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next generation sequencing  (Caris Life Sciences)

 
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    Structured Review

    Caris Life Sciences next generation sequencing
    Next Generation Sequencing, supplied by Caris Life Sciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/generation+sequencing/generation+next+sequencing/pm42296390-33-2-4
    Average 86 stars, based on 1 article reviews
    next generation sequencing - by Bioz Stars, 2026-09
    86/100 stars

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    Related Articles

    Biomarker Discovery:

    Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
    Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

    Next-Generation Sequencing:

    Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
    Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

    Article Title: Corded and hyalinized endometrioid carcinoma: A case report
    Article Snippet: .. Next-Generation Sequencing performed via Caris Life Sciences revealed pathogenic mutations in ARID1A , CTNNB1 (exon 3) , PIK3R1 , PTEN , CTCF , FBXW7 , and FGFR2 with low tumor mutational burden and wildtype POLE status. ..



    Article Title: Actionable Genes and Carcinogenic Pathways for Gastric Cancer in Latinos
    Article Snippet: .. The data were collected and provided by the Precision Oncology Alliance (POA) [ ] using the CARIS Life Sciences next‐generation sequencing (NGS) platform, which employed either a 592‐gene panel or whole‐exome sequencing (WES) to detect mutations, indels, and copy number amplification (CNA). ..

    Sequencing:

    Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
    Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

    Article Title: Actionable Genes and Carcinogenic Pathways for Gastric Cancer in Latinos
    Article Snippet: .. The data were collected and provided by the Precision Oncology Alliance (POA) [ ] using the CARIS Life Sciences next‐generation sequencing (NGS) platform, which employed either a 592‐gene panel or whole‐exome sequencing (WES) to detect mutations, indels, and copy number amplification (CNA). ..

    Mutagenesis:

    Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
    Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

    other:

    Article Title: Comparison of breast and gastric HER2 immunohistochemistry (IHC) scoring criteria in the assessment of endometrial carcinoma.
    Article Snippet: Seven hundred and fifty two endometrial tumors with available HER2 IHC and molecular data by next-generation sequencing (NGS) and whole transcriptome sequencing (WTS) performed by the CLIA-certified molecular profiling laboratory Caris Life Sciences (Phoenix, AZ) were included.

    RNA Sequencing:

    Article Title: Novel Case of a Molecularly Confirmed Low-Grade Fibromyxoid Sarcoma of the Floor of the Mouth and Literature Review
    Article Snippet: .. Tissue samples were sent to Caris Life Sciences (Irving, Texas, USA) for RNA sequencing with a targeted solid tumor fusion panel, using Archer's AMPTM technology to interrogate specific regions of genes and featured a highly optimized oligonucleotide probe pool with specificity for the recurrent break points in the fusion partner genes that are recurrently rearranged in a variety of solid tumors. ..

    Amplification:

    Article Title: Actionable Genes and Carcinogenic Pathways for Gastric Cancer in Latinos
    Article Snippet: .. The data were collected and provided by the Precision Oncology Alliance (POA) [ ] using the CARIS Life Sciences next‐generation sequencing (NGS) platform, which employed either a 592‐gene panel or whole‐exome sequencing (WES) to detect mutations, indels, and copy number amplification (CNA). ..



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    Pacific Biosciences generation long read sequencing platforms
    <t>Single-cell</t> <t>long-read</t> <t>sequencing</t> (scLRS) enhances tumor cell resolution by integrating methods for detecting splicing alterations and genetic variants. Schematic representation of how scLRS can visualize and combine multiple information types within the same cells to improve tumor cell resolution. Created in BioRender. Byrne, A. (2026) https://BioRender.com/mrmobm6 .
    Generation Long Read Sequencing Platforms, supplied by Pacific Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    Single-cell long-read sequencing (scLRS) enhances tumor cell resolution by integrating methods for detecting splicing alterations and genetic variants. Schematic representation of how scLRS can visualize and combine multiple information types within the same cells to improve tumor cell resolution. Created in BioRender. Byrne, A. (2026) https://BioRender.com/mrmobm6 .

    Journal: Frontiers in Oncology

    Article Title: Beyond counting: how single-cell long-read sequencing turns transcriptome complexity into precision targets

    doi: 10.3389/fonc.2026.1800370

    Figure Lengend Snippet: Single-cell long-read sequencing (scLRS) enhances tumor cell resolution by integrating methods for detecting splicing alterations and genetic variants. Schematic representation of how scLRS can visualize and combine multiple information types within the same cells to improve tumor cell resolution. Created in BioRender. Byrne, A. (2026) https://BioRender.com/mrmobm6 .

    Article Snippet: Adopting third-generation long-read sequencing platforms, such as those developed by Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT), offers a solution to overcome this limitation and deepen our understanding of the transcriptome.

    Techniques: Single Cell, Sequencing