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Biocartis idylla kras mutation test
Idylla Kras Mutation Test, supplied by Biocartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kras+mutation+testing/idylla+kras/pm40940818-55-3-7
Average 86 stars, based on 1 article reviews
idylla kras mutation test - by Bioz Stars, 2026-10
86/100 stars

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Mutagenesis:

Article Title: KRAS Mutations in Colorectal Adenocarcinoma: Incidence and Association with Histological Features with Particular Reference to Gly12Asp in a Multicenter GIPAD Real-World Study
Article Snippet: Centers 10 and 11: Myriapod NGS Cancer Panel DNA (Diatech Pharmacogenetics), sequencing on Illumina platform (San Diego, CA, USA); Idylla KRAS Mutation Assay (Biocartis, Mechelen, Belgium). .. Center 12: Idylla KRAS Mutation Test (Biocartis). ..

Article Title: 2181 A solution for same-day extended RAS testing
Article Snippet: s S393

Article Title: 2017 Evaluation of the redox state of platelets as prognostic criteria of the combined treatment in patients with rectal cancer efficacy
Article Snippet: s S335 Results: The only differentiating features between Sporadic (45.5% of the CRC), LLS (20.4%) and LS CRCs (34.1%) are the age of onset (68.5 vs 46 vs 47 years of age; p < 0.001) and the existence of cancers in the family (42.4% vs 42.4% vs 81.5%; p < 0.001).. Detection of BRAF V600E is a sensitive (63%) and specific (100%) test in identifying sporadic tumors.. The status of hypermethylation is also essential for sporadic diagnosis but can be traced in LS (3.5%).

Article Title: 2183 Local and systemic antigen-specific systemic immunity in metastatic colorectal cancer patients
Article Snippet: Methods: The Idylla KRAS and NRAS/BRAF/EGFR492 Mutation prototype assays (Biocartis) detect 40 mutations in codons 12 and 13 of exon 2, codons 59 and 61 of exon 3, and codons 117 and 146 of exon 4 of both RAS genes.. Mutations are detected by selective amplification in 10 multiplex PCRs in two Idylla cartridges.. LODs were calculated with plasmid dilutions in 1000 copies of KRAS wt FFPE background.

Article Title: Fluorescent In Situ Hybridization Testing Allows the Diagnosis of NRG1 Gene Fusions in Lung and Pancreas Cancers with No Other Identified Oncogenic Driver.
Article Snippet: .. Based on 5 μm FFPE tumor sections, every PDADK of the cases series was first tested for KRAS mutations using the IdyllaTM KRAS mutation test (Biocartis, Mechelen, Belgium) to differentiate KRAS-mutated samples from KRAS wild-type samples. .. For KRAS wild-type samples, molecular analyses were pursued using RNAseq (Archer® FusionPlex® Lung panel, ArcherDX, Boulder, CO, USA, including NRG1 in the panel of genes analyzed) and NRG1 FISH (ZytoLightSPEC NRG1 Dual Color Break Apart, ZytoVision GmbH, Bremerhaven, Germany).

Article Title: USCAP 2022 Abstracts: Genitourinary Pathology (including renal tumors) (522-659).
Article Snippet: .. A search for KRAS gene mutation was performed using the Idylla KRAS mutation test (Biocartis, Mechelen, Belgium), a CE-IVD labelled, fully automated, real-time PCR-based molecular diagnostics system that allows characterization of predefined hot-spot mutations in exons 2, 3, and 4 of KRAS. .. Immunohistochemical (IHC) staining typically revealed that most of these cells were positive for cytokeratin AE1/AE3, EMA, CD10, carbonic anhydrase IX, and vimentin; and negative for CD68, β human chorionic gonadotropin, TFE3, cathepsin K, Cytokeratin 7, Cytokeratin 20, HMB45 and C-KIT.

Article Title: KRAS Mutations in Colorectal Adenocarcinoma: Incidence and Association with Histological Features with Particular Reference to Gly12Asp in a Multicenter GIPAD Real-World Study.
Article Snippet: • Centers 10 and 11: Myriapod NGS Cancer Panel DNA (Diatech Pharmacogenetics), sequencing on Illumina platform (San Diego, CA, USA); Idylla KRAS Mutation Assay (Biocartis, Mechelen, Belgium). .. • Center 12: Idylla KRAS Mutation Test (Biocartis). ..

Formalin-fixed Paraffin-Embedded:

Article Title: Fluorescent In Situ Hybridization Testing Allows the Diagnosis of NRG1 Gene Fusions in Lung and Pancreas Cancers with No Other Identified Oncogenic Driver.
Article Snippet: .. Based on 5 μm FFPE tumor sections, every PDADK of the cases series was first tested for KRAS mutations using the IdyllaTM KRAS mutation test (Biocartis, Mechelen, Belgium) to differentiate KRAS-mutated samples from KRAS wild-type samples. .. For KRAS wild-type samples, molecular analyses were pursued using RNAseq (Archer® FusionPlex® Lung panel, ArcherDX, Boulder, CO, USA, including NRG1 in the panel of genes analyzed) and NRG1 FISH (ZytoLightSPEC NRG1 Dual Color Break Apart, ZytoVision GmbH, Bremerhaven, Germany).

Polymerase Chain Reaction:

Article Title: USCAP 2022 Abstracts: Genitourinary Pathology (including renal tumors) (522-659).
Article Snippet: .. A search for KRAS gene mutation was performed using the Idylla KRAS mutation test (Biocartis, Mechelen, Belgium), a CE-IVD labelled, fully automated, real-time PCR-based molecular diagnostics system that allows characterization of predefined hot-spot mutations in exons 2, 3, and 4 of KRAS. .. Immunohistochemical (IHC) staining typically revealed that most of these cells were positive for cytokeratin AE1/AE3, EMA, CD10, carbonic anhydrase IX, and vimentin; and negative for CD68, β human chorionic gonadotropin, TFE3, cathepsin K, Cytokeratin 7, Cytokeratin 20, HMB45 and C-KIT.



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