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ImmunoGen Inc immunogen sequence
Immunogen Sequence, supplied by ImmunoGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/immunogenic+sequence/immunogen+sequence/pmc11478043-182-4-4
Average 90 stars, based on 1 article reviews
immunogen sequence - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Blocking Assay:

Article Title: The Combination of an mRNA Immunogen, a TLR7 Agonist and a PD1 Blocking Agent Enhances In-Vitro HIV T-Cell Immune Responses.
Article Snippet: .. The Combination of an mRNA Immunogen, a TLR7 Agonist and a PD1 Blocking Agent Enhances In-Vitro HIV T-Cell Immune Responses. ..

In Vitro:

Article Title: The Combination of an mRNA Immunogen, a TLR7 Agonist and a PD1 Blocking Agent Enhances In-Vitro HIV T-Cell Immune Responses.
Article Snippet: .. The Combination of an mRNA Immunogen, a TLR7 Agonist and a PD1 Blocking Agent Enhances In-Vitro HIV T-Cell Immune Responses. ..

other:

Article Title: Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine.
Article Snippet: Our results demonstrate that both pre-F and G-specific antibodies contribute to neutralizing activity and confirm that G is the primary target for neutralization. mRNA-Immunogen Design Elements Like Signal Peptide and Protein Solubility Does Not Affect Immunogenicity Historically, immunogen design elements like signal peptide and protein solubility have played a role in immunogenicity.

Article Title: Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial.
Article Snippet: The 16 identified HIV-1 regions were assembled in a 529aa immunogen sequence (HTI) and expressed both in a plasmid DNA (DNA.HTI, D)12 and two viral-vectored vaccines based on a modified Vaccinia virus Ankara (MVA.HTI, M)13 and a chimpanzee adenovirus (ChAdOx1.HTI, C)14.

Article Title: Intracellular accumulation of tau oligomers in astrocytes and their synaptotoxic action rely on Amyloid Precursor Protein Intracellular Domain-dependent expression of Glypican-4.
Article Snippet: Several studies including ours reported the detrimental effects of extracellular tau oligomers (ex-oTau) on glutamatergic synaptic transmission and plasticity.. Astrocytes greatly internalize ex-oTau whose intracellular accumulation alters neuro/gliotransmitter handling thereby negatively affecting synaptic function.. Both amyloid precursor protein (APP) and heparan sulfate proteoglycans (HSPGs) are required for oTau internalization in astrocytes but the molecular mechanisms underlying this phenomenon have not been clearly identified yet.

Sequencing:

Article Title: Regional and cellular organization of the autism-associated protein UBE3A/E6AP and its antisense transcript in the brain of the developing rhesus monkey
Article Snippet: .. Notably, this immunogen sequence exhibits high (98%) identity (99 out of 101 amino acids) with the macaque UBE3A protein. .. To label SOX9, we used a polyclonal goat IgG (R and D Systems Cat# AF3075, RRID:AB_2194160) developed using a recombinant human SOX9 (Met1-Lys151).

Article Title: The Expression of Cannabinoid and Cannabinoid-Related Receptors on the Gustatory Cells of the Piglet Tongue
Article Snippet: .. The alignment of the immunogen sequence with the target protein in the pig was 80.3% ( https://blast.ncbi.nlm.nih.gov/Blast.cgi , accessed on 7 January 2018). ..

Article Title: CKAP4 in hepatocellular carcinoma: competitive RETREG1/FAM134B binding, reticulophagy regulation, and cancer progression.
Article Snippet: RETREG1/FAM134B is known for its role as a reticulophagy receptor.. Our previous study established that RETREG1 is upregulated in hepatocellular carcinoma (HCC) and contributes to disease progression by activating the AKT signaling pathway.. However, the specific mechanisms underlying the elevated expression of RETREG1 in HCC remain unclear.

Immunopeptidomics:

Article Title: Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine.
Article Snippet: .. The pre-F/G chimera A B DC FIGURE 2 | Immunogenicity of mRNA Immunogen-Specific Design Elements. (A, C) Serum samples 6 weeks post-boost were assessed for NiV pre-F specific IgG (A) or monomeric G-specific IgG (C) by ELISA. ..

Enzyme-linked Immunosorbent Assay:

Article Title: Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine.
Article Snippet: .. The pre-F/G chimera A B DC FIGURE 2 | Immunogenicity of mRNA Immunogen-Specific Design Elements. (A, C) Serum samples 6 weeks post-boost were assessed for NiV pre-F specific IgG (A) or monomeric G-specific IgG (C) by ELISA. ..



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(A) An alignment of human PAX6 sequences reveals that all fifteen isoforms share the <t>immunogenic</t> sequence (highlighted in dark grey). NCBI sequence numbers are to the left of the sequences which are arranged alphabetically by isoform. (B) The four isoforms of axolotl PAX6 (sequences 1–4) contain the immunogenic sequence as does PAX6 from the Japanese fire-bellied newt (sequence 5) and the hypothetical protein from the Iberian ribbed newt (sequence 6). Sequence 7 is human PAX6. (C) Partial sequence obtained from E . nana containing 16/19 amino acids from the PAX6 immunogenic sequence.
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Image Search Results


(A) An alignment of human PAX6 sequences reveals that all fifteen isoforms share the immunogenic sequence (highlighted in dark grey). NCBI sequence numbers are to the left of the sequences which are arranged alphabetically by isoform. (B) The four isoforms of axolotl PAX6 (sequences 1–4) contain the immunogenic sequence as does PAX6 from the Japanese fire-bellied newt (sequence 5) and the hypothetical protein from the Iberian ribbed newt (sequence 6). Sequence 7 is human PAX6. (C) Partial sequence obtained from E . nana containing 16/19 amino acids from the PAX6 immunogenic sequence.

Journal: PLOS ONE

Article Title: PAX6 protein in neuromasts of the lateral line system of salamanders ( Eurycea )

doi: 10.1371/journal.pone.0293163

Figure Lengend Snippet: (A) An alignment of human PAX6 sequences reveals that all fifteen isoforms share the immunogenic sequence (highlighted in dark grey). NCBI sequence numbers are to the left of the sequences which are arranged alphabetically by isoform. (B) The four isoforms of axolotl PAX6 (sequences 1–4) contain the immunogenic sequence as does PAX6 from the Japanese fire-bellied newt (sequence 5) and the hypothetical protein from the Iberian ribbed newt (sequence 6). Sequence 7 is human PAX6. (C) Partial sequence obtained from E . nana containing 16/19 amino acids from the PAX6 immunogenic sequence.

Article Snippet: Primary antibody was diluted 1:10,000 in 5% non-fat dry milk in Tris-buffered saline with Tween20 (TBST), and half was incubated with custom peptide (Thermo Fisher) matching the antibody’s immunogenic sequence, resuspended in PBS at a concentration at least 5 times the molarity of the antibody.

Techniques: Sequencing