kleanprep  (Norgine BV)

Journal: Frontiers in Pharmacology

Article Title: Comparative effectiveness of treatments for recurrent Clostridioides difficile infection: a network meta-analysis of randomized controlled trials

doi: 10.3389/fphar.2024.1430724

Figure Lengend Snippet: Main characteristics of studies included in the network meta-analysis.

Article Snippet: Van Nood-2013 , Open-label, randomized, controlled trial , Diarrhea (≥3 loose or watery stools per day for at least 2 consecutive days or ≥8 loose stools in 48 h) and a positive stool test for C. difficile toxin , 42 , Vancomycin (500 mg qid, 4 days), followed by bowel lavage with 4 L Macrogol solution (Klean-Prep) on final day of antibiotic treatment and subsequent infusion of FMT solution through a nasoduodenal tube the next day (n = 16) , Vancomycin (500 mg qid, 14 days) (n = 13), or vancomycin with bowel lavage on day 4 or 5 (n = 13) , Absence of diarrhea or persistent diarrhea explained by other causes, with three consecutive negative stool tests for C. difficile toxin , 10 weeks.

Techniques: Infection, Suspension, Enzyme Immunoassay, Polymerase Chain Reaction, Biomarker Discovery, Capsules, Neutralization, Enzyme-linked Immunosorbent Assay

Journal: Endoscopy International Open

Article Title: Efficacy and safety of a new low-volume PEG with citrate and simethicone bowel preparation for pediatric elective colonoscopy: Phase 3 RCT

doi: 10.1055/a-2251-3372

Figure Lengend Snippet: Table 1 Number of subjects in the SAF, FAS and PPS.

Article Snippet: Patients and methods This was a multicenter, randomized, observer-blind, parallel-group, phase 3 clinical trial, where patients were randomized between PMF104 (Clensia) and a conventional PEG-ES (Klean-Prep), and stratified by age stratum (2 to <6; 6 to < 12;12 to <18 years).

Techniques:

Journal: Endoscopy International Open

Article Title: Efficacy and safety of a new low-volume PEG with citrate and simethicone bowel preparation for pediatric elective colonoscopy: Phase 3 RCT

doi: 10.1055/a-2251-3372

Figure Lengend Snippet: Table 3 Analysis of variance (ANOVA) on BBPS score for the three age strata in the PPS and FAS.

Article Snippet: Patients and methods This was a multicenter, randomized, observer-blind, parallel-group, phase 3 clinical trial, where patients were randomized between PMF104 (Clensia) and a conventional PEG-ES (Klean-Prep), and stratified by age stratum (2 to <6; 6 to < 12;12 to <18 years).

Techniques: