Journal: Evolutionary Applications
Article Title: Investigating food production‐associated DNA methylation changes in paleogenomes: Lack of consistent signals beyond technical noise
doi: 10.1111/eva.13743
Figure Lengend Snippet: The demographic characteristics of the 34 ancient genomes used in this study and their genome‐wide methylation scores. (a) The excavation locations of ancient individuals are included in this study. Color coding indicates subsistence type. (b) Left panel: Violin plots of the methylation score (MS) data related to ancient individuals included in this study. The brown and blue points indicate the mean and the median, respectively. The x ‐axis shows the log2‐transformed MS values. The y ‐axis represents the ancient individuals. Right panel: Zoomed‐in version of the left panel. (c) The distribution of mean MS per individual on CpG islands and genomic sites representing shelves, shores, and open seas.
Article Snippet: To this end, we utilized methylation differences documented between modern‐day HGs and agriculturalists in Central Africa, measured in whole blood samples using bisulfite treatment and the Illumina 450K array (Fagny et al., ).
Techniques: Genome Wide, Methylation, Transformation Assay