goldengate methylation arrays© (Illumina Inc)
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goldengate methylation arrays©
Goldengate Methylation Arrays©, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
Goldengate Methylation Arrays©, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/goldengate+methylation+array/goldengate+methylation+beadarray/pmc02855718-231-9-8
Average 90 stars, based on 1 article reviews
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2026-11
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Biomarker Discovery:Article Title: Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer. Article Snippet: .. Biomarker Name BiologicalFunction Tumor Site Sample Type Sample Size DNA Processing Technical Approach (Methods) Methylation Status Application Sensitivity (%) Specificity (%) AUC (95% CI) Reference p16 Cell cycleregulation HNC (SCC) Oral rinse (NaCl) 30 tumors and 30 saliva controls Volume: - Kit: Phenol-chloroform extraction/Bisulfite treatment (Sigma, Burlington, MA, USA) MSP Hypermethylation Diagnosis NA NA NA Rosas 2001 [34]MGMT DNA repair NA NA NA DAPK Cell deathregulation NA NA NA TIMP3 Cell cycleregulation HNC (SCC) Oral rinse (25 mL NaCl 0.9%) 60 patients Volume: - Kit: QIAmp tissue kit (Qiagen, Hilden, Germany)/CpGenome DNA modification kit (MP Biomedicals, Irvine, CA, USA) MSP Hypermethylation Diagnosis/ disease monitoring 28 NA NA Righini 2007 [35] ECAD Cell adhesion 20 NA NA p16 Cell cycleregulation 27 NA NA MGMT DNA repair 22 NA NA DAPK Cell deathregulation 15 NA NA RASSF1A Cell cycleregulation 17 NA NA soluble CD44 Cell adhesion HNC(SCC) Oral rinse (5 mL NaCl, 5 s) 102 patients and 69 controls Volume: - Kit: QIAmp DNA mini kit (Qiagen, Hilden, Germany)/bisulfite solution MSP Hypermethylation Diagnosis 62–70 75–88 NA Franzmann 2007 [36] p16 Cell cycleregulation OC (SCC) Unstimulated saliva (7.5 mL) 14 patients and 5 controls Volume: 1 mL Kit: QIAamp Blood (Qiagen, Hilden, Germany)/EpiTect Bisulfite (Qiagen, Hilden, Germany) Methylight Hypermethylation Diagnosis 35 NA NA Viet 2007 [37] MGMT DNA repair 29 NA NA p15 Cell growth regulation, cell death regulation 29 NA NA APC Cell growthregulation 14 NA NA ECAD Cell adhesion 7 NA NA GABRB3 + IL11 + INSR + NOTCH3 + NTRK3 + PXN Cell signaling, cell differentiation, cell adhesion OC (SCC) Unstimulated saliva (7.5 mL) 13 patients and 10 controls Volume: 1 mL Kit:iPrep Chargeswitch Buccal Cell kit (Invitrogen, Waltham, MA, USA)/EZ DNA Methylation kit (Zymo Research, Irvine, CA, USA) Methylation:Article Title: Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer. Article Snippet: .. Biomarker Name BiologicalFunction Tumor Site Sample Type Sample Size DNA Processing Technical Approach (Methods) Methylation Status Application Sensitivity (%) Specificity (%) AUC (95% CI) Reference p16 Cell cycleregulation HNC (SCC) Oral rinse (NaCl) 30 tumors and 30 saliva controls Volume: - Kit: Phenol-chloroform extraction/Bisulfite treatment (Sigma, Burlington, MA, USA) MSP Hypermethylation Diagnosis NA NA NA Rosas 2001 [34]MGMT DNA repair NA NA NA DAPK Cell deathregulation NA NA NA TIMP3 Cell cycleregulation HNC (SCC) Oral rinse (25 mL NaCl 0.9%) 60 patients Volume: - Kit: QIAmp tissue kit (Qiagen, Hilden, Germany)/CpGenome DNA modification kit (MP Biomedicals, Irvine, CA, USA) MSP Hypermethylation Diagnosis/ disease monitoring 28 NA NA Righini 2007 [35] ECAD Cell adhesion 20 NA NA p16 Cell cycleregulation 27 NA NA MGMT DNA repair 22 NA NA DAPK Cell deathregulation 15 NA NA RASSF1A Cell cycleregulation 17 NA NA soluble CD44 Cell adhesion HNC(SCC) Oral rinse (5 mL NaCl, 5 s) 102 patients and 69 controls Volume: - Kit: QIAmp DNA mini kit (Qiagen, Hilden, Germany)/bisulfite solution MSP Hypermethylation Diagnosis 62–70 75–88 NA Franzmann 2007 [36] p16 Cell cycleregulation OC (SCC) Unstimulated saliva (7.5 mL) 14 patients and 5 controls Volume: 1 mL Kit: QIAamp Blood (Qiagen, Hilden, Germany)/EpiTect Bisulfite (Qiagen, Hilden, Germany) Methylight Hypermethylation Diagnosis 35 NA NA Viet 2007 [37] MGMT DNA repair 29 NA NA p15 Cell growth regulation, cell death regulation 29 NA NA APC Cell growthregulation 14 NA NA ECAD Cell adhesion 7 NA NA GABRB3 + IL11 + INSR + NOTCH3 + NTRK3 + PXN Cell signaling, cell differentiation, cell adhesion OC (SCC) Unstimulated saliva (7.5 mL) 13 patients and 10 controls Volume: 1 mL Kit:iPrep Chargeswitch Buccal Cell kit (Invitrogen, Waltham, MA, USA)/EZ DNA Methylation kit (Zymo Research, Irvine, CA, USA) Article Title: The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review Article Snippet: De Jager PL. et al, 2014[ ] , CCS/ comparison of participants in a prospective cohort study, with post-mortem diagnosis of AD. , USA, n = 708, M and W , 60.8% (N = 430) of subjects met a pathological diagnosis of AD. , Cortical brain tissue , Methylation at 425,848 discrete CpG dinucleotides in 708 subjects (Illumina HumanMethylation beadset).Other: Identification of genes near the associated CpGs. , , 137 CpGs were found to be associated with the burden of neuritic amyloid plaques (NP) (p<1.20x 10^-7). When corrected for the proportion of neurons and possible measurement artifacts, 71 CpG associations remained.22 of the NP-associated CpG s were also associated with AD at a genome-wide level of significance, and all displayed at least (p<0.001) some evidence of association with AD. Associated methylated regions included ABCA7 and BIN1 genes, which are known AD susceptibility regions.. .. Fernandez AF. et al, 2012[ ] , CS/ whole genome methylation “fingerprint” including normal tissues, oncogenic tissues, and non-cancerous disease tissues (such as AD and DLB) , Europe, Asia and North America, n = 1628, M and W , N = 11 , Brain tissue and PBMCs , Article Title: DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach Article Snippet: .. In the current study, 60 GC samples underwent prior review by pathologists to ensure this minimum tumor cell content was met prior to methylation analysis using the Article Title: Advances in Prognostic Methylation Biomarkers for Prostate Cancer Article Snippet: .. Article Title: Genome‐wide DNA methylation profiling of CpG islands in a morpholino anthracycline derivative‐resistant leukemia cell line: p38 α as a novel candidate for resistance Article Snippet: .. High‐throughput methylation analysis of multiple CpG sites can be performed with the Article Title: Discovery Of Methylated Circulating DNA Biomarkers For Comprehensive Non-Invasive Monitoring Of Treatment Response In Metastatic Colorectal Cancer Article Snippet: .. While these markers were identified by Roperch et al. using the Extraction:Article Title: Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer. Article Snippet: .. Biomarker Name BiologicalFunction Tumor Site Sample Type Sample Size DNA Processing Technical Approach (Methods) Methylation Status Application Sensitivity (%) Specificity (%) AUC (95% CI) Reference p16 Cell cycleregulation HNC (SCC) Oral rinse (NaCl) 30 tumors and 30 saliva controls Volume: - Kit: Phenol-chloroform extraction/Bisulfite treatment (Sigma, Burlington, MA, USA) MSP Hypermethylation Diagnosis NA NA NA Rosas 2001 [34]MGMT DNA repair NA NA NA DAPK Cell deathregulation NA NA NA TIMP3 Cell cycleregulation HNC (SCC) Oral rinse (25 mL NaCl 0.9%) 60 patients Volume: - Kit: QIAmp tissue kit (Qiagen, Hilden, Germany)/CpGenome DNA modification kit (MP Biomedicals, Irvine, CA, USA) MSP Hypermethylation Diagnosis/ disease monitoring 28 NA NA Righini 2007 [35] ECAD Cell adhesion 20 NA NA p16 Cell cycleregulation 27 NA NA MGMT DNA repair 22 NA NA DAPK Cell deathregulation 15 NA NA RASSF1A Cell cycleregulation 17 NA NA soluble CD44 Cell adhesion HNC(SCC) Oral rinse (5 mL NaCl, 5 s) 102 patients and 69 controls Volume: - Kit: QIAmp DNA mini kit (Qiagen, Hilden, Germany)/bisulfite solution MSP Hypermethylation Diagnosis 62–70 75–88 NA Franzmann 2007 [36] p16 Cell cycleregulation OC (SCC) Unstimulated saliva (7.5 mL) 14 patients and 5 controls Volume: 1 mL Kit: QIAamp Blood (Qiagen, Hilden, Germany)/EpiTect Bisulfite (Qiagen, Hilden, Germany) Methylight Hypermethylation Diagnosis 35 NA NA Viet 2007 [37] MGMT DNA repair 29 NA NA p15 Cell growth regulation, cell death regulation 29 NA NA APC Cell growthregulation 14 NA NA ECAD Cell adhesion 7 NA NA GABRB3 + IL11 + INSR + NOTCH3 + NTRK3 + PXN Cell signaling, cell differentiation, cell adhesion OC (SCC) Unstimulated saliva (7.5 mL) 13 patients and 10 controls Volume: 1 mL Kit:iPrep Chargeswitch Buccal Cell kit (Invitrogen, Waltham, MA, USA)/EZ DNA Methylation kit (Zymo Research, Irvine, CA, USA) Modification:Article Title: Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer. Article Snippet: .. Biomarker Name BiologicalFunction Tumor Site Sample Type Sample Size DNA Processing Technical Approach (Methods) Methylation Status Application Sensitivity (%) Specificity (%) AUC (95% CI) Reference p16 Cell cycleregulation HNC (SCC) Oral rinse (NaCl) 30 tumors and 30 saliva controls Volume: - Kit: Phenol-chloroform extraction/Bisulfite treatment (Sigma, Burlington, MA, USA) MSP Hypermethylation Diagnosis NA NA NA Rosas 2001 [34]MGMT DNA repair NA NA NA DAPK Cell deathregulation NA NA NA TIMP3 Cell cycleregulation HNC (SCC) Oral rinse (25 mL NaCl 0.9%) 60 patients Volume: - Kit: QIAmp tissue kit (Qiagen, Hilden, Germany)/CpGenome DNA modification kit (MP Biomedicals, Irvine, CA, USA) MSP Hypermethylation Diagnosis/ disease monitoring 28 NA NA Righini 2007 [35] ECAD Cell adhesion 20 NA NA p16 Cell cycleregulation 27 NA NA MGMT DNA repair 22 NA NA DAPK Cell deathregulation 15 NA NA RASSF1A Cell cycleregulation 17 NA NA soluble CD44 Cell adhesion HNC(SCC) Oral rinse (5 mL NaCl, 5 s) 102 patients and 69 controls Volume: - Kit: QIAmp DNA mini kit (Qiagen, Hilden, Germany)/bisulfite solution MSP Hypermethylation Diagnosis 62–70 75–88 NA Franzmann 2007 [36] p16 Cell cycleregulation OC (SCC) Unstimulated saliva (7.5 mL) 14 patients and 5 controls Volume: 1 mL Kit: QIAamp Blood (Qiagen, Hilden, Germany)/EpiTect Bisulfite (Qiagen, Hilden, Germany) Methylight Hypermethylation Diagnosis 35 NA NA Viet 2007 [37] MGMT DNA repair 29 NA NA p15 Cell growth regulation, cell death regulation 29 NA NA APC Cell growthregulation 14 NA NA ECAD Cell adhesion 7 NA NA GABRB3 + IL11 + INSR + NOTCH3 + NTRK3 + PXN Cell signaling, cell differentiation, cell adhesion OC (SCC) Unstimulated saliva (7.5 mL) 13 patients and 10 controls Volume: 1 mL Kit:iPrep Chargeswitch Buccal Cell kit (Invitrogen, Waltham, MA, USA)/EZ DNA Methylation kit (Zymo Research, Irvine, CA, USA) Cell Differentiation:Article Title: Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer. Article Snippet: .. Biomarker Name BiologicalFunction Tumor Site Sample Type Sample Size DNA Processing Technical Approach (Methods) Methylation Status Application Sensitivity (%) Specificity (%) AUC (95% CI) Reference p16 Cell cycleregulation HNC (SCC) Oral rinse (NaCl) 30 tumors and 30 saliva controls Volume: - Kit: Phenol-chloroform extraction/Bisulfite treatment (Sigma, Burlington, MA, USA) MSP Hypermethylation Diagnosis NA NA NA Rosas 2001 [34]MGMT DNA repair NA NA NA DAPK Cell deathregulation NA NA NA TIMP3 Cell cycleregulation HNC (SCC) Oral rinse (25 mL NaCl 0.9%) 60 patients Volume: - Kit: QIAmp tissue kit (Qiagen, Hilden, Germany)/CpGenome DNA modification kit (MP Biomedicals, Irvine, CA, USA) MSP Hypermethylation Diagnosis/ disease monitoring 28 NA NA Righini 2007 [35] ECAD Cell adhesion 20 NA NA p16 Cell cycleregulation 27 NA NA MGMT DNA repair 22 NA NA DAPK Cell deathregulation 15 NA NA RASSF1A Cell cycleregulation 17 NA NA soluble CD44 Cell adhesion HNC(SCC) Oral rinse (5 mL NaCl, 5 s) 102 patients and 69 controls Volume: - Kit: QIAmp DNA mini kit (Qiagen, Hilden, Germany)/bisulfite solution MSP Hypermethylation Diagnosis 62–70 75–88 NA Franzmann 2007 [36] p16 Cell cycleregulation OC (SCC) Unstimulated saliva (7.5 mL) 14 patients and 5 controls Volume: 1 mL Kit: QIAamp Blood (Qiagen, Hilden, Germany)/EpiTect Bisulfite (Qiagen, Hilden, Germany) Methylight Hypermethylation Diagnosis 35 NA NA Viet 2007 [37] MGMT DNA repair 29 NA NA p15 Cell growth regulation, cell death regulation 29 NA NA APC Cell growthregulation 14 NA NA ECAD Cell adhesion 7 NA NA GABRB3 + IL11 + INSR + NOTCH3 + NTRK3 + PXN Cell signaling, cell differentiation, cell adhesion OC (SCC) Unstimulated saliva (7.5 mL) 13 patients and 10 controls Volume: 1 mL Kit:iPrep Chargeswitch Buccal Cell kit (Invitrogen, Waltham, MA, USA)/EZ DNA Methylation kit (Zymo Research, Irvine, CA, USA) DNA Methylation Assay:Article Title: Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer. Article Snippet: .. Biomarker Name BiologicalFunction Tumor Site Sample Type Sample Size DNA Processing Technical Approach (Methods) Methylation Status Application Sensitivity (%) Specificity (%) AUC (95% CI) Reference p16 Cell cycleregulation HNC (SCC) Oral rinse (NaCl) 30 tumors and 30 saliva controls Volume: - Kit: Phenol-chloroform extraction/Bisulfite treatment (Sigma, Burlington, MA, USA) MSP Hypermethylation Diagnosis NA NA NA Rosas 2001 [34]MGMT DNA repair NA NA NA DAPK Cell deathregulation NA NA NA TIMP3 Cell cycleregulation HNC (SCC) Oral rinse (25 mL NaCl 0.9%) 60 patients Volume: - Kit: QIAmp tissue kit (Qiagen, Hilden, Germany)/CpGenome DNA modification kit (MP Biomedicals, Irvine, CA, USA) MSP Hypermethylation Diagnosis/ disease monitoring 28 NA NA Righini 2007 [35] ECAD Cell adhesion 20 NA NA p16 Cell cycleregulation 27 NA NA MGMT DNA repair 22 NA NA DAPK Cell deathregulation 15 NA NA RASSF1A Cell cycleregulation 17 NA NA soluble CD44 Cell adhesion HNC(SCC) Oral rinse (5 mL NaCl, 5 s) 102 patients and 69 controls Volume: - Kit: QIAmp DNA mini kit (Qiagen, Hilden, Germany)/bisulfite solution MSP Hypermethylation Diagnosis 62–70 75–88 NA Franzmann 2007 [36] p16 Cell cycleregulation OC (SCC) Unstimulated saliva (7.5 mL) 14 patients and 5 controls Volume: 1 mL Kit: QIAamp Blood (Qiagen, Hilden, Germany)/EpiTect Bisulfite (Qiagen, Hilden, Germany) Methylight Hypermethylation Diagnosis 35 NA NA Viet 2007 [37] MGMT DNA repair 29 NA NA p15 Cell growth regulation, cell death regulation 29 NA NA APC Cell growthregulation 14 NA NA ECAD Cell adhesion 7 NA NA GABRB3 + IL11 + INSR + NOTCH3 + NTRK3 + PXN Cell signaling, cell differentiation, cell adhesion OC (SCC) Unstimulated saliva (7.5 mL) 13 patients and 10 controls Volume: 1 mL Kit:iPrep Chargeswitch Buccal Cell kit (Invitrogen, Waltham, MA, USA)/EZ DNA Methylation kit (Zymo Research, Irvine, CA, USA) Article Title: The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review Article Snippet: De Jager PL. et al, 2014[ ] , CCS/ comparison of participants in a prospective cohort study, with post-mortem diagnosis of AD. , USA, n = 708, M and W , 60.8% (N = 430) of subjects met a pathological diagnosis of AD. , Cortical brain tissue , Methylation at 425,848 discrete CpG dinucleotides in 708 subjects (Illumina HumanMethylation beadset).Other: Identification of genes near the associated CpGs. , , 137 CpGs were found to be associated with the burden of neuritic amyloid plaques (NP) (p<1.20x 10^-7). When corrected for the proportion of neurons and possible measurement artifacts, 71 CpG associations remained.22 of the NP-associated CpG s were also associated with AD at a genome-wide level of significance, and all displayed at least (p<0.001) some evidence of association with AD. Associated methylated regions included ABCA7 and BIN1 genes, which are known AD susceptibility regions.. .. Fernandez AF. et al, 2012[ ] , CS/ whole genome methylation “fingerprint” including normal tissues, oncogenic tissues, and non-cancerous disease tissues (such as AD and DLB) , Europe, Asia and North America, n = 1628, M and W , N = 11 , Brain tissue and PBMCs , Article Title: DNA methylation alterations in Alzheimer’s disease Article Snippet: .. Sanchez-Mut et al . [ ] used a Gas Chromatography:Article Title: DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach Article Snippet: .. In the current study, 60 GC samples underwent prior review by pathologists to ensure this minimum tumor cell content was met prior to methylation analysis using the GoldenGate Methylation BeadArray (Illumina) platform. .. Analysis:Article Title: DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach Article Snippet: .. In the current study, 60 GC samples underwent prior review by pathologists to ensure this minimum tumor cell content was met prior to methylation analysis using the Physiology:Article Title: DNA methylation alterations in Alzheimer’s disease Article Snippet: .. Sanchez-Mut et al . [ ] used a Transgenic Assay:Article Title: DNA methylation alterations in Alzheimer’s disease Article Snippet: .. Sanchez-Mut et al . [ ] used a other:Article Title: Epigenetic Mechanisms Regulate MHC and Antigen Processing Molecules in Human Embryonic and Induced Pluripotent Stem Cells Article Snippet: Methylation was assessed at 1,505 CpG sites using Illumina Goldengate Methylation Arrays© and analyzed as we previously described [ 48 ] . |