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Perlegen Sciences genotyping data
Genotyping Data, supplied by Perlegen Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/genotype+data/genotyping+data/pmc01310643-121-15-19
Average 90 stars, based on 1 article reviews
genotyping data - by Bioz Stars, 2026-11
90/100 stars

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Article Title: The neuronal transporter gene SLC6A15 confers risk to major depression
Article Snippet: Their function is largely unknown and their expression levels are low in the vertebrate brain (Anonymous2009; UniGene, 2009 ).

Article Title: SNPselector: a web tool for selecting SNPs for genetic association studies
Article Snippet: To provide the richest possible dataset, we have merged HapMap genotyping data with other genotyping information, such as Perlegen genotyping data ( Hinds et al. , 2005 ).

Article Title: SNPselector: a web tool for selecting SNPs for genetic association studies
Article Snippet: The Perlegen genotyping data of African American, Caucasian, and Chinese was also added into the SNPselector database.

Article Title: Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa
Article Snippet: The Perlegen genotyping data have been shown to provide useful Tajima's D statistics after empirically accounting for this ascertainment bias , .

Article Title: Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism.
Article Snippet: According to HapMap data, rs1971940 is located in a linkage Molecular Psychiatry (2008) 13, 831–832 & 2008 Nature Publishing Group All rights reserved 1359-4184/08 $30.00 www.nature.com/mp disequilibrium block surrounded by recombination hotspots (HapMap Phase I Release 16c.1 and Perlegen genotyping data), suggesting that rs1971940 might be involved in alternative splicing of PDE4D.

Genotyping:

Article Title: Calculation of Tajima’s D and other neutrality test statistics from low depth next-generation sequencing data
Article Snippet: .. To compare with earlier published results we used the Tajima track [ ] from the UCSC genome browser [ ], which depicts estimated values of Tajima’s D from 24 individuals of European descent from the Perlegen genotyping dataset [ ]. ..



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Image Search Results


The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.

Journal: Genes & Diseases

Article Title: Exploring CISD1 as a multifaceted biomarker in cancer: Implications for diagnosis, prognosis, and immunotherapeutic response

doi: 10.1016/j.gendis.2025.101677

Figure Lengend Snippet: The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.

Article Snippet: Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues.

Techniques: Expressing, Quantitative Proteomics

Quality control of the genotyping dataset. ( a ) Distribution of call rates for the initial 296 samples; ( b ) Distribution of call rates for the final 224 samples; ( c ) Gencall scores at the 10th percentile compared to call rates for the initial 296 samples; ( d ) Gencall scores at the 10th percentile for the remaining 224 samples; ( e ) Gencall scores at the 50th percentile for the initial 296 samples; ( f ) Gencall scores at the 50th percentile for the final 224 samples.

Journal: Scientific Data

Article Title: Genomic landscape of the Great Steppe: Genetic variants in healthy Kazakh individuals

doi: 10.1038/s41597-025-05964-z

Figure Lengend Snippet: Quality control of the genotyping dataset. ( a ) Distribution of call rates for the initial 296 samples; ( b ) Distribution of call rates for the final 224 samples; ( c ) Gencall scores at the 10th percentile compared to call rates for the initial 296 samples; ( d ) Gencall scores at the 10th percentile for the remaining 224 samples; ( e ) Gencall scores at the 50th percentile for the initial 296 samples; ( f ) Gencall scores at the 50th percentile for the final 224 samples.

Article Snippet: Raw genotyping data were downloaded from Macrogen cloud service.

Techniques: Control