dimensional space for sex prediction. c Statistical association between principal components (columns) and sample annotations (rows). Significant associations with p values below 0.01 are marked by filled circles, while non-significant values are represented as empty circles. d Principal component analysis for 792 blood-based DNA methylation profiles, comprising 732 peripheral blood samples and 60 sorted blood cell populations, using the same principal components as in panel c . Immune cell content was estimated using the LUMP algorithm. e Scatterplot showing the negative correlation between chronological age and the estimated fraction of CD4 + T cells
Dna Methylation Microarrays 450k, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/methylation+microarray+platform+illumina+27k+array/infinium+humanmethylation450+beadchip/pmc06419383-115-3-2
Average 90 stars, based on 1 article reviews
dna methylation microarrays 450k - by Bioz Stars, 2026-11
90/100 stars

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1) Product Images from "RnBeads 2.0: comprehensive analysis of DNA methylation data"

Article Title: RnBeads 2.0: comprehensive analysis of DNA methylation data

Journal: Genome Biology

doi: 10.1186/s13059-019-1664-9

Analysis of a large DNA methylation dataset of blood samples profiled using Infinium 450k. a Scatterplot showing the correlation between epigenetic age predicted from DNA methylation and reported chronological age for 729 healthy donors (three individuals were excluded because no chronological age was reported). b Positioning of the samples in two-dimensional space for sex prediction. c Statistical association between principal components (columns) and sample annotations (rows). Significant associations with p values below 0.01 are marked by filled circles, while non-significant values are represented as empty circles. d Principal component analysis for 792 blood-based DNA methylation profiles, comprising 732 peripheral blood samples and 60 sorted blood cell populations, using the same principal components as in panel c . Immune cell content was estimated using the LUMP algorithm. e Scatterplot showing the negative correlation between chronological age and the estimated fraction of CD4 + T cells
Figure Legend Snippet: Analysis of a large DNA methylation dataset of blood samples profiled using Infinium 450k. a Scatterplot showing the correlation between epigenetic age predicted from DNA methylation and reported chronological age for 729 healthy donors (three individuals were excluded because no chronological age was reported). b Positioning of the samples in two-dimensional space for sex prediction. c Statistical association between principal components (columns) and sample annotations (rows). Significant associations with p values below 0.01 are marked by filled circles, while non-significant values are represented as empty circles. d Principal component analysis for 792 blood-based DNA methylation profiles, comprising 732 peripheral blood samples and 60 sorted blood cell populations, using the same principal components as in panel c . Immune cell content was estimated using the LUMP algorithm. e Scatterplot showing the negative correlation between chronological age and the estimated fraction of CD4 + T cells

Techniques Used: DNA Methylation Assay

Related Articles

DNA Methylation Assay:

Article Title: Sex differences in resting skeletal muscle and the acute and long-term response to endurance exercise in individuals with overweight and obesity
Article Snippet: The bisulfite treatment and hybridization of the DNA samples were carried out by Life & Brain (Bonn, Germany). .. DNA methylation levels were determined by the Infinium MethylationEPIC BeadChip version 1. ..

Article Title: Convergent DNA Methylation Abnormalities at Bivalent Chromatin in Human Growth Disorders
Article Snippet: .. DNA methylation data from blood of individuals with DNMT3A- or NSD1-associated growth syndromes, generated using the Infinium HumanMethylation450K or EPIC arrays, were obtained from published studies [ ], [ ], [ ] ( Supplemental Table 1). ..

Article Title: Colon cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 450,000 sites generated using the Infinium 450K Methylation Array. ..

Article Title: Supplementary Materials Association between genome-wide epigenetic and genetic alterations in breast cancer tissue and response to HER2-targeted therapies in HER2-positive breast cancer patients: new findings and a systematic review
Article Snippet: .. Summary characteristics of one study of genome-wide DNA methylation measured in breast cancer tissue and risk of recurrence among HER2-positive, trastuzumab- treated breast cancer patients (n = 1) Study design Retrospective study: Furrer [2022] Breast cancer patients Number of patients: 12 Mean age: 51.3 y Postmenopausal patients: 67% ER-positive breast cancer: 67% DNA methylation Measurement method: Infinium HumanMethylation450 BeadChip array Tissue used: FFPE Tumor cell fraction: ≥ 70% Outcome DFS DFS: Disease free survival; ER: estrogen receptor; FFPE: formalin-fixed, paraffin-embedded; n: number of studies; y: years. ..

Article Title: Liver cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 485,000 sites generated using the Infinium 450K Methylation Array. ..

Article Title: Colon cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 27,000 sites generated using the Infinium 450K Methylation Array. ..

Generated:

Article Title: Convergent DNA Methylation Abnormalities at Bivalent Chromatin in Human Growth Disorders
Article Snippet: .. DNA methylation data from blood of individuals with DNMT3A- or NSD1-associated growth syndromes, generated using the Infinium HumanMethylation450K or EPIC arrays, were obtained from published studies [ ], [ ], [ ] ( Supplemental Table 1). ..

Article Title: Colon cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 450,000 sites generated using the Infinium 450K Methylation Array. ..

Article Title: Liver cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 485,000 sites generated using the Infinium 450K Methylation Array. ..

Article Title: Colon cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 27,000 sites generated using the Infinium 450K Methylation Array. ..

Pathology:

Article Title: BRAF V600E maintains the CpG island methylator phenotype, and DNA methylation of PRC2 targets genes in colon cancer
Article Snippet: .. The authors thank the Pathology department at the UMC Utrecht for running the Infinium MethylationEPIC array. ..

Methylation:

Article Title: Colon cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 450,000 sites generated using the Infinium 450K Methylation Array. ..

Article Title: Liver cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 485,000 sites generated using the Infinium 450K Methylation Array. ..

Article Title: Colon cancer methylation markers and uses thereof
Article Snippet: .. DNA methylation data were obtained from the TCGA analysis of about 27,000 sites generated using the Infinium 450K Methylation Array. ..

Genome Wide:

Article Title: Supplementary Materials Association between genome-wide epigenetic and genetic alterations in breast cancer tissue and response to HER2-targeted therapies in HER2-positive breast cancer patients: new findings and a systematic review
Article Snippet: .. Summary characteristics of one study of genome-wide DNA methylation measured in breast cancer tissue and risk of recurrence among HER2-positive, trastuzumab- treated breast cancer patients (n = 1) Study design Retrospective study: Furrer [2022] Breast cancer patients Number of patients: 12 Mean age: 51.3 y Postmenopausal patients: 67% ER-positive breast cancer: 67% DNA methylation Measurement method: Infinium HumanMethylation450 BeadChip array Tissue used: FFPE Tumor cell fraction: ≥ 70% Outcome DFS DFS: Disease free survival; ER: estrogen receptor; FFPE: formalin-fixed, paraffin-embedded; n: number of studies; y: years. ..

Formalin-fixed Paraffin-Embedded:

Article Title: Supplementary Materials Association between genome-wide epigenetic and genetic alterations in breast cancer tissue and response to HER2-targeted therapies in HER2-positive breast cancer patients: new findings and a systematic review
Article Snippet: .. Summary characteristics of one study of genome-wide DNA methylation measured in breast cancer tissue and risk of recurrence among HER2-positive, trastuzumab- treated breast cancer patients (n = 1) Study design Retrospective study: Furrer [2022] Breast cancer patients Number of patients: 12 Mean age: 51.3 y Postmenopausal patients: 67% ER-positive breast cancer: 67% DNA methylation Measurement method: Infinium HumanMethylation450 BeadChip array Tissue used: FFPE Tumor cell fraction: ≥ 70% Outcome DFS DFS: Disease free survival; ER: estrogen receptor; FFPE: formalin-fixed, paraffin-embedded; n: number of studies; y: years. ..



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