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human interleukin 12 rhil 12  (Neumedicines Inc)

 
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    Neumedicines Inc human interleukin 12 rhil 12
    Human Interleukin 12 Rhil 12, supplied by Neumedicines Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/interleukin+12/12+12+human+interleukin+rhil/us12655159-798-5-11
    Average 86 stars, based on 1 article reviews
    human interleukin 12 rhil 12 - by Bioz Stars, 2026-09
    86/100 stars

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    Recombinant:

    Article Title: Deuterated IRAK degraders and uses thereof
    Article Snippet: In some embodiments, an IL-15 based immunotherapeutic is heterodimeric IL-15 (hetIL-15, Novartis/Admune), a fusion complex composed of a synthetic form of endogenous IL-15 complexed to the soluble IL-15 binding protein IL-15 receptor alpha chain (IL15:sIL-15RA), which has been tested in Phase 1 clinical trials for melanoma, renal cell carcinoma, non-small cell lung cancer and head and neck squamous cell carcinoma (NCT02452268). .. In some embodiments, a recombinant human interleukin 12 (rhIL-12) is NM-IL-12 (Neumedicines, Inc.), NCT02544724, or NCT02542124. ..

    Article Title: GPR84 antagonists and uses thereof
    Article Snippet: In some embodiments, an IL-15 based immunotherapeutic is heterodimeric IL-15 (hetIL-15, Novartis/Admune), a fusion complex composed of a synthetic form of endogenous IL-15 complexed to the soluble IL-15 binding protein IL-15 receptor alpha chain (IL15:sIL-15RA), which has been tested in Phase 1 clinical trials for melanoma, renal cell carcinoma, non-small cell lung cancer and head and neck squamous cell carcinoma (NCT02452268). .. In some embodiments, a recombinant human interleukin 12 (rhIL-12) is NM-ILL-12 (Neumedicines, Inc.), NCT02544724, or NCT02542124. ..



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    Cytokine immune response in serum, the in vitro system, and tissue samples. The Th-1 (IFN-γ and IL-12) and Th-2 (IL-4 and IL-10) cytokines were quantified in the serum of immunized animals using ELISA at 2 weeks post-booster: IFN-γ (A) , IL-10 (B) , IL-12 (C) , IL-4 (D) , and IFN-γ/IL-10 ratio (E) . Twelve weeks post-infection IFN-γ (F) , IL-10 (G) , IL-12 (H) , IL-4 (I) , and IFN-γ/IL-10 ratio (J) . All experiments were performed in triplicate, having three biological replicates in each experiment and data are presented here as the mean and standard error. Different vaccinated groups were compared to determine the statistical significance of the data using ANOVA with the Tukey test analysis with p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***) level of significance.

    Journal: Frontiers in Immunology

    Article Title: Mycobacterium tuberculosis antigen-containing exosomes reinforce BCG vaccine efficacy by augmenting long-term protection and memory response against experimental tuberculosis in BALB-C mice

    doi: 10.3389/fimmu.2026.1742207

    Figure Lengend Snippet: Cytokine immune response in serum, the in vitro system, and tissue samples. The Th-1 (IFN-γ and IL-12) and Th-2 (IL-4 and IL-10) cytokines were quantified in the serum of immunized animals using ELISA at 2 weeks post-booster: IFN-γ (A) , IL-10 (B) , IL-12 (C) , IL-4 (D) , and IFN-γ/IL-10 ratio (E) . Twelve weeks post-infection IFN-γ (F) , IL-10 (G) , IL-12 (H) , IL-4 (I) , and IFN-γ/IL-10 ratio (J) . All experiments were performed in triplicate, having three biological replicates in each experiment and data are presented here as the mean and standard error. Different vaccinated groups were compared to determine the statistical significance of the data using ANOVA with the Tukey test analysis with p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***) level of significance.

    Article Snippet: Serum samples collected pre-immunization, post-boost, and 12 weeks post-challenge were analyzed for IgG1 (KLM1629), IgG2a (KLM1488), IFN-γ (KB2011), IL-12 (KLM0020), IL-4 (KLM0051), and IL-10 (KB2072) using GENLISA sandwich ELISA kits (Krishgen BioSystems, USA, catalog numbers as specified).

    Techniques: In Vitro, Enzyme-linked Immunosorbent Assay, Infection