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Mednet Inc methylation data
Cross-validation analysis of three epigenetic clocks for centenarians. Age estimation 20-fold cross-validation (LOFO20) of the ENCen40 + , ENCen100 + , and NNCen40 + clocks in blood, saliva, and buccals cells, for different age ranges (columns). The panels relate chronological age ( x -axis) to DNAm age estimates ( y -axis) from the ENCen40 + ( A , B , C ) and NNCen40 + ( D , E , F ), and ENCen100 + ( G , H , I ), respectively. Each column corresponds to a different age range. DNA <t>methylation</t> data from age 40 to 115 ( A , D , G ), 100 to 115 ( B , E , H ), and 80 to 115 ( C , F , I ). Each panel reports the sample size (N), the median absolute error (MAE), Pearson correlation coefficient ( r ), the p value ( p ), and each point is color coded by sex (blue = male)
Methylation Data, supplied by Mednet Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/methylation+data/methylation+data/pmc10400760-337-9-4
Average 90 stars, based on 1 article reviews
methylation data - by Bioz Stars, 2026-11
90/100 stars

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Article Title: Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity

Journal: GeroScience

doi: 10.1007/s11357-023-00731-7

Cross-validation analysis of three epigenetic clocks for centenarians. Age estimation 20-fold cross-validation (LOFO20) of the ENCen40 + , ENCen100 + , and NNCen40 + clocks in blood, saliva, and buccals cells, for different age ranges (columns). The panels relate chronological age ( x -axis) to DNAm age estimates ( y -axis) from the ENCen40 + ( A , B , C ) and NNCen40 + ( D , E , F ), and ENCen100 + ( G , H , I ), respectively. Each column corresponds to a different age range. DNA methylation data from age 40 to 115 ( A , D , G ), 100 to 115 ( B , E , H ), and 80 to 115 ( C , F , I ). Each panel reports the sample size (N), the median absolute error (MAE), Pearson correlation coefficient ( r ), the p value ( p ), and each point is color coded by sex (blue = male)
Figure Legend Snippet: Cross-validation analysis of three epigenetic clocks for centenarians. Age estimation 20-fold cross-validation (LOFO20) of the ENCen40 + , ENCen100 + , and NNCen40 + clocks in blood, saliva, and buccals cells, for different age ranges (columns). The panels relate chronological age ( x -axis) to DNAm age estimates ( y -axis) from the ENCen40 + ( A , B , C ) and NNCen40 + ( D , E , F ), and ENCen100 + ( G , H , I ), respectively. Each column corresponds to a different age range. DNA methylation data from age 40 to 115 ( A , D , G ), 100 to 115 ( B , E , H ), and 80 to 115 ( C , F , I ). Each panel reports the sample size (N), the median absolute error (MAE), Pearson correlation coefficient ( r ), the p value ( p ), and each point is color coded by sex (blue = male)

Techniques Used: Biomarker Discovery, DNA Methylation Assay

Individual CpGs and mean CpG in chromatin states. Chronological age ( x -axis) versus A ELOVL2 methylation ( y -axis) or mean methylation in B chromatin state BivProm2, C target sites of polycomb repressive complex 2, D chromatin state EnhA1, E chromatin state TxEx4, and F chromatin state PromF2. Each panel reports the sample size ( N ), Pearson correlation coefficient ( r ), and the p value ( p ), and red line is the LOWESS regression smooth curve
Figure Legend Snippet: Individual CpGs and mean CpG in chromatin states. Chronological age ( x -axis) versus A ELOVL2 methylation ( y -axis) or mean methylation in B chromatin state BivProm2, C target sites of polycomb repressive complex 2, D chromatin state EnhA1, E chromatin state TxEx4, and F chromatin state PromF2. Each panel reports the sample size ( N ), Pearson correlation coefficient ( r ), and the p value ( p ), and red line is the LOWESS regression smooth curve

Techniques Used: Methylation

Related Articles

Methylation:

Article Title: Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity.
Article Snippet: .. Please contact Steve Horvath (shorvath@mednet.ucla. edu) regarding access to the methylation data. ..

Article Title: Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity
Article Snippet: .. Please contact Steve Horvath (shorvath@mednet.ucla.edu) regarding access to the methylation data. ..



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Image Search Results


RCS analysis for the association between DNAm-predicted GDF15 and risk of frailty. DNAm = DNA methylation, GDF15 = growth differentiation factor 15, RCS = restricted cubic spline.

Journal: Medicine

Article Title: Association of DNA methylation-predicted GDF15 and frailty in older adults based on NHANES 1999–2002

doi: 10.1097/MD.0000000000046816

Figure Lengend Snippet: RCS analysis for the association between DNAm-predicted GDF15 and risk of frailty. DNAm = DNA methylation, GDF15 = growth differentiation factor 15, RCS = restricted cubic spline.

Article Snippet: Methylation data acquisition utilized Illumina’s iScan system for BeadChip imaging.

Techniques: DNA Methylation Assay

The forest plot showed the correlation between DNAm-predicted GDF15 and frailty (OR 95%). DNAm = DNA methylation, GDF15 = growth differentiation factor 15, OR = odds ratio.

Journal: Medicine

Article Title: Association of DNA methylation-predicted GDF15 and frailty in older adults based on NHANES 1999–2002

doi: 10.1097/MD.0000000000046816

Figure Lengend Snippet: The forest plot showed the correlation between DNAm-predicted GDF15 and frailty (OR 95%). DNAm = DNA methylation, GDF15 = growth differentiation factor 15, OR = odds ratio.

Article Snippet: Methylation data acquisition utilized Illumina’s iScan system for BeadChip imaging.

Techniques: DNA Methylation Assay