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rosetta resolver gene expression data analysis system  (Rosetta Inpharmatics)

 
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    Structured Review

    Rosetta Inpharmatics rosetta resolver gene expression data analysis system
    Rosetta Resolver Gene Expression Data Analysis System, supplied by Rosetta Inpharmatics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gene+expression+data/rosetta+resolver+gene+expression+data+analysis+system/pmc05234822-151-9-18
    Average 90 stars, based on 1 article reviews
    rosetta resolver gene expression data analysis system - by Bioz Stars, 2026-11
    90/100 stars

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    Related Articles

    Microarray:

    Article Title: Compositions and methods for the treatment of tumor of hematopoietic origin
    Article Snippet: After washing, the microarrays are scanned with the Agilent microarray scanner which is capable of exciting and detecting the fluorescence from the cyanine-3 and cyanine-5 fluorescent molecules (532 and 633 nm laser lines). .. The data for each gene on the 60-mer oligonucleotide array was extracted from the scanned microarray image using Agilent feature extraction software which accounts for feature recognition, background subtraction and normalization and the resulting data was loaded into the software package known as the Rosetta Resolver Gene Expression Data Analysis System (Rosetta Inpharmatics, Inc.). ..

    Extraction:

    Article Title: Compositions and methods for the treatment of tumor of hematopoietic origin
    Article Snippet: After washing, the microarrays are scanned with the Agilent microarray scanner which is capable of exciting and detecting the fluorescence from the cyanine-3 and cyanine-5 fluorescent molecules (532 and 633 nm laser lines). .. The data for each gene on the 60-mer oligonucleotide array was extracted from the scanned microarray image using Agilent feature extraction software which accounts for feature recognition, background subtraction and normalization and the resulting data was loaded into the software package known as the Rosetta Resolver Gene Expression Data Analysis System (Rosetta Inpharmatics, Inc.). ..

    Software:

    Article Title: Compositions and methods for the treatment of tumor of hematopoietic origin
    Article Snippet: After washing, the microarrays are scanned with the Agilent microarray scanner which is capable of exciting and detecting the fluorescence from the cyanine-3 and cyanine-5 fluorescent molecules (532 and 633 nm laser lines). .. The data for each gene on the 60-mer oligonucleotide array was extracted from the scanned microarray image using Agilent feature extraction software which accounts for feature recognition, background subtraction and normalization and the resulting data was loaded into the software package known as the Rosetta Resolver Gene Expression Data Analysis System (Rosetta Inpharmatics, Inc.). ..

    Article Title: Dose-response modeling of early molecular and cellular key events in the CAR-mediated hepatocarcinogenesis pathway.
    Article Snippet: Arrays were scanned with an Affymetrix scanner 3000. .. The raw signal intensities from each scan (.cel files) were imported into the gene expression analysis software Rosetta Resolver version 7.2 (Rosetta Inpharmatics, Kirkland, WA). ..

    Gene Expression:

    Article Title: Compositions and methods for the treatment of tumor of hematopoietic origin
    Article Snippet: After washing, the microarrays are scanned with the Agilent microarray scanner which is capable of exciting and detecting the fluorescence from the cyanine-3 and cyanine-5 fluorescent molecules (532 and 633 nm laser lines). .. The data for each gene on the 60-mer oligonucleotide array was extracted from the scanned microarray image using Agilent feature extraction software which accounts for feature recognition, background subtraction and normalization and the resulting data was loaded into the software package known as the Rosetta Resolver Gene Expression Data Analysis System (Rosetta Inpharmatics, Inc.). ..

    Article Title: Sequential Targeting of CD52 and TNF Allows Early Minimization Therapy in Kidney Transplantation: From a Biomarker to Targeting in a Proof-Of-Concept Trial
    Article Snippet: The Agilent Feature Extraction Software (FES version 10.5.1.1) was used to read out and process the microarray image files. .. FES-derived output data files were further processed using the Rosetta Resolver gene expression data analysis system (version 7.1.0.2., Rosetta Inpharmatics LLC). ..

    Article Title: Dose-response modeling of early molecular and cellular key events in the CAR-mediated hepatocarcinogenesis pathway.
    Article Snippet: Arrays were scanned with an Affymetrix scanner 3000. .. The raw signal intensities from each scan (.cel files) were imported into the gene expression analysis software Rosetta Resolver version 7.2 (Rosetta Inpharmatics, Kirkland, WA). ..

    other:

    Article Title: Immunological biomarkers as indicators for outcome after discontinuation of nucleos(t)ide analogue therapy in patients with HBeAg-negative chronic hepatitis B.
    Article Snippet: For determination of differential gene expression FES derived output data files were further analysed using the Rosetta Resolver® Gene expression data analysis system (Rosetta Inpharmatics LLC).

    Article Title: The immunological consequences of pasteurisation: Comparison of the response of human intestinally-derived cells to raw versus pasteurised milk
    Article Snippet: Microarray technology was used to identify differentially expressed biological signatures in human intestinal cell line (HT-29) exposed to raw versus pasteurised milk; 1041 differentially expressed genes ( 1.3 fold change) were identified (P < 0.001) between exposure groups.. These were further identified to be contained within 179 gene ontologies.. Genes more highly expressed (599 or 57.5%) in cells exposed to raw milk were predominately contained within immune-based gene ontologies.

    Article Title: Transcriptomic evaluation of canine suspension-shipped and pre-plated hepatocytes: comparison to liver.
    Article Snippet: Introduction: In vitro assays using rat and human hepatocytes are used for hepatotoxicity studies; however, in vitro methods are less established for canine hepatocytes.. In particular, little is known about the effects of plating and culture on canine hepatocytes.. The goal of this study was to conduct a descriptive analysis of an in vitro canine hepatocyte system to evaluate its utility and limitations.

    Article Title: The response of Bacillus licheniformis to heat and ethanol stress and the role of the SigB regulon.
    Article Snippet: *Correspondence: Birgit Voigt, Institute for Microbiology, Ernst-Moritz-Arndt University, Friedrich-Ludwig-Jahn-Straße 15, D-17487 Greifswald, Germany email: birgit.voigt@uni-greifswald.de Phone: +49 3834 86 4237, Fax: +49 3834 86 4202 Thomas Schweder, Institute for Pharmacy, Ernst-Moritz-Arndt University, Friedrich-Ludwig-JahnStraße 17, D-17487 Greifswald, Germany email: schweder@uni-greifswald.de Phone: +49 3834 86 4212, Fax: +49 3834 86 4238



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    Human Protein Atlas tissue specific gene expression data
    (A) Cohen’s h values for pairwise comparisons between 𝒞 and the other two groups: ℬ and ℐ . Primate <t>Specific</t> Ratios are calculated as in . A higher absolute Cohen’s h indicates a greater difference in ratios between the two compared groups. Green bar represents ℬ , orange bar represents ℐ , and blue bars represent 𝒞 . (B) Results of Fisher’s exact tests for pairwise comparisons between each of ℬ , ℐ , and 𝒞 and each control group ( ℱ and ℛ ), together with the comparison between ℱ and ℛ . Primate Specific Ratios are calculated as in . Statistical significance is denoted by asterisks. Results with p-values less than 0.01 are indicated by two asterisks (**), results with p-values less than 0.05 are indicated by one asterisk (*), and all other results are marked as ns . Green bar represents ℬ , orange bar represents ℐ , blue bar represents 𝒞 , gray bars represent ℛ , and purple bars represent ℱ . (C) The number of tissues corresponding to each quantile for the brain <t>genes</t> and immune-related genes. Green bars represent ℬ , orange bars represent ℐ , and gray bars represent all genes that have at least one highly expressed <t>tissue</t> in Human Protein Atlas [ , ]. (D) The number and ratio of genes highly expressed specifically in brain tissues or immune-related tissues, out of 1019 brain genes and 586 immune-related genes, respectively.
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    Image Search Results


    Journal: Cell Genomics

    Article Title: MultiSP deciphers tissue structure and multicellular communication from spatial multi-omics data

    doi: 10.1016/j.xgen.2026.101141

    Figure Lengend Snippet:

    Article Snippet: 10× Visium human tonsil gene and protein expression data , 10× Genomics , https://www.10xgenomics.com/resources/datasets/gene-protein-expression-library-of-human-tonsil-cytassist-ffpe-2-standard.

    Techniques: Expressing, Software

    (A) Cohen’s h values for pairwise comparisons between 𝒞 and the other two groups: ℬ and ℐ . Primate Specific Ratios are calculated as in . A higher absolute Cohen’s h indicates a greater difference in ratios between the two compared groups. Green bar represents ℬ , orange bar represents ℐ , and blue bars represent 𝒞 . (B) Results of Fisher’s exact tests for pairwise comparisons between each of ℬ , ℐ , and 𝒞 and each control group ( ℱ and ℛ ), together with the comparison between ℱ and ℛ . Primate Specific Ratios are calculated as in . Statistical significance is denoted by asterisks. Results with p-values less than 0.01 are indicated by two asterisks (**), results with p-values less than 0.05 are indicated by one asterisk (*), and all other results are marked as ns . Green bar represents ℬ , orange bar represents ℐ , blue bar represents 𝒞 , gray bars represent ℛ , and purple bars represent ℱ . (C) The number of tissues corresponding to each quantile for the brain genes and immune-related genes. Green bars represent ℬ , orange bars represent ℐ , and gray bars represent all genes that have at least one highly expressed tissue in Human Protein Atlas [ , ]. (D) The number and ratio of genes highly expressed specifically in brain tissues or immune-related tissues, out of 1019 brain genes and 586 immune-related genes, respectively.

    Journal: PLOS One

    Article Title: Comparative genomics of human brain and immune gene preservation across species

    doi: 10.1371/journal.pone.0348713

    Figure Lengend Snippet: (A) Cohen’s h values for pairwise comparisons between 𝒞 and the other two groups: ℬ and ℐ . Primate Specific Ratios are calculated as in . A higher absolute Cohen’s h indicates a greater difference in ratios between the two compared groups. Green bar represents ℬ , orange bar represents ℐ , and blue bars represent 𝒞 . (B) Results of Fisher’s exact tests for pairwise comparisons between each of ℬ , ℐ , and 𝒞 and each control group ( ℱ and ℛ ), together with the comparison between ℱ and ℛ . Primate Specific Ratios are calculated as in . Statistical significance is denoted by asterisks. Results with p-values less than 0.01 are indicated by two asterisks (**), results with p-values less than 0.05 are indicated by one asterisk (*), and all other results are marked as ns . Green bar represents ℬ , orange bar represents ℐ , blue bar represents 𝒞 , gray bars represent ℛ , and purple bars represent ℱ . (C) The number of tissues corresponding to each quantile for the brain genes and immune-related genes. Green bars represent ℬ , orange bars represent ℐ , and gray bars represent all genes that have at least one highly expressed tissue in Human Protein Atlas [ , ]. (D) The number and ratio of genes highly expressed specifically in brain tissues or immune-related tissues, out of 1019 brain genes and 586 immune-related genes, respectively.

    Article Snippet: There are six types of data used in this work: (1) CDS (coding sequence) data of 32 primate species and 4 non-primate species [ , ]; (2) tissue specific gene expression data obtained from the Human Protein Atlas 23.0 [ , ]; (3) 1360 human genes highly expressed in the brain or the immune system [ , ]; (4) 295 random human genes selected using the random.sample() function in Python 3.10.8; (5) 369 human genes each from a distinct HGNC [ ] gene family group; and (6) protein sequences of the genes obtained from UniProt [ ].

    Techniques: Control, Comparison